Chlorine in PDB 6usv: Crystal Structure of GLUN1/GLUN2A Ligand-Binding Domain in Complex with Glycine and Sdz 220-040

The structure of Crystal Structure of GLUN1/GLUN2A Ligand-Binding Domain in Complex with Glycine and Sdz 220-040, PDB code: 6usv was solved by A.Romero-Hernandez, N.Tajima, T.Chou, H.Furukawa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.50 / 2.30
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	59.281, 85.131, 121.675, 90.00, 90.00, 90.00
R / Rfree (%)	19.5 / 25.9

The binding sites of Chlorine atom in the Crystal Structure of GLUN1/GLUN2A Ligand-Binding Domain in Complex with Glycine and Sdz 220-040 (pdb code 6usv). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of GLUN1/GLUN2A Ligand-Binding Domain in Complex with Glycine and Sdz 220-040, PDB code: 6usv:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of GLUN1/GLUN2A Ligand-Binding Domain in Complex with Glycine and Sdz 220-040


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of GLUN1/GLUN2A Ligand-Binding Domain in Complex with Glycine and Sdz 220-040 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl301 b:69.8 occ:1.00 CL0 B:QGP301 0.0 69.8 1.0 C10 B:QGP301 1.7 52.0 1.0 C15 B:QGP301 2.7 51.4 1.0 C12 B:QGP301 2.7 47.0 1.0 OH B:TYR245 3.2 45.1 1.0 C7 B:QGP301 3.2 41.4 1.0 C8 B:QGP301 3.3 38.5 1.0 CD B:GLU16 3.5 46.4 1.0 OE1 B:GLU16 3.6 53.6 1.0 CG B:GLU16 3.7 37.7 1.0 O B:HOH403 3.8 42.3 1.0 CG2 B:VAL218 3.9 45.2 1.0 CE2 B:PHE19 3.9 35.6 1.0 OG B:SER114 4.0 34.8 1.0 C11 B:QGP301 4.0 61.5 1.0 CB B:SER114 4.0 34.5 1.0 C13 B:QGP301 4.0 42.2 1.0 OE2 B:GLU16 4.1 53.1 1.0 CD2 B:PHE19 4.2 39.4 1.0 CZ B:TYR245 4.3 42.2 1.0 C6 B:QGP301 4.4 38.5 1.0 C14 B:QGP301 4.5 61.5 1.0 C9 B:QGP301 4.5 39.9 1.0 CE2 B:TYR245 4.9 37.8 1.0 CZ B:PHE19 4.9 30.2 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of GLUN1/GLUN2A Ligand-Binding Domain in Complex with Glycine and Sdz 220-040


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of GLUN1/GLUN2A Ligand-Binding Domain in Complex with Glycine and Sdz 220-040 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl301 b:87.0 occ:1.00 CL6 B:QGP301 0.0 87.0 1.0 C11 B:QGP301 1.8 61.5 1.0 C15 B:QGP301 2.7 51.4 1.0 C14 B:QGP301 2.7 61.5 1.0 O B:ALA17 4.0 41.8 1.0 C10 B:QGP301 4.0 52.0 1.0 C13 B:QGP301 4.0 42.2 1.0 CE B:LYS222 4.3 53.1 1.0 CG1 B:VAL218 4.5 41.5 1.0 C12 B:QGP301 4.6 47.0 1.0 NZ B:LYS222 4.6 59.8 1.0 CG2 B:VAL218 4.9 45.2 1.0

T.H.Chou, N.Tajima, A.Romero-Hernandez, H.Furukawa. Structural Basis of Functional Transitions in Mammalian Nmda Receptors. Cell V. 182 357 2020.
ISSN: ISSN 1097-4172
PubMed: 32610085
DOI: 10.1016/J.CELL.2020.05.052