Chlorine in PDB 6uzi: Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1

All present enzymatic activity of Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1:
1.8.1.4;

The structure of Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1, PDB code: 6uzi was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.25 / 2.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	74.060, 106.800, 255.700, 90.00, 90.00, 90.00
R / Rfree (%)	16.9 / 23

The structure of Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1 also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Chlorine atom in the Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1 (pdb code 6uzi). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1, PDB code: 6uzi:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl503 b:74.5 occ:1.00 CG A:HIS466 3.6 48.0 1.0 CD2 A:HIS466 3.7 46.7 1.0 ZN A:ZN502 3.8 95.3 1.0 ND1 A:HIS466 3.9 46.2 1.0 CD2 A:LEU384 3.9 30.7 1.0 CB A:HIS466 4.0 46.8 1.0 NE2 A:HIS466 4.1 49.3 1.0 CE1 A:HIS466 4.2 48.1 1.0 OE1 A:GLU450 4.3 69.7 1.0 O A:HOH651 4.4 59.5 1.0 CD A:GLU450 4.5 63.4 1.0 CA A:LEU384 4.6 42.2 1.0 OE2 A:GLU450 4.6 91.3 1.0 CB A:GLU450 4.6 34.1 1.0 O A:ALA383 4.6 47.9 1.0 CE1 A:HIS445 4.7 70.9 1.0 N A:GLY385 4.7 46.6 1.0 ND1 A:HIS445 4.8 68.5 1.0 OE2 A:GLU454 4.9 50.8 1.0 CG A:GLU454 4.9 33.7 1.0 CZ A:PHE379 5.0 42.6 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl502 b:82.2 occ:1.00 ND1 B:HIS466 3.6 40.5 1.0 CG B:HIS466 3.6 43.7 1.0 ZN A:ZN508 3.8 65.5 1.0 CE1 B:HIS466 3.9 42.0 1.0 CD2 B:LEU384 3.9 39.6 1.0 CD2 B:HIS466 3.9 39.6 1.0 NE2 B:HIS466 4.0 40.9 1.0 CB B:HIS466 4.1 40.7 1.0 CD B:GLU450 4.1 50.9 1.0 OE2 B:GLU450 4.1 50.8 1.0 OE1 B:GLU450 4.1 69.2 1.0 CB B:GLU450 4.2 34.9 1.0 O B:HOH644 4.4 39.4 1.0 OE2 B:GLU454 4.6 53.4 1.0 CG B:GLU454 4.7 42.1 1.0 CG B:GLU450 4.8 43.8 1.0 ND1 B:HIS445 4.8 64.7 1.0 CE1 B:HIS445 4.9 53.0 1.0 CD B:GLU454 4.9 51.1 1.0 CZ B:PHE379 4.9 34.5 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl503 b:76.2 occ:1.00 ZN C:ZN502 3.5 0.4 1.0 CD2 C:LEU384 3.6 44.9 1.0 CG C:HIS466 3.9 60.4 1.0 OE1 C:GLU450 4.0 59.3 1.0 ND1 C:HIS466 4.0 52.4 1.0 CD2 C:HIS466 4.1 57.5 1.0 CD C:GLU450 4.2 57.0 1.0 CE1 C:HIS466 4.3 55.2 1.0 CB C:GLU450 4.3 50.9 1.0 CB C:HIS466 4.3 65.9 1.0 NE2 C:HIS466 4.3 59.0 1.0 OE2 C:GLU450 4.4 64.1 1.0 CA C:LEU384 4.7 43.9 1.0 ND1 C:HIS445 4.7 73.5 1.0 CE1 C:HIS445 4.8 74.3 1.0 CG C:GLU454 4.9 71.2 1.0 CG C:GLU450 4.9 51.8 1.0 CG C:LEU384 4.9 46.6 1.0 O C:ALA383 4.9 60.5 1.0 CZ C:PHE379 4.9 55.4 1.0

J.Abendroth, D.M.Dranow, D.D.Lorimer, P.S.Horanyi, T.E.Edwards. Crystal Structure of Dihydrolipoyl Dehydrogenase From Elizabethkingia Anophelis NUHP1 To Be Published.