Chlorine in PDB 6v4m: Trichuris Suis Bcl-2

The structure of Trichuris Suis Bcl-2, PDB code: 6v4m was solved by W.D.Fairlie, E.F.Lee, B.J.Smith, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.20 / 1.60
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	55.248, 55.248, 111.249, 90.00, 90.00, 90.00
R / Rfree (%)	16.9 / 19.2

The binding sites of Chlorine atom in the Trichuris Suis Bcl-2 (pdb code 6v4m). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Trichuris Suis Bcl-2, PDB code: 6v4m:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Trichuris Suis Bcl-2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Trichuris Suis Bcl-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:18.4 occ:1.00 O A:HOH456 3.0 17.0 1.0 O A:HOH446 3.0 31.4 1.0 NE A:ARG39 3.2 16.1 1.0 N A:ARG39 3.3 17.5 1.0 N A:ILE38 3.4 18.4 1.0 NH2 A:ARG39 3.5 14.9 1.0 CB A:TYR26 3.5 12.8 1.0 CB A:ARG39 3.8 15.4 1.0 CG A:TYR26 3.8 11.5 1.0 CZ A:ARG39 3.8 16.1 1.0 N A:GLY37 3.9 17.5 1.0 CG A:ARG39 4.0 14.8 1.0 C A:GLY37 4.0 18.3 1.0 CA A:GLY37 4.0 16.0 1.0 CA A:ARG39 4.1 15.2 1.0 CA A:ILE38 4.2 15.9 1.0 CD A:ARG39 4.2 15.7 1.0 C A:ILE38 4.2 24.4 1.0 CD2 A:TYR26 4.3 14.9 1.0 CD1 A:TYR26 4.4 13.6 1.0 CB A:ILE38 4.4 15.7 1.0 O A:ARG39 4.4 18.4 1.0 O A:HOH515 4.5 19.5 1.0 O A:HOH427 4.7 17.3 1.0 C A:ARG39 4.8 18.1 1.0 CA A:TYR26 4.9 12.1 1.0 C A:PHE36 4.9 20.2 1.0 O A:GLY37 5.0 26.2 1.0

Chlorine binding site 2 out of 3 in the Trichuris Suis Bcl-2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Trichuris Suis Bcl-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl302 b:29.1 occ:1.00 N A:GLU9 3.1 18.2 1.0 CB A:ASN8 3.6 20.5 1.0 CA A:ASN8 3.6 20.6 1.0 CG A:GLU9 3.7 21.9 1.0 C A:ASN8 3.8 18.4 1.0 CB A:GLU9 3.9 19.4 1.0 CA A:GLU9 4.1 17.7 1.0 CD A:GLU9 4.4 35.3 1.0 OE1 A:GLU9 4.5 35.9 1.0 CG A:ASN8 4.8 18.1 1.0 N A:ASN8 5.0 22.1 1.0

Chlorine binding site 3 out of 3 in the Trichuris Suis Bcl-2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Trichuris Suis Bcl-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl303 b:31.9 occ:1.00 O A:HOH482 3.1 21.9 1.0 NE1 A:TRP146 3.3 15.4 1.0 O A:HOH432 3.9 26.9 1.0 O A:ILE100 3.9 15.8 1.0 CD1 A:TRP146 4.0 13.0 1.0 CE2 A:TRP146 4.4 14.3 1.0 CZ2 A:TRP146 4.8 17.0 1.0

N.D.Young, T.J.Harris, M.Evangelista, S.Tran, M.A.Wouters, T.P.Soares Da Costa, N.J.Kershaw, R.B.Gasser, B.J.Smith, E.F.Lee, W.D.Fairlie. Diversity in the Intrinsic Apoptosis Pathway of Nematodes. Commun Biol V. 3 478 2020.
ISSN: ESSN 2399-3642
PubMed: 32859965
DOI: 10.1038/S42003-020-01208-5