Chlorine in PDB 6v75: Crystal Structure of Human PKM2 in Complex with L-Aspartate

All present enzymatic activity of Crystal Structure of Human PKM2 in Complex with L-Aspartate:
2.7.1.40;

The structure of Crystal Structure of Human PKM2 in Complex with L-Aspartate, PDB code: 6v75 was solved by S.Nandi, M.Dey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	55.52 / 2.85
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	82.523, 157.955, 93.031, 90.00, 101.08, 90.00
R / Rfree (%)	24.6 / 28.4

The structure of Crystal Structure of Human PKM2 in Complex with L-Aspartate also contains other interesting chemical elements:

Magnesium	(Mg)	4 atoms
Potassium	(K)	6 atoms

The binding sites of Chlorine atom in the Crystal Structure of Human PKM2 in Complex with L-Aspartate (pdb code 6v75). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human PKM2 in Complex with L-Aspartate, PDB code: 6v75:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human PKM2 in Complex with L-Aspartate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human PKM2 in Complex with L-Aspartate within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl606 b:47.8 occ:1.00 ND2 C:ASN75 3.6 43.6 1.0 CG2 C:THR50 3.9 45.8 1.0 NH1 C:ARG73 4.0 46.2 1.0 C C:SER362 4.2 55.5 1.0 CB C:SER362 4.2 47.8 1.0 N C:GLY363 4.3 52.2 1.0 O C:SER362 4.4 50.8 1.0 CB C:ASN75 4.4 46.4 1.0 CG C:ASN75 4.5 44.3 1.0 CA C:SER362 4.5 47.3 1.0 CB C:ALA366 4.7 57.3 1.0 CB C:THR50 4.7 53.2 1.0 OG C:SER362 4.7 59.1 1.0 OG1 C:THR50 4.7 54.9 1.0 CZ C:ARG73 4.7 44.9 1.0 NH2 C:ARG73 4.7 48.1 1.0 CA C:GLY363 4.8 52.0 1.0

S.Nandi, M.Dey. Biochemical and Structural Investigation of Pyurvate Kinase Muscle Isoform 2 Regulation By Amino Acids To Be Published.