Chlorine in PDB 6vcb: Cryo-Em Structure of the Glucagon-Like Peptide-1 Receptor in Complex with G Protein, Glp-1 Peptide and A Positive Allosteric Modulator

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Cryo-Em Structure of the Glucagon-Like Peptide-1 Receptor in Complex with G Protein, Glp-1 Peptide and A Positive Allosteric Modulator (pdb code 6vcb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Cryo-Em Structure of the Glucagon-Like Peptide-1 Receptor in Complex with G Protein, Glp-1 Peptide and A Positive Allosteric Modulator, PDB code: 6vcb:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 6vcb

Go back to Chlorine Binding Sites List in 6vcb
Chlorine binding site 1 out of 2 in the Cryo-Em Structure of the Glucagon-Like Peptide-1 Receptor in Complex with G Protein, Glp-1 Peptide and A Positive Allosteric Modulator


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of the Glucagon-Like Peptide-1 Receptor in Complex with G Protein, Glp-1 Peptide and A Positive Allosteric Modulator within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Cl501

b:82.6
occ:1.00
CL07 R:QW7501 0.0 82.6 1.0
C06 R:QW7501 1.8 82.6 1.0
C08 R:QW7501 2.8 82.6 1.0
C05 R:QW7501 2.8 82.6 1.0
C09 R:QW7501 3.0 82.6 1.0
CA R:LEU142 3.3 78.4 1.0
CB R:TYR145 3.6 71.4 1.0
N R:LEU142 3.6 78.4 1.0
O R:LEU141 3.6 80.5 1.0
C R:LEU141 3.7 80.5 1.0
CB R:LEU142 3.7 78.4 1.0
CG R:TYR145 4.0 71.4 1.0
C10 R:QW7501 4.0 82.6 1.0
C04 R:QW7501 4.0 82.6 1.0
C30 R:QW7501 4.0 82.6 1.0
C32 R:QW7501 4.0 82.6 1.0
N11 R:QW7501 4.1 82.6 1.0
CG R:LEU142 4.2 78.4 1.0
CD2 R:TYR145 4.2 71.4 1.0
CG2 P:VAL16 4.3 81.7 1.0
C31 R:QW7501 4.4 82.6 1.0
C R:LEU142 4.5 78.4 1.0
CZ P:PHE12 4.5 73.0 1.0
C03 R:QW7501 4.6 82.6 1.0
CD1 R:LEU142 4.6 78.4 1.0
CB R:LEU141 4.6 80.5 1.0
O R:LEU142 4.7 78.4 1.0
CD1 R:TYR145 4.8 71.4 1.0
CA R:LEU141 4.8 80.5 1.0

Chlorine binding site 2 out of 2 in 6vcb

Go back to Chlorine Binding Sites List in 6vcb
Chlorine binding site 2 out of 2 in the Cryo-Em Structure of the Glucagon-Like Peptide-1 Receptor in Complex with G Protein, Glp-1 Peptide and A Positive Allosteric Modulator


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Cryo-Em Structure of the Glucagon-Like Peptide-1 Receptor in Complex with G Protein, Glp-1 Peptide and A Positive Allosteric Modulator within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Cl501

b:82.6
occ:1.00
CL33 R:QW7501 0.0 82.6 1.0
C32 R:QW7501 1.8 82.6 1.0
C03 R:QW7501 2.8 82.6 1.0
C08 R:QW7501 2.8 82.6 1.0
N11 R:QW7501 2.9 82.6 1.0
C12 R:QW7501 3.0 82.6 1.0
O02 R:QW7501 3.0 82.6 1.0
C09 R:QW7501 3.1 82.6 1.0
C10 R:QW7501 3.1 82.6 1.0
C31 R:QW7501 3.5 82.6 1.0
CA R:LYS202 3.6 85.3 1.0
N13 R:QW7501 3.7 82.6 1.0
O R:LEU201 3.7 76.8 1.0
N R:LYS202 3.8 85.3 1.0
C R:LEU201 3.8 76.8 1.0
C14 R:QW7501 3.9 82.6 1.0
C04 R:QW7501 4.0 82.6 1.0
C06 R:QW7501 4.0 82.6 1.0
CB R:LYS202 4.1 85.3 1.0
C01 R:QW7501 4.1 82.6 1.0
CB R:SER206 4.2 93.5 1.0
C30 R:QW7501 4.4 82.6 1.0
CB R:LEU201 4.5 76.8 1.0
C05 R:QW7501 4.6 82.6 1.0
CG R:LYS202 4.6 85.3 1.0
CA R:LEU201 4.8 76.8 1.0
C R:LYS202 4.9 85.3 1.0
OG R:SER206 5.0 93.5 1.0
CG P:LEU20 5.0 90.7 1.0

Reference:

A.B.Bueno, B.Sun, F.S.Willard, D.Feng, J.D.Ho, D.B.Wainscott, A.D.Showalter, M.Vieth, Q.Chen, C.Stutsman, B.Chau, J.Ficorilli, F.J.Agejas, G.R.Cumming, A.Jimenez, I.Rojo, T.S.Kobilka, B.K.Kobilka, K.W.Sloop. Structural Insights Into Probe-Dependent Positive Allosterism of the Glp-1 Receptor. Nat.Chem.Biol. V. 16 1105 2020.
ISSN: ESSN 1552-4469
PubMed: 32690941
DOI: 10.1038/S41589-020-0589-7
Page generated: Sat Dec 12 14:16:32 2020

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