Chlorine in PDB 6vrh: Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Paroxetine and 8B6 Fab

The structure of Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Paroxetine and 8B6 Fab also contains other interesting chemical elements:

Fluorine

(F)

1 atom

The binding sites of Chlorine atom in the Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Paroxetine and 8B6 Fab (pdb code 6vrh). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Paroxetine and 8B6 Fab, PDB code: 6vrh:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Paroxetine and 8B6 Fab


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Paroxetine and 8B6 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl703 b:0.6 occ:1.00 OH A:TYR121 2.5 0.4 1.0 OG A:SER372 2.7 97.6 1.0 NE2 A:GLN332 2.7 0.8 1.0 OG A:SER336 3.1 95.9 1.0 CB A:SER336 3.5 95.9 1.0 CZ A:TYR121 3.5 0.4 1.0 CB A:SER372 3.5 97.6 1.0 CD A:GLN332 3.8 0.8 1.0 CE1 A:TYR121 3.8 0.4 1.0 CD1 A:PHE105 3.9 0.4 1.0 OD1 A:ASN101 4.0 95.5 1.0 CG A:GLN332 4.0 0.8 1.0 CG A:PHE105 4.1 0.4 1.0 CB A:PHE105 4.1 0.4 1.0 CG A:ASN101 4.2 95.5 1.0 ND2 A:ASN101 4.3 95.5 1.0 CE2 A:TYR121 4.6 0.4 1.0 O A:GLN332 4.6 0.8 1.0 CE1 A:PHE105 4.6 0.4 1.0 OE1 A:GLN332 4.9 0.8 1.0 CA A:SER372 4.9 97.6 1.0 CA A:SER336 5.0 95.9 1.0 O A:GLY100 5.0 97.8 1.0 CD2 A:PHE105 5.0 0.4 1.0 CB A:ASN101 5.0 95.5 1.0

J.A.Coleman, V.Navratna, D.Antermite, D.Yang, J.Bull, E.Gouaux. Molecular Basis For the Binding of the Antidepressant Paroxetine at the Central Site of the Human Serotonin Transporter To Be Published.