Chlorine in PDB 6w3z: Crystal Structure of Brugia Malayi Deoxyhypusine Synthase (Dhps)

The structure of Crystal Structure of Brugia Malayi Deoxyhypusine Synthase (Dhps), PDB code: 6w3z was solved by A.S.Santiago, C.V.Dos Reis, P.Z.Ramos, H.A.Klippel, S.F.Silva, C.F.Zanelli, K.B.Massirer, P.Arruda, A.M.Edwards, R.M.Counago, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.41 / 2.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	69.753, 136.320, 75.883, 90.00, 92.92, 90.00
R / Rfree (%)	18.8 / 21.6

The binding sites of Chlorine atom in the Crystal Structure of Brugia Malayi Deoxyhypusine Synthase (Dhps) (pdb code 6w3z). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Brugia Malayi Deoxyhypusine Synthase (Dhps), PDB code: 6w3z:

Chlorine binding site 1 out of 1 in the Crystal Structure of Brugia Malayi Deoxyhypusine Synthase (Dhps)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Brugia Malayi Deoxyhypusine Synthase (Dhps) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl403 b:82.2 occ:1.00 NZ C:LYS254 3.7 56.3 1.0 O B:PHE197 3.9 36.7 1.0 OD1 B:ASP196 4.0 63.3 1.0 CG B:GLN192 4.2 39.1 1.0 C B:PHE197 4.4 36.3 1.0 O B:HOH521 4.4 30.5 1.0 CA B:SER198 4.5 31.0 1.0 O B:HOH505 4.6 43.9 1.0 O B:ASP196 4.6 45.3 1.0 CD B:GLN192 4.7 41.8 1.0 C B:ASP196 4.7 43.6 1.0 N B:SER198 4.7 32.0 1.0 CB B:SER198 4.7 30.9 1.0 O B:GLN192 5.0 40.9 1.0 CG B:ASP196 5.0 60.1 1.0

S.F.Silva, A.H.Klippel, P.Z.Ramos, A.D.S.Santiago, S.R.Valentini, M.H.Bengtson, K.B.Massirer, E.Bilsland, R.M.Counago, C.F.Zanelli. Structural Features and Development of An Assay Platform of the Parasite Target Deoxyhypusine Synthase of Brugia Malayi and Leishmania Major. Plos Negl Trop Dis V. 14 08762 2020.
ISSN: ESSN 1935-2735
PubMed: 33044977
DOI: 10.1371/JOURNAL.PNTD.0008762