Chlorine in PDB 6wie: Post-Catalytic Nicked Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate

Enzymatic activity of Post-Catalytic Nicked Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate

All present enzymatic activity of Post-Catalytic Nicked Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate:
2.7.7.7;

Protein crystallography data

The structure of Post-Catalytic Nicked Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate, PDB code: 6wie was solved by A.M.Kaminski, T.A.Kunkel, L.C.Pedersen, K.Bebenek, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.90 / 1.50
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 60.073, 62.247, 118.318, 90.00, 90.00, 90.00
R / Rfree (%) 17 / 18.7

Other elements in 6wie:

The structure of Post-Catalytic Nicked Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms
Sodium (Na) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Post-Catalytic Nicked Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate (pdb code 6wie). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Post-Catalytic Nicked Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate, PDB code: 6wie:

Chlorine binding site 1 out of 1 in 6wie

Go back to Chlorine Binding Sites List in 6wie
Chlorine binding site 1 out of 1 in the Post-Catalytic Nicked Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Post-Catalytic Nicked Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl505

b:47.3
occ:1.00
N A:LEU326 3.1 17.0 1.0
CA A:LYS325 3.8 15.6 1.0
C A:LYS325 3.9 17.4 1.0
CA A:LEU326 4.0 19.2 1.0
CB A:LEU326 4.0 23.4 1.0
CB A:LYS325 4.0 20.9 1.0
N A:GLN327 4.1 22.0 1.0
CG A:LYS325 4.2 24.2 1.0
CG A:LEU326 4.3 29.2 1.0
C A:LEU326 4.4 17.6 1.0
CE A:LYS325 4.6 30.8 1.0
CG A:GLN327 4.7 42.9 1.0
CD1 A:LEU149 4.7 36.4 1.0
CD2 A:LEU149 4.8 45.4 1.0
CD1 A:LEU326 4.9 41.6 1.0
O A:GLN327 5.0 22.9 1.0

Reference:

A.M.Kaminski, J.M.Pryor, D.A.Ramsden, T.A.Kunkel, L.C.Pedersen, K.Bebenek. Structural Snapshots of Human Dna Polymerase Mu Engaged on A Dna Double-Strand Break. Nat Commun V. 11 4784 2020.
ISSN: ESSN 2041-1723
PubMed: 32963245
DOI: 10.1038/S41467-020-18506-5
Page generated: Sat Dec 12 14:30:47 2020

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