Chlorine in PDB 6wvn: Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.

The structure of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine., PDB code: 6wvn was solved by G.Minasov, L.Shuvalova, M.Rosas-Lemus, O.Kiryukhina, J.S.Brunzelle, K.J.F.Satchell, Center For Structural Genomics Of Infectious Diseases(Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.35 / 2.00
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	169.372, 169.372, 52.083, 90.00, 90.00, 120.00
R / Rfree (%)	16.2 / 17.8

The structure of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 15;

Binding sites:

The binding sites of Chlorine atom in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. (pdb code 6wvn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 15 binding sites of Chlorine where determined in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine., PDB code: 6wvn:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Chlorine binding site 1 out of 15 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7101 b:98.6 occ:1.00 NE A:ARG7077 3.0 73.9 1.0 NH2 A:ARG7053 3.2 78.3 1.0 NH2 A:ARG7077 3.2 83.0 1.0 CZ A:ARG7077 3.5 81.2 1.0 O A:HOH7275 3.6 60.9 1.0 CD A:ARG7077 4.0 66.3 1.0 CZ A:ARG7053 4.2 77.0 1.0 CG A:ARG7077 4.3 57.3 1.0 O A:HOH7347 4.4 62.9 1.0 NE A:ARG7053 4.6 72.8 1.0 NH1 A:ARG7077 4.8 84.3 1.0 O A:LYS7075 4.9 44.0 1.0

Chlorine binding site 2 out of 15 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7102 b:0.4 occ:1.00 O A:HOH7396 2.9 50.9 0.5 O A:HOH7396 3.2 60.7 0.5 CG A:GLN7036 3.7 53.6 1.0 O A:PRO7034 3.7 37.2 1.0 NE2 A:GLN7036 4.0 62.1 1.0 CD A:GLN7036 4.2 60.7 1.0 C A:PRO7034 4.3 38.2 1.0 CB A:PRO7034 4.3 41.5 1.0 N A:GLN7036 4.6 40.1 1.0 O A:HOH7432 4.7 45.7 0.5 O A:HOH7286 4.7 43.5 1.0 CB A:GLN7036 4.8 47.6 1.0 CA A:PRO7034 4.9 39.6 1.0 C A:ILE7035 5.0 38.4 1.0 N A:ILE7035 5.0 36.8 1.0

Chlorine binding site 3 out of 15 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7103 b:69.4 occ:1.00 N A:GLU6945 3.2 38.0 0.6 N A:GLU6945 3.2 37.4 0.4 O A:HOH7474 3.9 66.0 1.0 CL A:CL7104 3.9 56.9 0.3 CA A:LYS6944 4.0 36.2 1.0 CA A:GLU6945 4.0 40.2 0.6 CB A:GLU6945 4.0 44.8 0.6 CA A:GLU6945 4.0 38.5 0.4 CB A:GLU6945 4.0 41.3 0.4 C A:LYS6944 4.0 36.3 1.0 CB A:LYS6944 4.3 34.4 1.0 C A:GLU6945 4.3 39.0 0.6 C A:GLU6945 4.3 38.1 0.4 CD A:LYS6944 4.4 37.7 1.0 N A:GLY6946 4.4 39.5 1.0 CG A:GLU6945 4.6 48.5 0.6 CG A:GLU6945 4.6 43.0 0.4 CL A:CL7104 4.8 66.6 0.7 CG A:LYS6944 5.0 35.2 1.0 O A:GLU6945 5.0 37.3 0.6

Chlorine binding site 4 out of 15 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7104 b:66.6 occ:0.65 CL A:CL7104 0.0 66.6 0.7 CL A:CL7104 2.4 56.9 0.3 O A:HOH7382 2.6 43.5 0.3 N A:GLY6946 3.2 39.5 1.0 O A:HOH7382 3.4 45.7 0.7 CA A:GLY6946 3.5 38.5 1.0 CB A:GLU6945 4.1 41.3 0.4 CB A:GLU6945 4.1 44.8 0.6 C A:GLU6945 4.4 39.0 0.6 C A:GLU6945 4.4 38.1 0.4 OE2 A:GLU6945 4.6 60.7 0.6 C A:GLY6946 4.8 36.9 1.0 CL A:CL7103 4.8 69.4 1.0 CA A:GLU6945 4.8 40.2 0.6 CA A:GLU6945 4.8 38.5 0.4 O A:HOH7437 5.0 56.1 1.0

Chlorine binding site 5 out of 15 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7104 b:56.9 occ:0.35 CL A:CL7104 0.0 56.9 0.3 CL A:CL7104 2.4 66.6 0.7 CA A:GLY6946 3.8 38.5 1.0 N A:GLY6946 3.8 39.5 1.0 CL A:CL7103 3.9 69.4 1.0 O A:HOH7382 4.2 43.5 0.3 O A:HOH7437 4.8 56.1 1.0 C A:GLU6945 4.8 39.0 0.6 C A:GLU6945 4.8 38.1 0.4

Chlorine binding site 6 out of 15 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7105 b:70.2 occ:1.00 N A:LEU6812 3.0 36.4 1.0 N A:ASN6811 3.4 35.5 1.0 CB A:PRO6810 3.5 35.5 1.0 CB A:LEU6812 3.5 37.9 1.0 CA A:LEU6812 3.8 36.8 1.0 C A:PRO6810 3.9 35.2 1.0 O A:HOH7357 3.9 40.1 1.0 C A:ASN6811 3.9 35.9 1.0 CA A:ASN6811 4.0 37.2 1.0 CA A:PRO6810 4.1 34.0 1.0 CB A:ASN6811 4.2 39.9 1.0 O A:PRO6810 4.6 34.7 1.0 CG A:PRO6810 4.9 35.2 1.0 CG A:LEU6812 4.9 39.9 1.0 N A:TYR6813 4.9 33.7 1.0 C A:LEU6812 4.9 34.5 1.0

Chlorine binding site 7 out of 15 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7106 b:72.6 occ:1.00 N A:LEU6834 2.9 39.4 1.0 O A:HOH7467 3.5 72.9 1.0 O A:ALA6832 3.5 43.2 1.0 O A:HOH7425 3.5 64.8 1.0 CB A:LEU6834 3.6 38.8 1.0 CA A:LEU6834 3.8 38.7 1.0 C A:THR6833 3.9 41.4 1.0 CA A:THR6833 3.9 43.8 1.0 O A:LEU6834 3.9 37.6 1.0 CG A:LEU6834 4.0 38.2 1.0 O A:HOH7242 4.1 52.9 1.0 C A:LEU6834 4.3 38.7 1.0 C A:ALA6832 4.5 42.9 1.0 CD1 A:LEU6834 4.5 38.7 1.0 O A:HOH7304 4.6 64.0 1.0 N A:THR6833 4.7 42.8 1.0 O4 A:SO47121 4.9 83.4 0.7 CG2 A:THR6833 4.9 47.4 1.0 CB A:THR6833 5.0 46.0 1.0

Chlorine binding site 8 out of 15 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7107 b:78.2 occ:1.00 N A:ILE6910 3.0 43.2 1.0 CB A:ILE6910 3.8 46.6 1.0 CA A:LEU6909 3.8 41.9 1.0 O A:ILE6910 3.8 45.4 1.0 CA A:ILE6910 3.8 43.9 1.0 C A:LEU6909 3.9 41.2 1.0 CG1 A:ILE6910 4.0 46.0 1.0 O A:THR6908 4.1 42.2 1.0 O A:HOH7412 4.1 63.1 1.0 C A:ILE6910 4.3 43.8 1.0 CD2 A:LEU6909 4.5 45.9 1.0 CB A:LEU6909 4.7 41.9 1.0 OG A:SER7090 4.7 61.6 1.0 CB A:SER7090 4.8 50.1 1.0 N A:LEU6909 4.8 39.7 1.0 C A:THR6908 4.8 41.1 1.0

Chlorine binding site 9 out of 15 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7108 b:92.5 occ:1.00 NZ A:LYS6939 3.7 84.1 1.0 CD A:LYS6939 3.9 77.0 1.0 CE A:LYS6939 4.1 80.7 1.0 CG A:LYS6939 4.7 75.1 1.0

Chlorine binding site 10 out of 15 in the Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 10 of Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7- Methyl-Gpppa and S-Adenosylmethionine. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7109 b:96.9 occ:1.00 CB A:ASN7066 3.8 78.6 1.0 N A:ASP7067 3.8 74.1 1.0 CG A:ASP7067 4.0 82.3 1.0 OD2 A:ASP7067 4.0 88.9 1.0 CB A:ASP7067 4.2 79.7 1.0 OD1 A:ASP7067 4.4 79.5 1.0 CA A:ASN7066 4.5 76.7 1.0 CA A:ASP7067 4.6 74.5 1.0 C A:ASN7066 4.7 73.9 1.0 CG A:ASN7066 4.7 77.2 1.0

G.Minasov, L.Shuvalova, M.Rosas-Lemus, O.Kiryukhina, J.S.Brunzelle, K.J.F.Satchell, Center For Structural Genomics Of Infectious Diseases(Csgid). Crystal Structure of NSP16-NSP10 From Sars-Cov-2 in Complex with 7-Methyl-Gpppa and S-Adenosylmethionine. To Be Published.