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Chlorine in PDB 6ww0: Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone AnalogEnzymatic activity of Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog
All present enzymatic activity of Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog:
1.14.14.19; 1.14.14.32; Protein crystallography data
The structure of Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog, PDB code: 6ww0
was solved by
E.M.Petrunak,
A.G.Bart,
E.E.Scott,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ww0:
The structure of Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog
(pdb code 6ww0). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog, PDB code: 6ww0: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6ww0Go back to Chlorine Binding Sites List in 6ww0
Chlorine binding site 1 out
of 2 in the Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 6ww0Go back to Chlorine Binding Sites List in 6ww0
Chlorine binding site 2 out
of 2 in the Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog
Mono view Stereo pair view
Reference:
E.M.Petrunak,
A.G.Bart,
E.E.Scott,
R.J.Auchus.
Human Cytochrome P450 17A1 Structures with Metabolites of Prostate Cancer Drug Abiraterone Reveal Substrate-Binding Plasticity and A Second Steroid Binding Site To Be Published.
Page generated: Sat Jul 10 12:23:54 2021
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