Chlorine »
PDB 6wup-6x4l »
6ww0 »
Chlorine in PDB 6ww0: Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog
Enzymatic activity of Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog
All present enzymatic activity of Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog:
1.14.14.19; 1.14.14.32;
1.14.14.19; 1.14.14.32;
Protein crystallography data
The structure of Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog, PDB code: 6ww0
was solved by
E.M.Petrunak,
A.G.Bart,
E.E.Scott,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 38.68 / 2.01 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 85.722, 151.182, 169.944, 90, 90, 90 |
| R / Rfree (%) | 18.5 / 21.8 |
Other elements in 6ww0:
The structure of Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog also contains other interesting chemical elements:
| Iron | (Fe) | 4 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog
(pdb code 6ww0). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog, PDB code: 6ww0:
Jump to Chlorine binding site number: 1; 2;
In total 2 binding sites of Chlorine where determined in the Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog, PDB code: 6ww0:
Jump to Chlorine binding site number: 1; 2;
Chlorine binding site 1 out of 2 in 6ww0
Go back to
Chlorine Binding Sites List in 6ww0
Chlorine binding site 1 out
of 2 in the Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog within 5.0Å range:
|
Chlorine binding site 2 out of 2 in 6ww0
Go back to
Chlorine Binding Sites List in 6ww0
Chlorine binding site 2 out
of 2 in the Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Human Steroidogenic Cytochrome P450 17A1 with 3-Keto-5ALPHA- Abiraterone Analog within 5.0Å range:
|
Reference:
E.M.Petrunak,
A.G.Bart,
E.E.Scott,
R.J.Auchus.
Human Cytochrome P450 17A1 Structures with Metabolites of Prostate Cancer Drug Abiraterone Reveal Substrate-Binding Plasticity and A Second Steroid Binding Site To Be Published.
Page generated: Mon Jul 29 16:56:39 2024
Last articles
Zn in 9JYWZn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
