Chlorine in PDB 6x3j: Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)

The structure of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46), PDB code: 6x3j was solved by H.A.Chaires, J.S.Fraser, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	86.51 / 2.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	104.800, 109.220, 173.030, 90.00, 90.00, 90.00
R / Rfree (%)	23.4 / 27.1

The structure of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) also contains other interesting chemical elements:

Fluorine	(F)	7 atoms
Magnesium	(Mg)	2 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 11;

Binding sites:

The binding sites of Chlorine atom in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) (pdb code 6x3j). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 11 binding sites of Chlorine where determined in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46), PDB code: 6x3j:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Chlorine binding site 1 out of 11 in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl403 b:65.2 occ:1.00 O B:HOH528 2.5 58.4 1.0 O A:HOH526 2.7 45.6 1.0 O B:HOH542 2.9 86.1 1.0 O A:HOH535 2.9 43.2 1.0 HB3 B:LEU56 3.8 40.9 1.0 HD22 B:LEU56 3.8 41.1 1.0 H B:TYR57 3.9 44.3 1.0 CE1 B:TYR57 4.0 47.9 1.0 CZ B:TYR57 4.1 47.0 1.0 HE1 B:TYR57 4.2 44.6 1.0 CD1 B:TYR57 4.4 47.0 1.0 OH B:TYR57 4.4 48.4 1.0 CE2 B:TYR57 4.4 45.0 1.0 HG3 A:PRO76 4.5 38.0 1.0 N B:TYR57 4.6 42.6 1.0 OD2 A:ASP44 4.6 48.7 1.0 CD2 B:LEU56 4.7 40.6 1.0 HD1 B:TYR57 4.7 44.5 1.0 CG B:TYR57 4.7 45.0 1.0 CB B:LEU56 4.7 40.7 1.0 HH B:TYR57 4.7 45.2 1.0 HD23 B:LEU56 4.7 41.1 1.0 CD2 B:TYR57 4.7 43.8 1.0 HA B:LEU56 4.8 41.0 1.0 O B:HOH511 4.8 52.3 1.0 HE2 B:TYR57 4.8 44.5 1.0 HA B:TYR57 4.9 44.7 1.0

Chlorine binding site 2 out of 11 in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl404 b:57.0 occ:1.00 H B:GLY117 2.5 47.0 1.0 HB3 B:LEU115 2.7 48.2 1.0 HB3 B:ASP64 2.9 44.7 1.0 HA2 B:GLY117 3.1 47.2 1.0 N B:GLY117 3.3 44.4 1.0 ND2 B:ASN83 3.5 51.0 1.0 H B:LYS116 3.5 49.3 1.0 HD13 B:LEU115 3.6 49.1 1.0 CA B:GLY117 3.6 44.0 1.0 CB B:LEU115 3.6 49.3 1.0 HD22 B:ASN83 3.7 49.4 1.0 CG B:ASN83 3.7 51.8 1.0 HD21 B:ASN83 3.7 49.4 1.0 CB B:ASP64 3.8 40.6 1.0 HB2 B:ASN83 3.8 49.1 1.0 HD22 B:LEU115 3.9 47.5 1.0 HG22 B:ILE62 3.9 55.3 1.0 HB2 B:LEU115 3.9 48.2 1.0 HB2 B:ASP64 4.0 44.7 1.0 HB3 B:ASN83 4.0 49.1 1.0 N B:LYS116 4.0 55.0 1.0 OD1 B:ASN83 4.1 52.0 1.0 C B:GLY117 4.1 42.8 1.0 CB B:ASN83 4.1 52.8 1.0 O B:GLY117 4.3 42.3 1.0 HG23 B:ILE62 4.3 55.3 1.0 HA B:LEU115 4.4 47.6 1.0 CD1 B:LEU115 4.4 51.7 1.0 CG2 B:ILE62 4.4 58.6 1.0 HG21 B:ILE62 4.4 55.3 1.0 CG B:LEU115 4.4 50.4 1.0 CA B:LEU115 4.5 48.3 1.0 C B:LYS116 4.5 53.8 1.0 HA B:ASP64 4.5 45.2 1.0 HA3 B:GLY117 4.5 47.2 1.0 C B:LEU115 4.5 47.6 1.0 CD2 B:LEU115 4.6 49.7 1.0 CG B:ASP64 4.6 40.1 1.0 CA B:ASP64 4.7 41.5 1.0 HD11 B:LEU115 4.8 49.1 1.0 N B:ASP118 4.9 51.3 1.0 CA B:LYS116 4.9 54.3 1.0 OD2 B:ASP64 4.9 39.0 1.0 H B:ASP64 5.0 45.7 1.0

Chlorine binding site 3 out of 11 in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl402 b:66.1 occ:1.00 H C:TYR57 3.1 37.2 1.0 HB3 C:LEU56 3.7 37.1 1.0 HD22 C:LEU56 3.8 37.4 1.0 N C:TYR57 4.0 37.4 1.0 CE1 C:TYR57 4.2 39.9 1.0 HA C:LEU56 4.2 37.4 1.0 CD1 C:TYR57 4.2 39.4 1.0 HA C:TYR57 4.3 37.8 1.0 CZ C:TYR57 4.4 38.9 1.0 HE1 C:TYR57 4.4 38.5 1.0 HD1 C:TYR57 4.5 38.0 1.0 CG C:TYR57 4.5 38.0 1.0 HD13 C:LEU56 4.5 37.6 1.0 CB C:LEU56 4.5 38.0 1.0 CE2 C:TYR57 4.6 37.4 1.0 CA C:TYR57 4.6 38.4 1.0 HH C:TYR59 4.7 47.3 1.0 CD2 C:TYR57 4.7 36.9 1.0 CA C:LEU56 4.7 38.0 1.0 CD2 C:LEU56 4.7 37.5 1.0 C C:LEU56 4.9 39.4 1.0 OH C:TYR59 4.9 52.8 1.0 OH C:TYR57 5.0 39.5 1.0

Chlorine binding site 4 out of 11 in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl403 b:85.8 occ:1.00 H C:ASP10 2.2 49.8 1.0 HD22 C:ASN13 2.6 57.5 1.0 HB3 C:ASP10 3.1 52.4 1.0 N C:ASP10 3.1 57.3 1.0 HE3 F:MET101 3.3 73.2 1.0 HG3 F:MET101 3.4 72.6 1.0 HB2 C:PRO9 3.4 46.2 1.0 ND2 C:ASN13 3.4 62.3 1.0 HA C:PRO9 3.4 48.2 1.0 HB3 C:ASN13 3.5 60.1 1.0 HB2 C:ASP10 3.6 52.4 1.0 CB C:ASP10 3.6 58.0 1.0 HB2 C:ASN13 3.7 60.1 1.0 HB3 C:PRO9 3.9 46.2 1.0 CB C:PRO9 3.9 49.1 1.0 CA C:ASP10 3.9 58.8 1.0 CA C:PRO9 3.9 51.3 1.0 HD21 C:ASN13 3.9 57.5 1.0 CB C:ASN13 3.9 64.5 1.0 HA C:PRO16 4.0 46.5 1.0 C C:PRO9 4.0 53.1 1.0 HB3 C:PRO16 4.1 47.2 1.0 CE F:MET101 4.1 81.9 1.0 O C:ASP10 4.1 55.8 1.0 CG C:ASN13 4.1 62.3 1.0 CG F:MET101 4.2 78.1 1.0 SD F:MET101 4.3 80.8 1.0 C C:ASP10 4.5 58.3 1.0 O C:PRO16 4.7 43.5 1.0 HE1 F:MET101 4.7 73.2 1.0 HE2 F:MET101 4.7 73.2 1.0 O C:HOH529 4.7 60.4 1.0 HA C:ASP10 4.7 52.1 1.0 CA C:PRO16 4.7 43.5 1.0 HG2 F:MET101 4.7 72.6 1.0 CB C:PRO16 4.8 44.9 1.0 HE2 C:PHE25 4.8 52.2 1.0 HB2 C:PRO16 5.0 47.2 1.0

Chlorine binding site 5 out of 11 in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl402 b:73.7 occ:1.00 O F:HOH534 2.9 70.0 1.0 CE1 E:TYR57 3.9 46.7 1.0 HE1 E:TYR57 3.9 47.0 1.0 CZ E:TYR57 4.1 45.6 1.0 H E:TYR57 4.1 43.6 1.0 CD1 E:TYR57 4.3 44.8 1.0 OD2 F:ASP44 4.4 49.9 1.0 OH E:TYR57 4.4 48.1 1.0 HG3 F:PRO76 4.5 46.5 1.0 HB3 E:LEU56 4.5 38.0 1.0 HD1 E:TYR57 4.5 46.6 1.0 HD22 E:LEU56 4.6 38.0 1.0 CE2 E:TYR57 4.7 42.6 1.0 HH E:TYR57 4.7 46.8 1.0 HH E:TYR59 4.7 61.7 1.0 CG E:TYR57 4.8 41.8 1.0 OH E:TYR59 4.9 61.8 1.0 F19 E:O7V401 4.9 77.3 1.0 N E:TYR57 4.9 39.7 1.0 HA E:TYR57 4.9 45.0 1.0 CD2 E:TYR57 5.0 40.6 1.0

Chlorine binding site 6 out of 11 in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl403 b:65.0 occ:1.00 H E:SER174 2.5 68.0 1.0 HB3 E:PHE173 2.6 59.9 1.0 HG E:SER174 2.6 69.8 1.0 HG21 E:VAL177 3.1 60.1 1.0 HA E:PHE173 3.1 60.2 1.0 N E:SER174 3.3 73.8 1.0 HD1 E:PHE173 3.3 59.0 1.0 CB E:PHE173 3.4 56.3 1.0 OG E:SER174 3.5 76.9 1.0 HB E:VAL177 3.6 59.1 1.0 CA E:PHE173 3.7 56.5 1.0 HG11 E:VAL177 3.7 57.8 1.0 CG2 E:VAL177 3.8 68.0 1.0 HG23 E:VAL177 4.0 60.1 1.0 C E:PHE173 4.0 56.7 1.0 CD1 E:PHE173 4.0 56.5 1.0 CB E:VAL177 4.1 66.2 1.0 HB2 E:PHE173 4.1 59.9 1.0 HB3 E:SER174 4.2 70.2 1.0 CG E:PHE173 4.2 55.9 1.0 CB E:SER174 4.2 77.1 1.0 CA E:SER174 4.4 74.8 1.0 CG1 E:VAL177 4.4 66.2 1.0 HG22 E:VAL177 4.6 60.1 1.0 HG12 E:VAL177 4.8 57.8 1.0

Chlorine binding site 7 out of 11 in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl404 b:90.0 occ:1.00 H E:ILE17 2.3 55.1 1.0 HD2 E:PRO16 2.7 53.2 1.0 HB E:ILE17 2.7 54.4 1.0 O E:ASN20 2.8 34.5 1.0 O E:LEU23 2.8 44.5 1.0 HA E:LEU15 2.9 47.6 1.0 HB3 E:LEU15 3.0 48.8 1.0 O E:ILE17 3.0 58.5 1.0 HB3 E:ASN20 3.0 38.2 1.0 HB3 E:LEU23 3.1 40.3 1.0 N E:ILE17 3.1 56.2 1.0 C E:LEU15 3.4 43.0 1.0 CA E:LEU15 3.4 43.1 1.0 CD E:PRO16 3.4 48.9 1.0 N E:PRO16 3.5 50.4 1.0 CB E:ILE17 3.5 56.2 1.0 CA E:ILE17 3.6 56.9 1.0 CB E:LEU15 3.6 44.6 1.0 HD23 E:LEU15 3.7 47.5 1.0 C E:ILE17 3.7 58.3 1.0 C E:LEU23 3.8 43.1 1.0 HD23 E:LEU23 3.8 40.2 1.0 CB E:ASN20 3.8 35.1 1.0 C E:ASN20 3.9 35.9 1.0 HD3 E:PRO16 3.9 53.2 1.0 OD1 E:ASN20 3.9 32.3 1.0 O E:LEU15 3.9 44.3 1.0 HD22 E:LEU15 4.0 47.5 1.0 H E:LEU23 4.0 41.5 1.0 CB E:LEU23 4.0 43.1 1.0 CG E:ASN20 4.0 33.3 1.0 HD22 E:LEU23 4.0 40.2 1.0 HD12 E:ILE17 4.1 52.2 1.0 HG13 E:ILE17 4.1 53.2 1.0 C E:PRO16 4.2 51.2 1.0 CD2 E:LEU15 4.2 44.0 1.0 CA E:LEU23 4.3 42.8 1.0 CG1 E:ILE17 4.3 55.5 1.0 HB2 E:LEU15 4.3 48.8 1.0 H E:ASN20 4.3 41.9 1.0 CD2 E:LEU23 4.4 42.8 1.0 CA E:ASN20 4.4 36.9 1.0 CA E:PRO16 4.4 50.8 1.0 N E:LEU23 4.4 44.0 1.0 HG22 E:ILE17 4.5 55.1 1.0 HB2 E:LEU23 4.5 40.3 1.0 HA E:ILE17 4.6 55.4 1.0 CG E:LEU15 4.6 44.9 1.0 HG2 E:PRO16 4.6 52.6 1.0 CG E:PRO16 4.6 48.5 1.0 HB2 E:ASN20 4.6 38.2 1.0 CG2 E:ILE17 4.6 57.4 1.0 HA E:GLN24 4.6 54.8 1.0 CD1 E:ILE17 4.7 54.8 1.0 HA E:ARG21 4.7 56.9 1.0 N E:LEU15 4.8 43.4 1.0 CG E:LEU23 4.8 42.5 1.0 N E:ASN20 4.8 39.0 1.0 N E:GLN24 4.9 51.5 1.0 ND2 E:ASN20 4.9 33.2 1.0 N E:ARG21 5.0 75.2 1.0

Chlorine binding site 8 out of 11 in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl405 b:91.2 occ:1.00 H E:GLY163 2.0 43.1 1.0 HD21 C:ASN164 2.2 52.4 1.0 HA E:ALA149 2.7 47.8 1.0 N E:GLY163 2.8 39.7 1.0 HB2 E:ALA149 2.8 47.8 1.0 O E:ALA147 3.0 47.1 1.0 ND2 C:ASN164 3.0 49.3 1.0 HA2 E:GLY163 3.1 43.9 1.0 N E:ALA149 3.2 50.7 1.0 CA E:ALA149 3.2 50.4 1.0 OD1 C:ASN164 3.3 48.9 1.0 CB E:ALA149 3.4 49.9 1.0 HB2 E:GLU148 3.4 57.2 1.0 CA E:GLY163 3.4 41.0 1.0 H E:ALA149 3.5 47.5 1.0 C E:GLU148 3.5 54.6 1.0 HA3 E:GLY162 3.5 36.9 1.0 HB3 E:ALA146 3.6 41.3 1.0 O E:HOH523 3.6 41.5 1.0 CG C:ASN164 3.6 49.1 1.0 HA2 E:GLY162 3.6 36.9 1.0 HD22 C:ASN164 3.7 52.4 1.0 C E:GLY162 3.7 42.7 1.0 HB1 E:ALA149 3.8 47.8 1.0 O E:GLU148 3.8 55.4 1.0 CA E:GLY162 3.8 41.5 1.0 C E:ALA147 4.0 45.2 1.0 C E:GLY163 4.1 39.4 1.0 O E:GLY163 4.2 37.3 1.0 HG11 C:VAL150 4.2 41.6 1.0 CB E:GLU148 4.2 57.1 1.0 HB3 E:ALA149 4.2 47.8 1.0 HA3 E:GLY163 4.3 43.9 1.0 O E:ALA146 4.3 36.3 1.0 CA E:GLU148 4.3 54.7 1.0 HB1 E:ALA146 4.3 41.3 1.0 CB E:ALA146 4.4 39.6 1.0 N E:GLU148 4.5 54.1 1.0 HG21 C:VAL150 4.5 42.0 1.0 HE1 C:MET134 4.6 61.5 1.0 C E:ALA146 4.6 37.2 1.0 HB3 E:GLU148 4.6 57.2 1.0 C E:ALA149 4.7 49.0 1.0 H E:VAL150 4.8 46.4 1.0 O E:GLY162 4.8 43.2 1.0 N E:ALA147 5.0 44.5 1.0

Chlorine binding site 9 out of 11 in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl402 b:74.0 occ:1.00 O F:HOH523 2.4 42.6 1.0 HE1 F:TYR57 3.9 41.6 1.0 CE1 F:TYR57 3.9 46.0 1.0 H F:TYR57 4.1 43.8 1.0 CZ F:TYR57 4.2 44.5 1.0 CD1 F:TYR57 4.3 46.1 1.0 OD2 C:ASP44 4.3 47.5 1.0 HD22 F:LEU56 4.4 30.9 1.0 HD1 F:TYR57 4.5 42.5 1.0 HG3 C:PRO76 4.6 41.7 1.0 HH F:TYR59 4.6 42.0 1.0 OH F:TYR57 4.6 45.0 1.0 HB3 F:LEU56 4.6 31.4 1.0 F19 F:O7V401 4.7 57.1 1.0 OH F:TYR59 4.7 49.3 1.0 O F:HOH504 4.7 55.6 1.0 CE2 F:TYR57 4.8 42.7 1.0 HA F:TYR57 4.8 44.1 1.0 CG F:TYR57 4.9 44.4 1.0 N F:TYR57 4.9 44.3 1.0

Chlorine binding site 10 out of 11 in the Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 10 of Crystal Structure of Streptogramin A Acetyltransferase Vata From Staphylococcus Aureus in Complex with Streptogramin Analog F0224 (46) within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl403 b:87.0 occ:1.00 H F:GLY91 2.2 48.7 1.0 H F:ASP90 2.6 55.0 1.0 O F:SER92 2.8 43.3 1.0 O C:ILE202 2.8 42.8 1.0 N F:ASP90 2.9 54.7 1.0 N F:GLY91 2.9 49.4 1.0 HG2 F:ARG88 2.9 53.1 1.0 HB2 F:ASP90 3.2 56.3 1.0 HB3 F:ARG88 3.2 52.5 1.0 HD3 F:ARG88 3.3 53.6 1.0 O F:ARG88 3.3 50.2 1.0 C F:ARG88 3.3 51.7 1.0 HA F:MET89 3.4 54.8 1.0 N F:MET89 3.4 51.7 1.0 C F:MET89 3.4 51.1 1.0 C F:SER92 3.5 41.4 1.0 C F:GLY91 3.5 45.8 1.0 N F:SER92 3.5 41.6 1.0 CA F:MET89 3.6 50.6 1.0 CG F:ARG88 3.6 54.9 1.0 CA F:ASP90 3.6 55.3 1.0 C F:ASP90 3.7 53.7 1.0 CA F:GLY91 3.7 47.5 1.0 CB F:ARG88 3.8 53.8 1.0 H F:SER92 3.8 38.7 1.0 H F:MET89 3.8 55.0 1.0 CD F:ARG88 3.9 55.6 1.0 CB F:ASP90 3.9 56.7 1.0 HA F:THR93 3.9 47.0 1.0 HG23 C:ILE202 3.9 42.0 1.0 C C:ILE202 4.0 43.5 1.0 O F:GLY91 4.1 45.0 1.0 HA3 F:GLY91 4.1 48.5 1.0 CA F:SER92 4.2 40.4 1.0 HA C:ILE202 4.2 43.0 1.0 HE F:ARG88 4.2 54.3 1.0 CA F:ARG88 4.2 53.0 1.0 HH22 C:ARG172 4.2 49.2 1.0 N F:THR93 4.3 42.8 1.0 O F:MET89 4.4 50.5 1.0 NE F:ARG88 4.4 56.8 1.0 HG3 F:ARG88 4.5 53.1 1.0 HB3 F:ASP90 4.5 56.3 1.0 HA2 F:GLY91 4.5 48.5 1.0 HA F:ASP90 4.6 55.6 1.0 HG22 F:THR93 4.6 46.5 1.0 CA F:THR93 4.6 43.7 1.0 CA C:ILE202 4.7 44.2 1.0 HB2 F:ARG88 4.7 52.5 1.0 HH21 C:ARG172 4.7 49.2 1.0 HD2 F:ARG88 4.7 53.6 1.0 HA F:SER92 4.8 38.2 1.0 HA F:ARG88 4.8 51.8 1.0 NH2 C:ARG172 4.8 50.4 1.0 CG F:ASP90 4.8 58.5 1.0 CG2 C:ILE202 4.8 43.6 1.0 HA C:ASN203 4.9 56.1 1.0 O F:ASP90 4.9 53.4 1.0 HB3 F:SER92 5.0 38.4 1.0 HG22 C:ILE202 5.0 42.0 1.0 H F:THR93 5.0 47.2 1.0

Q.Li, J.Pellegrino, D.J.Lee, A.A.Tran, H.A.Chaires, R.Wang, J.E.Park, K.Ji, D.Chow, N.Zhang, A.F.Brilot, J.T.Biel, G.Van Zundert, K.Borrelli, D.Shinabarger, C.Wolfe, B.Murray, M.P.Jacobson, E.Muhle, O.Chesneau, J.S.Fraser, I.B.Seiple. Synthetic Group A Streptogramin Antibiotics That Overcome Vat Resistance. Nature V. 586 145 2020.
ISSN: ESSN 1476-4687
PubMed: 32968273
DOI: 10.1038/S41586-020-2761-3