Atomistry » Chlorine » PDB 6x5s-6xi7 » 6x7q
Atomistry »
  Chlorine »
    PDB 6x5s-6xi7 »
      6x7q »

Chlorine in PDB 6x7q: Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa

Enzymatic activity of Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa

All present enzymatic activity of Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa:
2.3.1.28;

Protein crystallography data

The structure of Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa, PDB code: 6x7q was solved by A.B.Benjamin, L.M.Stunkard, J.Ling, J.N.Nice, J.R.Lohman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.33 / 1.68
Space group P 42 21 2
Cell size a, b, c (Å), α, β, γ (°) 106.918, 106.918, 126.596, 90, 90, 90
R / Rfree (%) 15.7 / 20.1

Other elements in 6x7q:

The structure of Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa (pdb code 6x7q). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa, PDB code: 6x7q:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in 6x7q

Go back to Chlorine Binding Sites List in 6x7q
Chlorine binding site 1 out of 6 in the Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl304

b:58.0
occ:1.00
 CL1 A:CLM304 0.0 58.0 1.0
C1 A:CLM304 1.8 40.4 1.0
C2 A:CLM304 2.7 28.1 1.0
CL2 A:CLM304 2.9 39.7 1.0
O2 A:CLM304 2.9 26.5 1.0
O C:HOH569 3.5 28.4 1.0
ND2 C:ASN140 3.8 24.8 1.0
N2 A:CLM304 3.9 25.0 1.0
OE1 C:GLN86 3.9 23.0 1.0
C8 A:CLM304 4.1 28.0 1.0
OD1 C:ASN140 4.2 22.6 1.0
C7 A:CLM304 4.2 23.5 1.0
CG C:ASN140 4.2 22.1 1.0
CD2 A:LEU24 4.3 23.6 1.0
CZ C:PHE129 4.6 17.2 1.0
C9 A:CLM304 4.6 27.7 1.0
C6 A:CLM304 4.8 22.8 1.0
CE1 C:PHE129 4.8 16.6 1.0
CZ A:PHE19 4.8 17.1 1.0
CE2 A:PHE19 4.9 16.4 1.0
O9B A:CLM304 4.9 39.3 1.0

Chlorine binding site 2 out of 6 in 6x7q

Go back to Chlorine Binding Sites List in 6x7q
Chlorine binding site 2 out of 6 in the Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl304

b:39.7
occ:1.00
 CL2 A:CLM304 0.0 39.7 1.0
C1 A:CLM304 1.8 40.4 1.0
C2 A:CLM304 2.6 28.1 1.0
CL1 A:CLM304 2.9 58.0 1.0
O2 A:CLM304 3.0 26.5 1.0
N2 A:CLM304 3.4 25.0 1.0
CB C:ALA99 3.6 13.3 1.0
CE1 C:PHE129 3.7 16.6 1.0
CZ C:PHE129 3.8 17.2 1.0
OE1 C:GLN86 4.0 23.0 1.0
OH A:TYR20 4.1 20.4 1.0
O C:HOH412 4.4 40.9 1.0
ND2 C:ASN140 4.5 24.8 1.0
CD C:GLN86 4.6 19.4 1.0
CD1 C:LEU128 4.7 16.9 1.0
C3 A:CLM304 4.7 23.5 1.0
CE2 C:PHE97 4.7 14.2 1.0
CD1 C:PHE129 4.8 17.0 1.0
CE2 C:PHE129 4.9 18.2 1.0
CA C:ALA99 5.0 12.8 1.0
O C:HOH416 5.0 21.6 1.0

Chlorine binding site 3 out of 6 in 6x7q

Go back to Chlorine Binding Sites List in 6x7q
Chlorine binding site 3 out of 6 in the Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl301

b:72.5
occ:1.00
 CL1 B:CLM301 0.0 72.5 1.0
C1 B:CLM301 1.8 45.0 1.0
C2 B:CLM301 2.6 31.7 1.0
O2 B:CLM301 2.7 24.8 1.0
CL2 B:CLM301 2.9 53.1 1.0
O A:HOH593 3.6 42.9 1.0
N2 B:CLM301 3.9 25.7 1.0
CD1 B:LEU24 4.1 15.4 0.5
ND2 A:ASN140 4.2 28.1 1.0
C10 B:CLM301 4.2 28.8 1.0
CD2 B:LEU24 4.2 19.3 0.5
OE1 A:GLN86 4.2 28.7 1.0
C11 B:CLM301 4.3 26.7 1.0
C8 A:PG4303 4.3 48.8 1.0
OD1 A:ASN140 4.4 28.8 1.0
CG A:ASN140 4.5 25.5 1.0
CZ B:PHE19 4.5 16.9 1.0
C9 B:CLM301 4.5 28.6 1.0
CZ A:PHE129 4.6 21.2 1.0
CE2 B:PHE19 4.6 16.9 1.0
O5 A:PG4303 4.8 47.2 1.0
C6 B:CLM301 4.8 24.7 1.0
CE1 A:PHE129 4.8 19.9 1.0
O9B B:CLM301 4.9 37.9 1.0
C3 B:CLM301 5.0 26.2 1.0

Chlorine binding site 4 out of 6 in 6x7q

Go back to Chlorine Binding Sites List in 6x7q
Chlorine binding site 4 out of 6 in the Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl301

b:53.1
occ:1.00
 CL2 B:CLM301 0.0 53.1 1.0
C1 B:CLM301 1.7 45.0 1.0
C2 B:CLM301 2.6 31.7 1.0
CL1 B:CLM301 2.9 72.5 1.0
O2 B:CLM301 3.1 24.8 1.0
N2 B:CLM301 3.3 25.7 1.0
CB A:ALA99 3.5 15.6 1.0
CE1 A:PHE129 3.6 19.9 1.0
OE1 A:GLN86 3.7 28.7 1.0
CZ A:PHE129 3.8 21.2 1.0
O A:HOH429 4.2 29.9 1.0
ND2 A:ASN140 4.3 28.1 1.0
OH B:TYR20 4.3 19.6 1.0
CD A:GLN86 4.5 24.8 1.0
C3 B:CLM301 4.6 26.2 1.0
CD1 A:PHE129 4.7 19.8 1.0
O A:HOH549 4.8 21.6 1.0
CG2 A:THR88 4.9 18.5 1.0
CA A:ALA99 4.9 15.1 1.0
CE2 A:PHE97 5.0 14.9 1.0

Chlorine binding site 5 out of 6 in 6x7q

Go back to Chlorine Binding Sites List in 6x7q
Chlorine binding site 5 out of 6 in the Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl301

b:60.8
occ:1.00
 CL1 C:CLM301 0.0 60.8 1.0
C1 C:CLM301 1.8 42.2 1.0
C2 C:CLM301 2.6 34.0 1.0
O2 C:CLM301 2.8 24.2 1.0
CL2 C:CLM301 2.9 45.5 1.0
O B:HOH595 3.5 27.5 1.0
ND2 B:ASN140 3.6 26.0 1.0
N2 C:CLM301 3.7 27.4 1.0
C8 C:CLM301 3.8 26.7 1.0
OE1 B:GLN86 3.9 25.4 1.0
OD1 B:ASN140 3.9 25.1 1.0
C7 C:CLM301 4.0 25.1 1.0
CG B:ASN140 4.0 25.2 1.0
CD1 C:LEU24 4.1 15.6 0.5
C9 C:CLM301 4.3 27.9 1.0
CD2 C:LEU24 4.3 18.1 0.5
C6 C:CLM301 4.5 26.2 1.0
CZ C:PHE19 4.7 19.6 1.0
CE2 C:PHE19 4.7 18.5 1.0
O9B C:CLM301 4.8 33.6 1.0
C10 C:CLM301 4.8 27.5 1.0
C3 C:CLM301 4.9 26.9 1.0
N9 C:CLM301 4.9 32.6 1.0
C11 C:CLM301 4.9 27.7 1.0
CZ B:PHE129 5.0 19.8 1.0

Chlorine binding site 6 out of 6 in 6x7q

Go back to Chlorine Binding Sites List in 6x7q
Chlorine binding site 6 out of 6 in the Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl301

b:45.5
occ:1.00
 CL2 C:CLM301 0.0 45.5 1.0
C1 C:CLM301 1.8 42.2 1.0
C2 C:CLM301 2.6 34.0 1.0
CL1 C:CLM301 2.9 60.8 1.0
O2 C:CLM301 3.0 24.2 1.0
N2 C:CLM301 3.4 27.4 1.0
CB B:ALA99 3.6 16.1 1.0
CE1 B:PHE129 3.7 18.8 1.0
OE1 B:GLN86 3.7 25.4 1.0
CZ B:PHE129 3.8 19.8 1.0
OH C:TYR20 4.2 23.3 1.0
O B:HOH471 4.4 33.1 1.0
CD B:GLN86 4.4 19.2 1.0
ND2 B:ASN140 4.4 26.0 1.0
C3 C:CLM301 4.7 26.9 1.0
CD1 B:PHE129 4.8 18.9 1.0
CD1 B:LEU128 4.8 19.4 1.0
CE2 C:PHE19 4.8 18.5 1.0
CA B:ALA99 4.9 15.8 1.0
CE2 B:PHE97 4.9 14.4 1.0
CE2 B:PHE129 4.9 19.1 1.0
O C:HOH577 5.0 20.4 1.0

Reference:

A.B.Benjamin, L.M.Stunkard, J.Ling, J.N.Nice, J.R.Lohman. Chloramphenicol Acetyltransferase Type III in Complex with Chloramphenicol and Acetyl-Oxa(Dethia)-Coa To Be Published.
Page generated: Mon Jul 29 17:06:15 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy