Chlorine in PDB 6xcf: Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59
Enzymatic activity of Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59
All present enzymatic activity of Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59:
3.4.24.69;
3.4.24.69;
Protein crystallography data
The structure of Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59, PDB code: 6xcf
was solved by
M.A.Tararina,
K.N.Allen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 39.29 / 1.68 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 49.339, 66.245, 64.057, 90.00, 98.52, 90.00 |
| R / Rfree (%) | 15.9 / 19.9 |
Other elements in 6xcf:
The structure of Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59 also contains other interesting chemical elements:
| Zinc | (Zn) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59
(pdb code 6xcf). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59, PDB code: 6xcf:
Jump to Chlorine binding site number: 1; 2;
In total 2 binding sites of Chlorine where determined in the Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59, PDB code: 6xcf:
Jump to Chlorine binding site number: 1; 2;
Chlorine binding site 1 out of 2 in 6xcf
Go back to
Chlorine Binding Sites List in 6xcf
Chlorine binding site 1 out
of 2 in the Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59 within 5.0Å range:
|
Chlorine binding site 2 out of 2 in 6xcf
Go back to
Chlorine Binding Sites List in 6xcf
Chlorine binding site 2 out
of 2 in the Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Structure of the C. Botulinum Neurotoxin Serotype A Light Chain Protease in Complex with Noncovalent Inhibitor 59 within 5.0Å range:
|
Reference:
L.Lin,
M.E.Olson,
T.Sugane,
L.D.Turner,
M.A.Tararina,
A.L.Nielsen,
E.K.Kurbanov,
S.Pellett,
E.A.Johnson,
S.M.Cohen,
K.N.Allen,
K.D.Janda.
Catch and Anchor Approach to Combat Both Toxicity and Longevity of Botulinum Toxin A. J.Med.Chem. V. 63 11100 2020.
ISSN: ISSN 0022-2623
PubMed: 32886509
DOI: 10.1021/ACS.JMEDCHEM.0C01006
Page generated: Sat Dec 12 14:35:22 2020
ISSN: ISSN 0022-2623
PubMed: 32886509
DOI: 10.1021/ACS.JMEDCHEM.0C01006
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