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Chlorine in PDB 6xdb: Crystal Structure of IRE1A in Complex with G-6904Enzymatic activity of Crystal Structure of IRE1A in Complex with G-6904
All present enzymatic activity of Crystal Structure of IRE1A in Complex with G-6904:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of IRE1A in Complex with G-6904, PDB code: 6xdb
was solved by
H.A.Wallweber,
W.Weiru,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6xdb:
The structure of Crystal Structure of IRE1A in Complex with G-6904 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of IRE1A in Complex with G-6904
(pdb code 6xdb). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of IRE1A in Complex with G-6904, PDB code: 6xdb: Chlorine binding site 1 out of 1 in 6xdbGo back to Chlorine Binding Sites List in 6xdb
Chlorine binding site 1 out
of 1 in the Crystal Structure of IRE1A in Complex with G-6904
Mono view Stereo pair view
Reference:
R.E.Beveridge,
H.A.Wallweber,
A.Ashkenazi,
M.Beresini,
K.R.Clark,
P.Gibbons,
E.Ghiro,
S.Kaufman,
A.Larivee,
M.Leblanc,
J.P.Leclerc,
A.Lemire,
C.Ly,
J.Rudolph,
J.B.Schwarz,
S.Srivastava,
W.Wang,
L.Zhao,
M.G.Braun.
Identification of Braf-Sparing Amino-Thienopyrimidines with Potent IRE1 Alpha Inhibitory Activity. Acs Med.Chem.Lett. V. 11 2389 2020.
Page generated: Sat Jul 10 12:24:18 2021
ISSN: ISSN 1948-5875 PubMed: 33335661 DOI: 10.1021/ACSMEDCHEMLETT.0C00344 |
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