Atomistry » Chlorine » PDB 6xi7-6xqv » 6xk7
Atomistry »
  Chlorine »
    PDB 6xi7-6xqv »
      6xk7 »

Chlorine in PDB 6xk7: Nitric Oxide Synthase From Bacillus Subtilis in Complex with 7-((3-(2- (6-Aminopyridin-2-Yl)Ethyl)Phenoxy)Methyl)Quinolin-2-Amine

Enzymatic activity of Nitric Oxide Synthase From Bacillus Subtilis in Complex with 7-((3-(2- (6-Aminopyridin-2-Yl)Ethyl)Phenoxy)Methyl)Quinolin-2-Amine

All present enzymatic activity of Nitric Oxide Synthase From Bacillus Subtilis in Complex with 7-((3-(2- (6-Aminopyridin-2-Yl)Ethyl)Phenoxy)Methyl)Quinolin-2-Amine:
1.14.14.47;

Protein crystallography data

The structure of Nitric Oxide Synthase From Bacillus Subtilis in Complex with 7-((3-(2- (6-Aminopyridin-2-Yl)Ethyl)Phenoxy)Methyl)Quinolin-2-Amine, PDB code: 6xk7 was solved by M.C.Lewis, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.64 / 1.85
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 80.887, 94.82, 61.924, 90, 90, 90
R / Rfree (%) 19.6 / 24.2

Other elements in 6xk7:

The structure of Nitric Oxide Synthase From Bacillus Subtilis in Complex with 7-((3-(2- (6-Aminopyridin-2-Yl)Ethyl)Phenoxy)Methyl)Quinolin-2-Amine also contains other interesting chemical elements:

Iron (Fe) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Nitric Oxide Synthase From Bacillus Subtilis in Complex with 7-((3-(2- (6-Aminopyridin-2-Yl)Ethyl)Phenoxy)Methyl)Quinolin-2-Amine (pdb code 6xk7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Nitric Oxide Synthase From Bacillus Subtilis in Complex with 7-((3-(2- (6-Aminopyridin-2-Yl)Ethyl)Phenoxy)Methyl)Quinolin-2-Amine, PDB code: 6xk7:

Chlorine binding site 1 out of 1 in 6xk7

Go back to Chlorine Binding Sites List in 6xk7
Chlorine binding site 1 out of 1 in the Nitric Oxide Synthase From Bacillus Subtilis in Complex with 7-((3-(2- (6-Aminopyridin-2-Yl)Ethyl)Phenoxy)Methyl)Quinolin-2-Amine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Nitric Oxide Synthase From Bacillus Subtilis in Complex with 7-((3-(2- (6-Aminopyridin-2-Yl)Ethyl)Phenoxy)Methyl)Quinolin-2-Amine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl903

b:44.1
occ:1.00
 OH A:TYR239 3.0 37.2 1.0
O A:HOH1089 3.1 44.7 1.0
ND2 A:ASN248 3.2 34.8 1.0
NE2 A:GLN129 3.3 41.5 1.0
O A:HOH1038 3.3 38.5 1.0
CE1 A:TYR239 3.5 30.8 1.0
CZ A:TYR239 3.7 35.2 1.0
OD1 A:ASN248 3.9 36.6 1.0
CG A:ASN248 4.0 35.8 1.0
OH A:TYR213 4.1 35.1 1.0
CD A:GLN129 4.2 40.6 1.0
OE1 A:GLN129 4.2 38.7 1.0
O A:HOH1104 4.6 48.8 1.0
CD1 A:TYR239 4.7 33.7 1.0
CB A:PRO216 4.8 35.2 1.0
NE1 A:TRP212 4.9 31.4 1.0
OE1 A:GLU243 5.0 36.3 1.0

Reference:

M.C.Lewis, T.L.Poulos. Selective Anti-Mrsa Inhibitors Targeting Nitric Oxide Synthase To Be Published.
Page generated: Mon Jul 29 17:15:57 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy