Chlorine in PDB 6xkm: Room Temperature Structure of Sars-Cov-2 NSP10/NSP16 Methyltransferase in A Complex with Sam Determined By Fixed-Target Serial Crystallography

The structure of Room Temperature Structure of Sars-Cov-2 NSP10/NSP16 Methyltransferase in A Complex with Sam Determined By Fixed-Target Serial Crystallography, PDB code: 6xkm was solved by M.Wilamowski, D.A.Sherrell, G.Minasov, Y.Kim, L.Shuvalova, A.Lavens, R.Chard, M.Rosas-Lemus, N.Maltseva, R.Jedrzejczak, K.Michalska, K.J.F.Satchell, A.Joachimiak, Center For Structural Genomics Ofinfectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.57 / 2.25
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	170.410, 170.410, 52.631, 90.00, 90.00, 120.00
R / Rfree (%)	20.7 / 21.3

The structure of Room Temperature Structure of Sars-Cov-2 NSP10/NSP16 Methyltransferase in A Complex with Sam Determined By Fixed-Target Serial Crystallography also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Chlorine atom in the Room Temperature Structure of Sars-Cov-2 NSP10/NSP16 Methyltransferase in A Complex with Sam Determined By Fixed-Target Serial Crystallography (pdb code 6xkm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Room Temperature Structure of Sars-Cov-2 NSP10/NSP16 Methyltransferase in A Complex with Sam Determined By Fixed-Target Serial Crystallography, PDB code: 6xkm:

Chlorine binding site 1 out of 1 in the Room Temperature Structure of Sars-Cov-2 NSP10/NSP16 Methyltransferase in A Complex with Sam Determined By Fixed-Target Serial Crystallography


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Room Temperature Structure of Sars-Cov-2 NSP10/NSP16 Methyltransferase in A Complex with Sam Determined By Fixed-Target Serial Crystallography within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7101 b:58.2 occ:1.00 OG1 A:THR172 2.9 17.0 1.0 ND1 A:HIS174 3.5 24.1 1.0 CB A:THR172 3.5 16.4 1.0 OH A:TYR132 3.5 29.3 1.0 N A:HIS174 3.6 20.2 1.0 CB A:HIS174 3.7 22.7 1.0 O A:HOH7245 3.9 30.4 1.0 CG A:HIS174 4.0 24.0 1.0 CB A:LYS137 4.1 64.0 1.0 CA A:HIS174 4.1 21.2 1.0 CE1 A:TYR132 4.2 26.9 1.0 N A:GLU173 4.2 18.0 1.0 N A:SER175 4.2 19.2 1.0 CG2 A:THR172 4.2 15.8 1.0 CD A:LYS137 4.3 73.0 1.0 CZ A:TYR132 4.3 28.1 1.0 OG A:SER202 4.4 19.9 1.0 CG A:LYS137 4.4 69.0 1.0 CA A:LYS137 4.6 61.3 1.0 C A:HIS174 4.6 20.5 1.0 CE1 A:HIS174 4.6 25.6 1.0 C A:GLU173 4.7 19.8 1.0 C A:THR172 4.7 17.0 1.0 CA A:THR172 4.7 16.0 1.0 OG1 A:THR136 4.7 49.2 1.0 CB A:GLU173 4.7 20.3 1.0 CA A:GLU173 4.8 19.2 1.0 N A:LYS137 4.9 57.7 1.0

M.Wilamowski, D.A.Sherrell, G.Minasov, Y.Kim, L.Shuvalova, A.Lavens, R.Chard, M.Rosas-Lemus, N.Maltseva, R.Jedrzejczak, K.Michalska, K.J.F.Satchell, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). Room Temperature Structure of Sars-Cov-2 NSP10/NSP16 Methyltransferase in A Complex with Sam Determined By Fixed-Target Serial Crystallography To Be Published.