Chlorine in PDB 6xmx: Cryo-Em Structure of BCL6 Bound to Bi-3802
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Cryo-Em Structure of BCL6 Bound to Bi-3802
(pdb code 6xmx). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the
Cryo-Em Structure of BCL6 Bound to Bi-3802, PDB code: 6xmx:
Jump to Chlorine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Chlorine binding site 1 out
of 8 in 6xmx
Go back to
Chlorine Binding Sites List in 6xmx
Chlorine binding site 1 out
of 8 in the Cryo-Em Structure of BCL6 Bound to Bi-3802
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Cryo-Em Structure of BCL6 Bound to Bi-3802 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Cl401
b:16.1
occ:1.00
|
CL1
|
A:U52401
|
0.0
|
16.1
|
1.0
|
|
C27
|
A:U52401
|
1.7
|
16.1
|
1.0
|
|
HD11
|
B:LEU25
|
2.6
|
15.4
|
1.0
|
|
C26
|
A:U52401
|
2.6
|
16.1
|
1.0
|
|
H17
|
A:U52401
|
2.7
|
16.1
|
1.0
|
|
HA
|
A:ALA52
|
2.7
|
14.9
|
1.0
|
|
C22
|
A:U52401
|
2.7
|
16.1
|
1.0
|
|
HB3
|
A:MET51
|
2.7
|
16.3
|
1.0
|
|
HD21
|
B:LEU25
|
2.8
|
15.4
|
1.0
|
|
H8
|
A:U52401
|
2.8
|
16.1
|
1.0
|
|
HG
|
B:LEU25
|
2.8
|
15.4
|
1.0
|
|
O
|
A:MET51
|
3.0
|
16.3
|
1.0
|
|
C
|
A:MET51
|
3.0
|
16.3
|
1.0
|
|
HB3
|
B:ASN21
|
3.0
|
15.0
|
1.0
|
|
N19
|
A:U52401
|
3.1
|
16.1
|
1.0
|
|
CD1
|
B:LEU25
|
3.1
|
15.4
|
1.0
|
|
N
|
A:ALA52
|
3.2
|
14.9
|
1.0
|
|
HD12
|
B:LEU25
|
3.2
|
15.4
|
1.0
|
|
CG
|
B:LEU25
|
3.3
|
15.4
|
1.0
|
|
HD1
|
A:TYR58
|
3.3
|
16.6
|
1.0
|
|
HB2
|
A:MET51
|
3.3
|
16.3
|
1.0
|
|
CB
|
A:MET51
|
3.4
|
16.3
|
1.0
|
|
CA
|
A:ALA52
|
3.4
|
14.9
|
1.0
|
|
CD2
|
B:LEU25
|
3.4
|
15.4
|
1.0
|
|
H
|
A:ALA52
|
3.7
|
14.9
|
1.0
|
|
CA
|
A:MET51
|
3.8
|
16.3
|
1.0
|
|
N25
|
A:U52401
|
3.9
|
16.1
|
1.0
|
|
O
|
B:ASN21
|
3.9
|
15.0
|
1.0
|
|
N23
|
A:U52401
|
3.9
|
16.1
|
1.0
|
|
CB
|
B:ASN21
|
4.0
|
15.0
|
1.0
|
|
CD1
|
A:TYR58
|
4.0
|
16.6
|
1.0
|
|
HD23
|
B:LEU25
|
4.0
|
15.4
|
1.0
|
|
HD13
|
B:LEU25
|
4.0
|
15.4
|
1.0
|
|
HB2
|
A:ALA52
|
4.1
|
14.9
|
1.0
|
|
HD22
|
B:LEU25
|
4.1
|
15.4
|
1.0
|
|
HE2
|
A:MET51
|
4.2
|
16.3
|
1.0
|
|
HA
|
A:MET51
|
4.3
|
16.3
|
1.0
|
|
HB2
|
A:TYR58
|
4.3
|
16.6
|
1.0
|
|
CB
|
A:ALA52
|
4.3
|
14.9
|
1.0
|
|
C
|
B:ASN21
|
4.4
|
15.0
|
1.0
|
|
C24
|
A:U52401
|
4.4
|
16.1
|
1.0
|
|
HE1
|
A:TYR58
|
4.4
|
16.6
|
1.0
|
|
HB2
|
B:ASN21
|
4.4
|
15.0
|
1.0
|
|
C
|
A:ALA52
|
4.5
|
14.9
|
1.0
|
|
C18
|
A:U52401
|
4.5
|
16.1
|
1.0
|
|
CE1
|
A:TYR58
|
4.6
|
16.6
|
1.0
|
|
CG
|
A:MET51
|
4.7
|
16.3
|
1.0
|
|
CA
|
B:ASN21
|
4.7
|
15.0
|
1.0
|
|
CB
|
B:LEU25
|
4.7
|
15.4
|
1.0
|
|
CG
|
B:ASN21
|
4.8
|
15.0
|
1.0
|
|
O
|
A:THR48
|
4.8
|
16.2
|
1.0
|
|
HB1
|
A:ALA52
|
4.8
|
14.9
|
1.0
|
|
HA
|
B:LEU22
|
4.8
|
14.9
|
1.0
|
|
HA
|
B:ASN21
|
4.9
|
15.0
|
1.0
|
|
O
|
A:ALA52
|
4.9
|
14.9
|
1.0
|
|
CG
|
A:TYR58
|
4.9
|
16.6
|
1.0
|
|
H7
|
A:U52401
|
4.9
|
16.1
|
1.0
|
|
N
|
A:MET51
|
5.0
|
16.3
|
1.0
|
|
HB2
|
B:LEU25
|
5.0
|
15.4
|
1.0
|
|
Chlorine binding site 2 out
of 8 in 6xmx
Go back to
Chlorine Binding Sites List in 6xmx
Chlorine binding site 2 out
of 8 in the Cryo-Em Structure of BCL6 Bound to Bi-3802
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Cryo-Em Structure of BCL6 Bound to Bi-3802 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Cl401
b:19.6
occ:1.00
|
CL1
|
B:U52401
|
0.0
|
19.6
|
1.0
|
|
C27
|
B:U52401
|
1.7
|
19.6
|
1.0
|
|
HB3
|
A:ASN21
|
2.4
|
18.1
|
1.0
|
|
C26
|
B:U52401
|
2.6
|
19.6
|
1.0
|
|
H17
|
B:U52401
|
2.7
|
19.6
|
1.0
|
|
HA
|
B:ALA52
|
2.7
|
16.7
|
1.0
|
|
C22
|
B:U52401
|
2.7
|
19.6
|
1.0
|
|
HB3
|
B:MET51
|
2.7
|
17.2
|
1.0
|
|
H8
|
B:U52401
|
2.8
|
19.6
|
1.0
|
|
HD11
|
A:LEU25
|
2.9
|
17.7
|
1.0
|
|
O
|
B:MET51
|
3.0
|
17.2
|
1.0
|
|
C
|
B:MET51
|
3.0
|
17.2
|
1.0
|
|
N19
|
B:U52401
|
3.1
|
19.6
|
1.0
|
|
HG
|
A:LEU25
|
3.1
|
17.7
|
1.0
|
|
N
|
B:ALA52
|
3.2
|
16.7
|
1.0
|
|
CB
|
A:ASN21
|
3.3
|
18.1
|
1.0
|
|
HD1
|
B:TYR58
|
3.3
|
17.9
|
1.0
|
|
HB2
|
B:MET51
|
3.3
|
17.2
|
1.0
|
|
CB
|
B:MET51
|
3.4
|
17.2
|
1.0
|
|
HD21
|
A:LEU25
|
3.4
|
17.7
|
1.0
|
|
CA
|
B:ALA52
|
3.4
|
16.7
|
1.0
|
|
CD1
|
A:LEU25
|
3.6
|
17.7
|
1.0
|
|
O
|
A:ASN21
|
3.7
|
18.1
|
1.0
|
|
CG
|
A:LEU25
|
3.7
|
17.7
|
1.0
|
|
H
|
B:ALA52
|
3.7
|
16.7
|
1.0
|
|
HB2
|
A:ASN21
|
3.8
|
18.1
|
1.0
|
|
CA
|
B:MET51
|
3.8
|
17.2
|
1.0
|
|
HD12
|
A:LEU25
|
3.9
|
17.7
|
1.0
|
|
N25
|
B:U52401
|
3.9
|
19.6
|
1.0
|
|
C
|
A:ASN21
|
3.9
|
18.1
|
1.0
|
|
N23
|
B:U52401
|
3.9
|
19.6
|
1.0
|
|
CG
|
A:ASN21
|
4.0
|
18.1
|
1.0
|
|
CD1
|
B:TYR58
|
4.0
|
17.9
|
1.0
|
|
CD2
|
A:LEU25
|
4.0
|
17.7
|
1.0
|
|
HB2
|
B:ALA52
|
4.1
|
16.7
|
1.0
|
|
CA
|
A:ASN21
|
4.1
|
18.1
|
1.0
|
|
HE2
|
B:MET51
|
4.2
|
17.2
|
1.0
|
|
HB2
|
B:TYR58
|
4.3
|
17.9
|
1.0
|
|
HA
|
B:MET51
|
4.3
|
17.2
|
1.0
|
|
HA
|
A:ASN21
|
4.3
|
18.1
|
1.0
|
|
CB
|
B:ALA52
|
4.3
|
16.7
|
1.0
|
|
HE1
|
B:TYR58
|
4.4
|
17.9
|
1.0
|
|
C24
|
B:U52401
|
4.4
|
19.6
|
1.0
|
|
HD13
|
A:LEU25
|
4.4
|
17.7
|
1.0
|
|
C18
|
B:U52401
|
4.5
|
19.6
|
1.0
|
|
C
|
B:ALA52
|
4.5
|
16.7
|
1.0
|
|
OD1
|
A:ASN21
|
4.5
|
18.1
|
1.0
|
|
HD23
|
A:LEU25
|
4.6
|
17.7
|
1.0
|
|
CE1
|
B:TYR58
|
4.6
|
17.9
|
1.0
|
|
CG
|
B:MET51
|
4.7
|
17.2
|
1.0
|
|
ND2
|
A:ASN21
|
4.7
|
18.1
|
1.0
|
|
HD22
|
A:ASN21
|
4.7
|
18.1
|
1.0
|
|
HD22
|
A:LEU25
|
4.7
|
17.7
|
1.0
|
|
N
|
A:LEU22
|
4.7
|
17.0
|
1.0
|
|
HA
|
A:LEU22
|
4.7
|
17.0
|
1.0
|
|
HB1
|
B:ALA52
|
4.7
|
16.7
|
1.0
|
|
O
|
B:THR48
|
4.8
|
16.5
|
1.0
|
|
O
|
B:ALA52
|
4.9
|
16.7
|
1.0
|
|
CG
|
B:TYR58
|
4.9
|
17.9
|
1.0
|
|
H7
|
B:U52401
|
4.9
|
19.6
|
1.0
|
|
N
|
B:MET51
|
4.9
|
17.2
|
1.0
|
|
HG2
|
B:MET51
|
5.0
|
17.2
|
1.0
|
|
CB
|
B:TYR58
|
5.0
|
17.9
|
1.0
|
|
Chlorine binding site 3 out
of 8 in 6xmx
Go back to
Chlorine Binding Sites List in 6xmx
Chlorine binding site 3 out
of 8 in the Cryo-Em Structure of BCL6 Bound to Bi-3802
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of Cryo-Em Structure of BCL6 Bound to Bi-3802 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl401
b:26.6
occ:1.00
|
CL1
|
C:U52401
|
0.0
|
26.6
|
1.0
|
|
C27
|
C:U52401
|
1.7
|
26.6
|
1.0
|
|
HD11
|
D:LEU25
|
2.5
|
25.9
|
1.0
|
|
C26
|
C:U52401
|
2.6
|
26.6
|
1.0
|
|
HD21
|
D:LEU25
|
2.7
|
25.9
|
1.0
|
|
H17
|
C:U52401
|
2.7
|
26.6
|
1.0
|
|
C22
|
C:U52401
|
2.7
|
26.6
|
1.0
|
|
HB3
|
C:MET51
|
2.7
|
28.3
|
1.0
|
|
HA
|
C:ALA52
|
2.7
|
26.6
|
1.0
|
|
H8
|
C:U52401
|
2.8
|
26.6
|
1.0
|
|
HG
|
D:LEU25
|
2.8
|
25.9
|
1.0
|
|
O
|
C:MET51
|
3.0
|
28.3
|
1.0
|
|
C
|
C:MET51
|
3.0
|
28.3
|
1.0
|
|
N19
|
C:U52401
|
3.1
|
26.6
|
1.0
|
|
CD1
|
D:LEU25
|
3.1
|
25.9
|
1.0
|
|
HB3
|
D:ASN21
|
3.2
|
25.7
|
1.0
|
|
CG
|
D:LEU25
|
3.2
|
25.9
|
1.0
|
|
N
|
C:ALA52
|
3.2
|
26.6
|
1.0
|
|
HD12
|
D:LEU25
|
3.3
|
25.9
|
1.0
|
|
HD1
|
C:TYR58
|
3.3
|
28.0
|
1.0
|
|
HB2
|
C:MET51
|
3.3
|
28.3
|
1.0
|
|
CD2
|
D:LEU25
|
3.3
|
25.9
|
1.0
|
|
CB
|
C:MET51
|
3.3
|
28.3
|
1.0
|
|
CA
|
C:ALA52
|
3.4
|
26.6
|
1.0
|
|
H
|
C:ALA52
|
3.7
|
26.6
|
1.0
|
|
CA
|
C:MET51
|
3.8
|
28.3
|
1.0
|
|
HD23
|
D:LEU25
|
3.8
|
25.9
|
1.0
|
|
N25
|
C:U52401
|
3.9
|
26.6
|
1.0
|
|
N23
|
C:U52401
|
3.9
|
26.6
|
1.0
|
|
O
|
D:ASN21
|
4.0
|
25.7
|
1.0
|
|
HD13
|
D:LEU25
|
4.0
|
25.9
|
1.0
|
|
CD1
|
C:TYR58
|
4.0
|
28.0
|
1.0
|
|
HB2
|
C:ALA52
|
4.1
|
26.6
|
1.0
|
|
HD22
|
D:LEU25
|
4.1
|
25.9
|
1.0
|
|
CB
|
D:ASN21
|
4.1
|
25.7
|
1.0
|
|
HB2
|
C:TYR58
|
4.3
|
28.0
|
1.0
|
|
HA
|
C:MET51
|
4.3
|
28.3
|
1.0
|
|
HE2
|
C:MET51
|
4.3
|
28.3
|
1.0
|
|
CB
|
C:ALA52
|
4.3
|
26.6
|
1.0
|
|
C24
|
C:U52401
|
4.4
|
26.6
|
1.0
|
|
HE1
|
C:TYR58
|
4.4
|
28.0
|
1.0
|
|
C
|
D:ASN21
|
4.4
|
25.7
|
1.0
|
|
C
|
C:ALA52
|
4.5
|
26.6
|
1.0
|
|
C18
|
C:U52401
|
4.5
|
26.6
|
1.0
|
|
HB2
|
D:ASN21
|
4.6
|
25.7
|
1.0
|
|
CE1
|
C:TYR58
|
4.6
|
28.0
|
1.0
|
|
CG
|
C:MET51
|
4.7
|
28.3
|
1.0
|
|
CB
|
D:LEU25
|
4.7
|
25.9
|
1.0
|
|
O
|
C:THR48
|
4.8
|
28.9
|
1.0
|
|
CA
|
D:ASN21
|
4.8
|
25.7
|
1.0
|
|
HB1
|
C:ALA52
|
4.8
|
26.6
|
1.0
|
|
CG
|
D:ASN21
|
4.9
|
25.7
|
1.0
|
|
O
|
C:ALA52
|
4.9
|
26.6
|
1.0
|
|
CG
|
C:TYR58
|
4.9
|
28.0
|
1.0
|
|
HA
|
D:LEU22
|
4.9
|
26.3
|
1.0
|
|
HA
|
D:ASN21
|
4.9
|
25.7
|
1.0
|
|
N
|
C:MET51
|
4.9
|
28.3
|
1.0
|
|
H7
|
C:U52401
|
4.9
|
26.6
|
1.0
|
|
HB2
|
D:LEU25
|
4.9
|
25.9
|
1.0
|
|
HG2
|
C:MET51
|
5.0
|
28.3
|
1.0
|
|
CB
|
C:TYR58
|
5.0
|
28.0
|
1.0
|
|
Chlorine binding site 4 out
of 8 in 6xmx
Go back to
Chlorine Binding Sites List in 6xmx
Chlorine binding site 4 out
of 8 in the Cryo-Em Structure of BCL6 Bound to Bi-3802
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 4 of Cryo-Em Structure of BCL6 Bound to Bi-3802 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Cl401
b:31.2
occ:1.00
|
CL1
|
D:U52401
|
0.0
|
31.2
|
1.0
|
|
C27
|
D:U52401
|
1.7
|
31.2
|
1.0
|
|
C26
|
D:U52401
|
2.6
|
31.2
|
1.0
|
|
HB3
|
C:ASN21
|
2.7
|
31.6
|
1.0
|
|
H17
|
D:U52401
|
2.7
|
31.2
|
1.0
|
|
C22
|
D:U52401
|
2.7
|
31.2
|
1.0
|
|
HA
|
D:ALA52
|
2.7
|
30.3
|
1.0
|
|
HB3
|
D:MET51
|
2.7
|
30.1
|
1.0
|
|
H8
|
D:U52401
|
2.8
|
31.2
|
1.0
|
|
HD11
|
C:LEU25
|
3.0
|
30.5
|
1.0
|
|
O
|
D:MET51
|
3.0
|
30.1
|
1.0
|
|
C
|
D:MET51
|
3.0
|
30.1
|
1.0
|
|
N19
|
D:U52401
|
3.1
|
31.2
|
1.0
|
|
N
|
D:ALA52
|
3.2
|
30.3
|
1.0
|
|
HD1
|
D:TYR58
|
3.3
|
30.4
|
1.0
|
|
HG
|
C:LEU25
|
3.3
|
30.5
|
1.0
|
|
HB2
|
D:MET51
|
3.3
|
30.1
|
1.0
|
|
CB
|
D:MET51
|
3.4
|
30.1
|
1.0
|
|
HD21
|
C:LEU25
|
3.4
|
30.5
|
1.0
|
|
CA
|
D:ALA52
|
3.4
|
30.3
|
1.0
|
|
CB
|
C:ASN21
|
3.6
|
31.6
|
1.0
|
|
CD1
|
C:LEU25
|
3.7
|
30.5
|
1.0
|
|
H
|
D:ALA52
|
3.7
|
30.3
|
1.0
|
|
CA
|
D:MET51
|
3.8
|
30.1
|
1.0
|
|
CG
|
C:LEU25
|
3.8
|
30.5
|
1.0
|
|
N25
|
D:U52401
|
3.9
|
31.2
|
1.0
|
|
HD12
|
C:LEU25
|
3.9
|
30.5
|
1.0
|
|
N23
|
D:U52401
|
3.9
|
31.2
|
1.0
|
|
CD1
|
D:TYR58
|
4.0
|
30.4
|
1.0
|
|
HB2
|
C:ASN21
|
4.0
|
31.6
|
1.0
|
|
O
|
C:ASN21
|
4.0
|
31.6
|
1.0
|
|
CD2
|
C:LEU25
|
4.1
|
30.5
|
1.0
|
|
HB2
|
D:ALA52
|
4.1
|
30.3
|
1.0
|
|
HE2
|
D:MET51
|
4.2
|
30.1
|
1.0
|
|
HB2
|
D:TYR58
|
4.3
|
30.4
|
1.0
|
|
CG
|
C:ASN21
|
4.3
|
31.6
|
1.0
|
|
HA
|
D:MET51
|
4.3
|
30.1
|
1.0
|
|
C
|
C:ASN21
|
4.3
|
31.6
|
1.0
|
|
CB
|
D:ALA52
|
4.3
|
30.3
|
1.0
|
|
C24
|
D:U52401
|
4.4
|
31.2
|
1.0
|
|
HE1
|
D:TYR58
|
4.4
|
30.4
|
1.0
|
|
C18
|
D:U52401
|
4.5
|
31.2
|
1.0
|
|
C
|
D:ALA52
|
4.5
|
30.3
|
1.0
|
|
CA
|
C:ASN21
|
4.5
|
31.6
|
1.0
|
|
HD13
|
C:LEU25
|
4.5
|
30.5
|
1.0
|
|
HD23
|
C:LEU25
|
4.6
|
30.5
|
1.0
|
|
CE1
|
D:TYR58
|
4.6
|
30.4
|
1.0
|
|
HA
|
C:ASN21
|
4.7
|
31.6
|
1.0
|
|
CG
|
D:MET51
|
4.7
|
30.1
|
1.0
|
|
HB1
|
D:ALA52
|
4.7
|
30.3
|
1.0
|
|
OD1
|
C:ASN21
|
4.7
|
31.6
|
1.0
|
|
HD22
|
C:LEU25
|
4.8
|
30.5
|
1.0
|
|
O
|
D:THR48
|
4.8
|
29.4
|
1.0
|
|
HD22
|
C:ASN21
|
4.8
|
31.6
|
1.0
|
|
ND2
|
C:ASN21
|
4.8
|
31.6
|
1.0
|
|
O
|
D:ALA52
|
4.9
|
30.3
|
1.0
|
|
CG
|
D:TYR58
|
4.9
|
30.4
|
1.0
|
|
H7
|
D:U52401
|
4.9
|
31.2
|
1.0
|
|
N
|
D:MET51
|
5.0
|
30.1
|
1.0
|
|
HG2
|
D:MET51
|
5.0
|
30.1
|
1.0
|
|
Chlorine binding site 5 out
of 8 in 6xmx
Go back to
Chlorine Binding Sites List in 6xmx
Chlorine binding site 5 out
of 8 in the Cryo-Em Structure of BCL6 Bound to Bi-3802
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 5 of Cryo-Em Structure of BCL6 Bound to Bi-3802 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Cl401
b:17.0
occ:1.00
|
CL1
|
E:U52401
|
0.0
|
17.0
|
1.0
|
|
C27
|
E:U52401
|
1.7
|
17.0
|
1.0
|
|
HB3
|
F:ASN21
|
2.5
|
15.5
|
1.0
|
|
C26
|
E:U52401
|
2.6
|
17.0
|
1.0
|
|
H17
|
E:U52401
|
2.7
|
17.0
|
1.0
|
|
HB3
|
E:MET51
|
2.7
|
14.9
|
1.0
|
|
C22
|
E:U52401
|
2.7
|
17.0
|
1.0
|
|
HA
|
E:ALA52
|
2.7
|
14.5
|
1.0
|
|
H8
|
E:U52401
|
2.8
|
17.0
|
1.0
|
|
O
|
E:MET51
|
3.0
|
14.9
|
1.0
|
|
C
|
E:MET51
|
3.0
|
14.9
|
1.0
|
|
HD11
|
F:LEU25
|
3.0
|
15.8
|
1.0
|
|
N19
|
E:U52401
|
3.1
|
17.0
|
1.0
|
|
HG
|
F:LEU25
|
3.2
|
15.8
|
1.0
|
|
N
|
E:ALA52
|
3.2
|
14.5
|
1.0
|
|
HD1
|
E:TYR58
|
3.3
|
15.3
|
1.0
|
|
CB
|
E:MET51
|
3.4
|
14.9
|
1.0
|
|
HD21
|
F:LEU25
|
3.4
|
15.8
|
1.0
|
|
HB2
|
E:MET51
|
3.4
|
14.9
|
1.0
|
|
CA
|
E:ALA52
|
3.4
|
14.5
|
1.0
|
|
CB
|
F:ASN21
|
3.4
|
15.5
|
1.0
|
|
CD1
|
F:LEU25
|
3.7
|
15.8
|
1.0
|
|
H
|
E:ALA52
|
3.7
|
14.5
|
1.0
|
|
CG
|
F:LEU25
|
3.8
|
15.8
|
1.0
|
|
CA
|
E:MET51
|
3.8
|
14.9
|
1.0
|
|
O
|
F:ASN21
|
3.8
|
15.5
|
1.0
|
|
HB2
|
F:ASN21
|
3.8
|
15.5
|
1.0
|
|
N25
|
E:U52401
|
3.9
|
17.0
|
1.0
|
|
HD12
|
F:LEU25
|
3.9
|
15.8
|
1.0
|
|
N23
|
E:U52401
|
3.9
|
17.0
|
1.0
|
|
CD1
|
E:TYR58
|
4.0
|
15.3
|
1.0
|
|
CD2
|
F:LEU25
|
4.0
|
15.8
|
1.0
|
|
CG
|
F:ASN21
|
4.1
|
15.5
|
1.0
|
|
HB2
|
E:ALA52
|
4.1
|
14.5
|
1.0
|
|
C
|
F:ASN21
|
4.1
|
15.5
|
1.0
|
|
HE2
|
E:MET51
|
4.2
|
14.9
|
1.0
|
|
CA
|
F:ASN21
|
4.2
|
15.5
|
1.0
|
|
HA
|
E:MET51
|
4.3
|
14.9
|
1.0
|
|
HB2
|
E:TYR58
|
4.3
|
15.3
|
1.0
|
|
CB
|
E:ALA52
|
4.3
|
14.5
|
1.0
|
|
C24
|
E:U52401
|
4.4
|
17.0
|
1.0
|
|
HE1
|
E:TYR58
|
4.4
|
15.3
|
1.0
|
|
HA
|
F:ASN21
|
4.4
|
15.5
|
1.0
|
|
C18
|
E:U52401
|
4.5
|
17.0
|
1.0
|
|
C
|
E:ALA52
|
4.5
|
14.5
|
1.0
|
|
OD1
|
F:ASN21
|
4.5
|
15.5
|
1.0
|
|
HD13
|
F:LEU25
|
4.5
|
15.8
|
1.0
|
|
HD23
|
F:LEU25
|
4.6
|
15.8
|
1.0
|
|
CE1
|
E:TYR58
|
4.6
|
15.3
|
1.0
|
|
CG
|
E:MET51
|
4.7
|
14.9
|
1.0
|
|
ND2
|
F:ASN21
|
4.7
|
15.5
|
1.0
|
|
HD22
|
F:LEU25
|
4.7
|
15.8
|
1.0
|
|
HD22
|
F:ASN21
|
4.7
|
15.5
|
1.0
|
|
O
|
E:THR48
|
4.8
|
14.7
|
1.0
|
|
HB1
|
E:ALA52
|
4.8
|
14.5
|
1.0
|
|
O
|
E:ALA52
|
4.9
|
14.5
|
1.0
|
|
N
|
F:LEU22
|
4.9
|
15.3
|
1.0
|
|
CG
|
E:TYR58
|
4.9
|
15.3
|
1.0
|
|
HA
|
F:LEU22
|
4.9
|
15.3
|
1.0
|
|
H7
|
E:U52401
|
4.9
|
17.0
|
1.0
|
|
N
|
E:MET51
|
4.9
|
14.9
|
1.0
|
|
HG2
|
E:MET51
|
5.0
|
14.9
|
1.0
|
|
CB
|
E:TYR58
|
5.0
|
15.3
|
1.0
|
|
Chlorine binding site 6 out
of 8 in 6xmx
Go back to
Chlorine Binding Sites List in 6xmx
Chlorine binding site 6 out
of 8 in the Cryo-Em Structure of BCL6 Bound to Bi-3802
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 6 of Cryo-Em Structure of BCL6 Bound to Bi-3802 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Cl401
b:16.8
occ:1.00
|
CL1
|
F:U52401
|
0.0
|
16.8
|
1.0
|
|
C27
|
F:U52401
|
1.7
|
16.8
|
1.0
|
|
HD11
|
E:LEU25
|
2.6
|
14.5
|
1.0
|
|
HD21
|
E:LEU25
|
2.6
|
14.5
|
1.0
|
|
C26
|
F:U52401
|
2.6
|
16.8
|
1.0
|
|
C22
|
F:U52401
|
2.7
|
16.8
|
1.0
|
|
HA
|
F:ALA52
|
2.7
|
14.2
|
1.0
|
|
H17
|
F:U52401
|
2.7
|
16.8
|
1.0
|
|
HB3
|
F:MET51
|
2.7
|
15.1
|
1.0
|
|
H8
|
F:U52401
|
2.8
|
16.8
|
1.0
|
|
HG
|
E:LEU25
|
2.8
|
14.5
|
1.0
|
|
O
|
F:MET51
|
3.0
|
15.1
|
1.0
|
|
C
|
F:MET51
|
3.0
|
15.1
|
1.0
|
|
CD1
|
E:LEU25
|
3.1
|
14.5
|
1.0
|
|
N19
|
F:U52401
|
3.1
|
16.8
|
1.0
|
|
HD12
|
E:LEU25
|
3.1
|
14.5
|
1.0
|
|
CG
|
E:LEU25
|
3.1
|
14.5
|
1.0
|
|
N
|
F:ALA52
|
3.2
|
14.2
|
1.0
|
|
CD2
|
E:LEU25
|
3.2
|
14.5
|
1.0
|
|
HD1
|
F:TYR58
|
3.3
|
15.6
|
1.0
|
|
HB2
|
F:MET51
|
3.3
|
15.1
|
1.0
|
|
CB
|
F:MET51
|
3.4
|
15.1
|
1.0
|
|
HB3
|
E:ASN21
|
3.4
|
14.0
|
1.0
|
|
CA
|
F:ALA52
|
3.4
|
14.2
|
1.0
|
|
HD23
|
E:LEU25
|
3.6
|
14.5
|
1.0
|
|
H
|
F:ALA52
|
3.7
|
14.2
|
1.0
|
|
CA
|
F:MET51
|
3.8
|
15.1
|
1.0
|
|
N25
|
F:U52401
|
3.9
|
16.8
|
1.0
|
|
N23
|
F:U52401
|
3.9
|
16.8
|
1.0
|
|
HD13
|
E:LEU25
|
4.0
|
14.5
|
1.0
|
|
HD22
|
E:LEU25
|
4.0
|
14.5
|
1.0
|
|
CD1
|
F:TYR58
|
4.0
|
15.6
|
1.0
|
|
HB2
|
F:ALA52
|
4.1
|
14.2
|
1.0
|
|
O
|
E:ASN21
|
4.1
|
14.0
|
1.0
|
|
HE2
|
F:MET51
|
4.2
|
15.1
|
1.0
|
|
HB2
|
F:TYR58
|
4.3
|
15.6
|
1.0
|
|
HA
|
F:MET51
|
4.3
|
15.1
|
1.0
|
|
CB
|
F:ALA52
|
4.3
|
14.2
|
1.0
|
|
CB
|
E:ASN21
|
4.3
|
14.0
|
1.0
|
|
HE1
|
F:TYR58
|
4.4
|
15.6
|
1.0
|
|
C24
|
F:U52401
|
4.4
|
16.8
|
1.0
|
|
C18
|
F:U52401
|
4.5
|
16.8
|
1.0
|
|
C
|
F:ALA52
|
4.5
|
14.2
|
1.0
|
|
CE1
|
F:TYR58
|
4.6
|
15.6
|
1.0
|
|
C
|
E:ASN21
|
4.6
|
14.0
|
1.0
|
|
CB
|
E:LEU25
|
4.6
|
14.5
|
1.0
|
|
CG
|
F:MET51
|
4.7
|
15.1
|
1.0
|
|
O
|
F:THR48
|
4.8
|
15.1
|
1.0
|
|
HB1
|
F:ALA52
|
4.8
|
14.2
|
1.0
|
|
HB2
|
E:ASN21
|
4.8
|
14.0
|
1.0
|
|
O
|
F:ALA52
|
4.9
|
14.2
|
1.0
|
|
CG
|
F:TYR58
|
4.9
|
15.6
|
1.0
|
|
HB2
|
E:LEU25
|
4.9
|
14.5
|
1.0
|
|
H7
|
F:U52401
|
4.9
|
16.8
|
1.0
|
|
N
|
F:MET51
|
5.0
|
15.1
|
1.0
|
|
HG2
|
F:MET51
|
5.0
|
15.1
|
1.0
|
|
HA
|
E:LEU22
|
5.0
|
13.9
|
1.0
|
|
CA
|
E:ASN21
|
5.0
|
14.0
|
1.0
|
|
Chlorine binding site 7 out
of 8 in 6xmx
Go back to
Chlorine Binding Sites List in 6xmx
Chlorine binding site 7 out
of 8 in the Cryo-Em Structure of BCL6 Bound to Bi-3802
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 7 of Cryo-Em Structure of BCL6 Bound to Bi-3802 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Cl401
b:25.9
occ:1.00
|
CL1
|
G:U52401
|
0.0
|
25.9
|
1.0
|
|
C27
|
G:U52401
|
1.7
|
25.9
|
1.0
|
|
C26
|
G:U52401
|
2.6
|
25.9
|
1.0
|
|
H17
|
G:U52401
|
2.7
|
25.9
|
1.0
|
|
C22
|
G:U52401
|
2.7
|
25.9
|
1.0
|
|
HB3
|
G:MET51
|
2.7
|
24.9
|
1.0
|
|
HA
|
G:ALA52
|
2.7
|
25.1
|
1.0
|
|
HD11
|
H:LEU25
|
2.7
|
25.4
|
1.0
|
|
H8
|
G:U52401
|
2.8
|
25.9
|
1.0
|
|
HB3
|
H:ASN21
|
2.8
|
25.7
|
1.0
|
|
O
|
G:MET51
|
3.0
|
24.9
|
1.0
|
|
C
|
G:MET51
|
3.0
|
24.9
|
1.0
|
|
N19
|
G:U52401
|
3.1
|
25.9
|
1.0
|
|
N
|
G:ALA52
|
3.2
|
25.1
|
1.0
|
|
HG
|
H:LEU25
|
3.2
|
25.4
|
1.0
|
|
HD21
|
H:LEU25
|
3.2
|
25.4
|
1.0
|
|
HD1
|
G:TYR58
|
3.3
|
25.0
|
1.0
|
|
HB2
|
G:MET51
|
3.4
|
24.9
|
1.0
|
|
CB
|
G:MET51
|
3.4
|
24.9
|
1.0
|
|
CA
|
G:ALA52
|
3.4
|
25.1
|
1.0
|
|
CD1
|
H:LEU25
|
3.5
|
25.4
|
1.0
|
|
CG
|
H:LEU25
|
3.7
|
25.4
|
1.0
|
|
H
|
G:ALA52
|
3.7
|
25.1
|
1.0
|
|
HD12
|
H:LEU25
|
3.7
|
25.4
|
1.0
|
|
CB
|
H:ASN21
|
3.8
|
25.7
|
1.0
|
|
CA
|
G:MET51
|
3.8
|
24.9
|
1.0
|
|
N25
|
G:U52401
|
3.9
|
25.9
|
1.0
|
|
CD2
|
H:LEU25
|
3.9
|
25.4
|
1.0
|
|
N23
|
G:U52401
|
3.9
|
25.9
|
1.0
|
|
CD1
|
G:TYR58
|
4.0
|
25.0
|
1.0
|
|
O
|
H:ASN21
|
4.0
|
25.7
|
1.0
|
|
HB2
|
G:ALA52
|
4.1
|
25.1
|
1.0
|
|
HB2
|
H:ASN21
|
4.1
|
25.7
|
1.0
|
|
HE2
|
G:MET51
|
4.2
|
24.9
|
1.0
|
|
HB2
|
G:TYR58
|
4.3
|
25.0
|
1.0
|
|
HA
|
G:MET51
|
4.3
|
24.9
|
1.0
|
|
HD13
|
H:LEU25
|
4.3
|
25.4
|
1.0
|
|
CB
|
G:ALA52
|
4.3
|
25.1
|
1.0
|
|
C
|
H:ASN21
|
4.3
|
25.7
|
1.0
|
|
C24
|
G:U52401
|
4.4
|
25.9
|
1.0
|
|
HE1
|
G:TYR58
|
4.4
|
25.0
|
1.0
|
|
CG
|
H:ASN21
|
4.4
|
25.7
|
1.0
|
|
C18
|
G:U52401
|
4.5
|
25.9
|
1.0
|
|
C
|
G:ALA52
|
4.5
|
25.1
|
1.0
|
|
HD23
|
H:LEU25
|
4.5
|
25.4
|
1.0
|
|
HD22
|
H:LEU25
|
4.5
|
25.4
|
1.0
|
|
CA
|
H:ASN21
|
4.6
|
25.7
|
1.0
|
|
CE1
|
G:TYR58
|
4.6
|
25.0
|
1.0
|
|
CG
|
G:MET51
|
4.7
|
24.9
|
1.0
|
|
HB1
|
G:ALA52
|
4.7
|
25.1
|
1.0
|
|
O
|
G:THR48
|
4.8
|
24.6
|
1.0
|
|
HA
|
H:ASN21
|
4.8
|
25.7
|
1.0
|
|
O
|
G:ALA52
|
4.9
|
25.1
|
1.0
|
|
CG
|
G:TYR58
|
4.9
|
25.0
|
1.0
|
|
OD1
|
H:ASN21
|
4.9
|
25.7
|
1.0
|
|
HA
|
H:LEU22
|
4.9
|
25.2
|
1.0
|
|
H7
|
G:U52401
|
4.9
|
25.9
|
1.0
|
|
N
|
G:MET51
|
5.0
|
24.9
|
1.0
|
|
HD22
|
H:ASN21
|
5.0
|
25.7
|
1.0
|
|
Chlorine binding site 8 out
of 8 in 6xmx
Go back to
Chlorine Binding Sites List in 6xmx
Chlorine binding site 8 out
of 8 in the Cryo-Em Structure of BCL6 Bound to Bi-3802
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 8 of Cryo-Em Structure of BCL6 Bound to Bi-3802 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Cl401
b:24.5
occ:1.00
|
CL1
|
H:U52401
|
0.0
|
24.5
|
1.0
|
|
C27
|
H:U52401
|
1.7
|
24.5
|
1.0
|
|
HD11
|
G:LEU25
|
2.6
|
22.9
|
1.0
|
|
C26
|
H:U52401
|
2.6
|
24.5
|
1.0
|
|
H17
|
H:U52401
|
2.7
|
24.5
|
1.0
|
|
C22
|
H:U52401
|
2.7
|
24.5
|
1.0
|
|
HA
|
H:ALA52
|
2.7
|
23.5
|
1.0
|
|
HB3
|
H:MET51
|
2.7
|
24.5
|
1.0
|
|
H8
|
H:U52401
|
2.8
|
24.5
|
1.0
|
|
HD21
|
G:LEU25
|
2.8
|
22.9
|
1.0
|
|
HG
|
G:LEU25
|
2.8
|
22.9
|
1.0
|
|
O
|
H:MET51
|
3.0
|
24.5
|
1.0
|
|
HB3
|
G:ASN21
|
3.0
|
23.1
|
1.0
|
|
C
|
H:MET51
|
3.0
|
24.5
|
1.0
|
|
N19
|
H:U52401
|
3.1
|
24.5
|
1.0
|
|
CD1
|
G:LEU25
|
3.1
|
22.9
|
1.0
|
|
HD12
|
G:LEU25
|
3.1
|
22.9
|
1.0
|
|
N
|
H:ALA52
|
3.2
|
23.5
|
1.0
|
|
CG
|
G:LEU25
|
3.2
|
22.9
|
1.0
|
|
HB2
|
H:MET51
|
3.3
|
24.5
|
1.0
|
|
HD1
|
H:TYR58
|
3.3
|
25.4
|
1.0
|
|
CB
|
H:MET51
|
3.3
|
24.5
|
1.0
|
|
CA
|
H:ALA52
|
3.4
|
23.5
|
1.0
|
|
CD2
|
G:LEU25
|
3.4
|
22.9
|
1.0
|
|
H
|
H:ALA52
|
3.7
|
23.5
|
1.0
|
|
CA
|
H:MET51
|
3.8
|
24.5
|
1.0
|
|
O
|
G:ASN21
|
3.8
|
23.1
|
1.0
|
|
N25
|
H:U52401
|
3.9
|
24.5
|
1.0
|
|
N23
|
H:U52401
|
3.9
|
24.5
|
1.0
|
|
CB
|
G:ASN21
|
3.9
|
23.1
|
1.0
|
|
HD23
|
G:LEU25
|
4.0
|
22.9
|
1.0
|
|
CD1
|
H:TYR58
|
4.0
|
25.4
|
1.0
|
|
HD13
|
G:LEU25
|
4.0
|
22.9
|
1.0
|
|
HB2
|
H:ALA52
|
4.1
|
23.5
|
1.0
|
|
HD22
|
G:LEU25
|
4.1
|
22.9
|
1.0
|
|
HE2
|
H:MET51
|
4.2
|
24.5
|
1.0
|
|
HB2
|
H:TYR58
|
4.3
|
25.4
|
1.0
|
|
HA
|
H:MET51
|
4.3
|
24.5
|
1.0
|
|
C
|
G:ASN21
|
4.3
|
23.1
|
1.0
|
|
CB
|
H:ALA52
|
4.3
|
23.5
|
1.0
|
|
HE1
|
H:TYR58
|
4.4
|
25.4
|
1.0
|
|
C24
|
H:U52401
|
4.4
|
24.5
|
1.0
|
|
HB2
|
G:ASN21
|
4.4
|
23.1
|
1.0
|
|
C
|
H:ALA52
|
4.5
|
23.5
|
1.0
|
|
C18
|
H:U52401
|
4.5
|
24.5
|
1.0
|
|
CE1
|
H:TYR58
|
4.6
|
25.4
|
1.0
|
|
CA
|
G:ASN21
|
4.6
|
23.1
|
1.0
|
|
CG
|
H:MET51
|
4.7
|
24.5
|
1.0
|
|
CB
|
G:LEU25
|
4.7
|
22.9
|
1.0
|
|
CG
|
G:ASN21
|
4.7
|
23.1
|
1.0
|
|
HA
|
G:LEU22
|
4.7
|
23.2
|
1.0
|
|
O
|
H:THR48
|
4.8
|
24.2
|
1.0
|
|
HA
|
G:ASN21
|
4.8
|
23.1
|
1.0
|
|
HB1
|
H:ALA52
|
4.8
|
23.5
|
1.0
|
|
O
|
H:ALA52
|
4.9
|
23.5
|
1.0
|
|
CG
|
H:TYR58
|
4.9
|
25.4
|
1.0
|
|
HB2
|
G:LEU25
|
4.9
|
22.9
|
1.0
|
|
N
|
H:MET51
|
4.9
|
24.5
|
1.0
|
|
H7
|
H:U52401
|
4.9
|
24.5
|
1.0
|
|
HG2
|
H:MET51
|
5.0
|
24.5
|
1.0
|
|
CB
|
H:TYR58
|
5.0
|
25.4
|
1.0
|
|
Reference:
M.Slabicki,
H.Yoon,
J.Koeppel,
L.Nitsch,
S.S.Roy Burman,
C.Di Genua,
K.A.Donovan,
A.S.Sperling,
M.Hunkeler,
J.M.Tsai,
R.Sharma,
A.Guirguis,
C.Zou,
P.Chudasama,
J.A.Gasser,
P.G.Miller,
C.Scholl,
S.Frohling,
R.P.Nowak,
E.S.Fischer,
B.L.Ebert.
Small-Molecule-Induced Polymerization Triggers Degradation of BCL6. Nature 2020.
ISSN: ESSN 1476-4687
PubMed: 33208943
DOI: 10.1038/S41586-020-2925-1
Page generated: Mon Jul 29 17:17:21 2024
|
