Chlorine in PDB 6xwg: Crystal Structure of the Human Rxr/Rar Dna-Binding Domain Heterodimer Bound to the Human RARB2 DR5 Response Element

The structure of Crystal Structure of the Human Rxr/Rar Dna-Binding Domain Heterodimer Bound to the Human RARB2 DR5 Response Element, PDB code: 6xwg was solved by A.G.Mcewen, P.Poussin-Courmontagne, C.Peluso-Iltis, N.Rochel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.51 / 2.40
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	56.714, 56.714, 238.364, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 20.7

The structure of Crystal Structure of the Human Rxr/Rar Dna-Binding Domain Heterodimer Bound to the Human RARB2 DR5 Response Element also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Chlorine atom in the Crystal Structure of the Human Rxr/Rar Dna-Binding Domain Heterodimer Bound to the Human RARB2 DR5 Response Element (pdb code 6xwg). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Human Rxr/Rar Dna-Binding Domain Heterodimer Bound to the Human RARB2 DR5 Response Element, PDB code: 6xwg:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Human Rxr/Rar Dna-Binding Domain Heterodimer Bound to the Human RARB2 DR5 Response Element


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Human Rxr/Rar Dna-Binding Domain Heterodimer Bound to the Human RARB2 DR5 Response Element within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl304 b:77.6 occ:1.00 OE2 C:GLU203 2.7 0.7 1.0 N C:ARG202 3.4 72.9 1.0 CD C:GLU203 3.6 0.2 1.0 CG C:GLU203 3.8 0.1 1.0 NE C:ARG202 3.9 0.3 1.0 N C:GLU203 3.9 81.8 1.0 CB C:ARG202 4.0 73.1 1.0 NH2 C:ARG202 4.0 0.5 1.0 CA C:ARG202 4.1 73.5 1.0 CZ C:ARG202 4.2 0.3 1.0 C C:LYS201 4.2 75.0 1.0 CA C:LYS201 4.2 70.4 1.0 C C:ARG202 4.5 82.2 1.0 CB C:LYS201 4.5 76.2 1.0 CB C:GLU203 4.5 90.0 1.0 CG C:ARG202 4.6 78.5 1.0 OE1 C:GLU203 4.7 0.3 1.0 CD C:ARG202 4.8 95.8 1.0 CA C:GLU203 4.8 85.4 1.0 CG C:LYS201 5.0 85.5 1.0

J.Osz, A.G.Mcewen, M.Bourguet, F.Przybilla, C.Peluso-Iltis, P.Poussin-Courmontagne, Y.Mely, S.Cianferani, C.M.Jeffries, D.I.Svergun, N.Rochel. Structural Basis For Dna Recognition and Allosteric Control of the Retinoic Acid Receptors Rar-Rxr. Nucleic Acids Res. V. 48 9969 2020.
ISSN: ESSN 1362-4962
PubMed: 32974652
DOI: 10.1093/NAR/GKAA697