Chlorine in PDB 6zcr: Syk Kinase Domain in Complex with Azabenzimidazole Inhibitor 7

All present enzymatic activity of Syk Kinase Domain in Complex with Azabenzimidazole Inhibitor 7:
2.7.10.2;

The structure of Syk Kinase Domain in Complex with Azabenzimidazole Inhibitor 7, PDB code: 6zcr was solved by J.A.Read, J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	60.26 / 1.73
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	39.46, 82.791, 87.876, 90, 90, 90
R / Rfree (%)	18.8 / 21.8

The structure of Syk Kinase Domain in Complex with Azabenzimidazole Inhibitor 7 also contains other interesting chemical elements:

Fluorine

(F)

1 atom

The binding sites of Chlorine atom in the Syk Kinase Domain in Complex with Azabenzimidazole Inhibitor 7 (pdb code 6zcr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Syk Kinase Domain in Complex with Azabenzimidazole Inhibitor 7, PDB code: 6zcr:

Chlorine binding site 1 out of 1 in the Syk Kinase Domain in Complex with Azabenzimidazole Inhibitor 7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Syk Kinase Domain in Complex with Azabenzimidazole Inhibitor 7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl701 b:26.0 occ:1.00 CL A:5JG701 0.0 26.0 1.0 C18 A:5JG701 1.7 24.3 1.0 C19 A:5JG701 2.7 24.6 1.0 C17 A:5JG701 2.7 24.7 1.0 N21 A:5JG701 3.0 22.3 1.0 O A:HOH883 3.4 34.2 1.0 SD A:MET448 3.6 37.5 1.0 O A:HOH869 3.6 34.6 1.0 CB A:ALA400 3.7 22.8 1.0 CE A:MET448 3.7 34.9 1.0 CB A:MET448 3.9 25.2 1.0 N20 A:5JG701 4.0 25.3 1.0 C15 A:5JG701 4.0 23.2 1.0 CG1 A:VAL433 4.2 27.0 1.0 CD1 A:LEU501 4.3 26.3 1.0 C14 A:5JG701 4.4 24.1 1.0 C22 A:5JG701 4.4 22.9 1.0 CG A:MET448 4.5 30.9 1.0 O A:GLU449 4.7 23.3 1.0 C28 A:5JG701 4.8 25.5 1.0 O A:ALA400 5.0 22.0 1.0 CB A:SER511 5.0 21.8 1.0

J.A.Read, J.A.Read, J.Patel. N/A N/A.