Chlorine in PDB 6zef: Structure of PP1(7-300) Bound to PHACTR1 (516-580) at pH 5.25

Enzymatic activity of Structure of PP1(7-300) Bound to PHACTR1 (516-580) at pH 5.25

All present enzymatic activity of Structure of PP1(7-300) Bound to PHACTR1 (516-580) at pH 5.25:
3.1.3.16;

Protein crystallography data

The structure of Structure of PP1(7-300) Bound to PHACTR1 (516-580) at pH 5.25, PDB code: 6zef was solved by S.Mouilleron, R.Treisman, R.Fedoryshchak, R.Lee, A.M.Butler, M.Prechova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 56.05 / 1.94
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 47.510, 57.550, 89.614, 78.08, 74.67, 81.66
R / Rfree (%) 18.2 / 21.2

Other elements in 6zef:

The structure of Structure of PP1(7-300) Bound to PHACTR1 (516-580) at pH 5.25 also contains other interesting chemical elements:

Manganese (Mn) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of PP1(7-300) Bound to PHACTR1 (516-580) at pH 5.25 (pdb code 6zef). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of PP1(7-300) Bound to PHACTR1 (516-580) at pH 5.25, PDB code: 6zef:

Chlorine binding site 1 out of 1 in 6zef

Go back to Chlorine Binding Sites List in 6zef
Chlorine binding site 1 out of 1 in the Structure of PP1(7-300) Bound to PHACTR1 (516-580) at pH 5.25


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of PP1(7-300) Bound to PHACTR1 (516-580) at pH 5.25 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl405

b:38.8
occ:1.00
HE A:ARG191 2.2 30.1 1.0
H A:ARG191 2.8 36.3 1.0
HH21 A:ARG191 2.8 30.3 1.0
NE A:ARG191 3.1 25.0 1.0
HA A:MET190 3.1 41.8 1.0
HB2 A:ARG191 3.2 32.6 1.0
N A:ARG191 3.4 30.1 1.0
NH2 A:ARG191 3.5 25.1 1.0
HG3 A:ARG191 3.5 31.8 1.0
O A:ILE189 3.6 34.6 1.0
HB A:ILE51 3.7 31.3 1.0
CZ A:ARG191 3.7 26.2 1.0
HD12 A:ILE51 3.8 34.2 1.0
CB A:ARG191 3.9 27.1 1.0
CA A:MET190 4.0 34.8 1.0
CG A:ARG191 4.0 26.4 1.0
C A:MET190 4.1 33.6 1.0
HG3 A:MET190 4.1 56.6 1.0
CD A:ARG191 4.1 25.8 1.0
CA A:ARG191 4.3 28.3 1.0
HH22 A:ARG191 4.3 30.3 1.0
HD22 A:LEU47 4.5 37.4 1.0
C A:ILE189 4.5 32.9 1.0
HD3 A:ARG191 4.6 31.1 1.0
CB A:ILE51 4.7 26.0 1.0
CD1 A:ILE51 4.7 28.4 1.0
HG2 A:MET190 4.7 56.6 1.0
N A:MET190 4.7 34.2 1.0
CG A:MET190 4.8 47.1 1.0
HD2 A:ARG191 4.8 31.1 1.0
HB3 A:ARG191 4.8 32.6 1.0
O A:ARG191 4.8 32.4 1.0
HG21 A:ILE51 4.8 32.7 1.0
HD23 A:LEU47 4.9 37.4 1.0
HG2 A:ARG191 5.0 31.8 1.0
CB A:MET190 5.0 40.6 1.0
C A:ARG191 5.0 31.9 1.0

Reference:

R.O.Fedoryshchak, M.Prechova, A.Butler, R.Lee, N.O'reilly, H.R.Flynn, A.P.Snijders, N.Eder, S.Ultanir, S.Mouilleron, R.Treisman. Molecular Basis For Substrate Specificity of the PHACTR1/PP1 Phosphatase Holoenzyme. Elife V. 9 2020.
ISSN: ESSN 2050-084X
PubMed: 32975518
DOI: 10.7554/ELIFE.61509
Page generated: Sat Dec 12 14:46:43 2020

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