Chlorine in PDB 6zek: Crystal Structure of Mouse Csad
Enzymatic activity of Crystal Structure of Mouse Csad
All present enzymatic activity of Crystal Structure of Mouse Csad:
4.1.1.11;
4.1.1.29;
Protein crystallography data
The structure of Crystal Structure of Mouse Csad, PDB code: 6zek
was solved by
E.Mahootchi,
A.Raasakka,
J.Haavik,
P.Kursula,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
46.89 /
2.10
|
|
Space group
|
P 1 21 1
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
72.94,
113.26,
113.37,
90,
95.81,
90
|
|
R / Rfree (%)
|
17.9 /
23.5
|
Other elements in 6zek:
The structure of Crystal Structure of Mouse Csad also contains other interesting chemical elements:
Chlorine Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
13;
Binding sites:
The binding sites of Chlorine atom in the Crystal Structure of Mouse Csad
(pdb code 6zek). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 13 binding sites of Chlorine where determined in the
Crystal Structure of Mouse Csad, PDB code: 6zek:
Jump to Chlorine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Chlorine binding site 1 out
of 13 in 6zek
Go back to
Chlorine Binding Sites List in 6zek
Chlorine binding site 1 out
of 13 in the Crystal Structure of Mouse Csad
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of Mouse Csad within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Cl503
b:19.9
occ:1.00
|
H
|
A:ARG359
|
2.5
|
35.8
|
1.0
|
|
HE22
|
C:GLN312
|
2.6
|
38.8
|
1.0
|
|
HE22
|
A:GLN355
|
2.6
|
43.0
|
1.0
|
|
HB2
|
A:ARG359
|
3.1
|
37.0
|
1.0
|
|
HB3
|
A:PRO150
|
3.2
|
28.1
|
1.0
|
|
HG3
|
C:GLN312
|
3.2
|
46.5
|
1.0
|
|
HG3
|
A:ARG358
|
3.2
|
42.4
|
1.0
|
|
HA
|
A:ARG358
|
3.3
|
35.3
|
1.0
|
|
N
|
A:ARG359
|
3.4
|
29.8
|
1.0
|
|
NE2
|
A:GLN355
|
3.4
|
35.8
|
1.0
|
|
NE2
|
C:GLN312
|
3.4
|
32.3
|
1.0
|
|
HG3
|
A:ARG359
|
3.4
|
49.5
|
1.0
|
|
HD3
|
A:ARG359
|
3.5
|
52.2
|
1.0
|
|
HB2
|
C:PRO150
|
3.8
|
35.3
|
1.0
|
|
CB
|
A:ARG359
|
3.8
|
30.8
|
1.0
|
|
HE21
|
A:GLN355
|
3.9
|
43.0
|
1.0
|
|
CG
|
C:GLN312
|
3.9
|
38.7
|
1.0
|
|
HE21
|
C:GLN312
|
4.0
|
38.8
|
1.0
|
|
CG
|
A:ARG359
|
4.0
|
41.3
|
1.0
|
|
HG2
|
C:GLN312
|
4.0
|
46.5
|
1.0
|
|
CB
|
A:PRO150
|
4.1
|
23.4
|
1.0
|
|
CG
|
A:ARG358
|
4.1
|
35.3
|
1.0
|
|
CA
|
A:ARG358
|
4.1
|
29.4
|
1.0
|
|
CD
|
C:GLN312
|
4.2
|
41.2
|
1.0
|
|
CA
|
A:ARG359
|
4.2
|
32.6
|
1.0
|
|
OE1
|
A:GLN355
|
4.2
|
32.2
|
1.0
|
|
CD
|
A:ARG359
|
4.2
|
43.5
|
1.0
|
|
CD
|
A:GLN355
|
4.2
|
38.1
|
1.0
|
|
C
|
A:ARG358
|
4.3
|
27.9
|
1.0
|
|
HG3
|
A:PRO150
|
4.3
|
40.1
|
1.0
|
|
HG2
|
A:ARG358
|
4.4
|
42.4
|
1.0
|
|
O
|
A:HOH724
|
4.6
|
38.0
|
1.0
|
|
CB
|
C:PRO150
|
4.6
|
29.4
|
1.0
|
|
HB2
|
A:PRO150
|
4.6
|
28.1
|
1.0
|
|
HD3
|
A:PRO150
|
4.6
|
37.8
|
1.0
|
|
HB3
|
C:PRO150
|
4.6
|
35.3
|
1.0
|
|
HA
|
A:PRO150
|
4.7
|
29.5
|
1.0
|
|
HB3
|
A:ARG359
|
4.7
|
37.0
|
1.0
|
|
CG
|
A:PRO150
|
4.7
|
33.5
|
1.0
|
|
CB
|
A:ARG358
|
4.7
|
32.0
|
1.0
|
|
HD2
|
A:ARG359
|
4.8
|
52.2
|
1.0
|
|
O
|
C:PRO150
|
4.8
|
31.1
|
1.0
|
|
HG2
|
A:ARG359
|
4.9
|
49.5
|
1.0
|
|
HA
|
A:ARG359
|
4.9
|
39.1
|
1.0
|
|
CA
|
A:PRO150
|
4.9
|
24.6
|
1.0
|
|
O
|
A:GLY357
|
4.9
|
36.2
|
1.0
|
|
HA
|
C:PRO150
|
5.0
|
37.0
|
1.0
|
|
Chlorine binding site 2 out
of 13 in 6zek
Go back to
Chlorine Binding Sites List in 6zek
Chlorine binding site 2 out
of 13 in the Crystal Structure of Mouse Csad
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Crystal Structure of Mouse Csad within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Cl504
b:33.9
occ:1.00
|
HZ3
|
A:LYS134
|
2.6
|
55.8
|
1.0
|
|
HA3
|
A:GLY374
|
2.7
|
36.1
|
1.0
|
|
HE1
|
A:TRP369
|
2.8
|
33.1
|
1.0
|
|
HE2
|
A:LYS134
|
2.9
|
46.1
|
1.0
|
|
HE3
|
A:LYS134
|
3.2
|
46.1
|
1.0
|
|
HZ2
|
A:TRP369
|
3.3
|
40.1
|
1.0
|
|
CE
|
A:LYS134
|
3.3
|
38.4
|
1.0
|
|
NZ
|
A:LYS134
|
3.3
|
46.5
|
1.0
|
|
H
|
A:GLY374
|
3.5
|
31.3
|
1.0
|
|
HA
|
C:SER62
|
3.5
|
36.2
|
1.0
|
|
CA
|
A:GLY374
|
3.6
|
30.1
|
1.0
|
|
NE1
|
A:TRP369
|
3.6
|
27.6
|
1.0
|
|
C
|
C:GLN61
|
3.7
|
33.5
|
1.0
|
|
HZ2
|
A:LYS134
|
3.7
|
55.8
|
1.0
|
|
O
|
C:GLN61
|
3.7
|
25.1
|
1.0
|
|
HA2
|
A:GLY374
|
3.8
|
36.1
|
1.0
|
|
HZ1
|
A:LYS134
|
3.9
|
55.8
|
1.0
|
|
N
|
A:GLY374
|
3.9
|
26.1
|
1.0
|
|
N
|
C:SER62
|
4.0
|
40.2
|
1.0
|
|
CZ2
|
A:TRP369
|
4.0
|
33.4
|
1.0
|
|
HA
|
C:GLN61
|
4.0
|
42.2
|
1.0
|
|
CE2
|
A:TRP369
|
4.2
|
35.2
|
1.0
|
|
CA
|
C:SER62
|
4.2
|
30.2
|
1.0
|
|
CA
|
C:GLN61
|
4.3
|
35.2
|
1.0
|
|
H
|
C:SER62
|
4.3
|
48.3
|
1.0
|
|
N
|
C:GLN61
|
4.4
|
34.0
|
1.0
|
|
OG
|
C:SER62
|
4.5
|
51.5
|
1.0
|
|
H
|
C:GLN61
|
4.7
|
40.7
|
1.0
|
|
O
|
C:LEU60
|
4.7
|
31.0
|
1.0
|
|
C
|
A:GLY374
|
4.7
|
28.8
|
1.0
|
|
C
|
C:LEU60
|
4.7
|
29.9
|
1.0
|
|
HB3
|
C:LEU60
|
4.8
|
36.5
|
1.0
|
|
CD
|
A:LYS134
|
4.8
|
38.0
|
1.0
|
|
CD1
|
A:TRP369
|
4.8
|
33.7
|
1.0
|
|
O
|
A:HOH756
|
4.9
|
39.8
|
1.0
|
|
HD11
|
A:LEU138
|
5.0
|
44.6
|
1.0
|
|
CB
|
C:SER62
|
5.0
|
38.2
|
1.0
|
|
Chlorine binding site 3 out
of 13 in 6zek
Go back to
Chlorine Binding Sites List in 6zek
Chlorine binding site 3 out
of 13 in the Crystal Structure of Mouse Csad
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of Crystal Structure of Mouse Csad within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Cl505
b:22.2
occ:1.00
|
HE21
|
A:GLN92
|
2.4
|
27.9
|
1.0
|
|
H
|
A:LEU93
|
2.5
|
28.6
|
1.0
|
|
HB3
|
A:GLN92
|
2.8
|
32.5
|
1.0
|
|
HB2
|
A:LEU93
|
3.0
|
33.9
|
1.0
|
|
O
|
C:HOH776
|
3.2
|
35.6
|
1.0
|
|
NE2
|
A:GLN92
|
3.2
|
23.2
|
1.0
|
|
N
|
A:LEU93
|
3.3
|
23.8
|
1.0
|
|
HD2
|
A:PHE94
|
3.4
|
41.4
|
1.0
|
|
HE3
|
A:LLP305
|
3.4
|
41.8
|
1.0
|
|
HE22
|
A:GLN92
|
3.5
|
27.9
|
1.0
|
|
O
|
A:HOH791
|
3.5
|
42.9
|
1.0
|
|
HG
|
A:LEU93
|
3.6
|
38.6
|
1.0
|
|
CB
|
A:GLN92
|
3.7
|
27.1
|
1.0
|
|
CB
|
A:LEU93
|
3.8
|
28.2
|
1.0
|
|
HE2
|
A:PHE94
|
4.0
|
46.0
|
1.0
|
|
O
|
A:HOH753
|
4.0
|
27.7
|
1.0
|
|
CA
|
A:LEU93
|
4.0
|
26.4
|
1.0
|
|
HA
|
A:GLN92
|
4.0
|
35.1
|
1.0
|
|
CD2
|
A:PHE94
|
4.1
|
34.5
|
1.0
|
|
CG
|
A:LEU93
|
4.2
|
32.2
|
1.0
|
|
O
|
A:HOH650
|
4.2
|
33.0
|
1.0
|
|
HB2
|
A:GLN92
|
4.2
|
32.5
|
1.0
|
|
CA
|
A:GLN92
|
4.3
|
29.2
|
1.0
|
|
CD
|
A:GLN92
|
4.3
|
32.4
|
1.0
|
|
C
|
A:GLN92
|
4.3
|
32.9
|
1.0
|
|
CE
|
A:LLP305
|
4.3
|
34.8
|
1.0
|
|
HD12
|
A:LEU93
|
4.4
|
27.0
|
1.0
|
|
H
|
A:PHE94
|
4.4
|
39.5
|
1.0
|
|
CE2
|
A:PHE94
|
4.4
|
38.3
|
1.0
|
|
CG
|
A:GLN92
|
4.4
|
30.0
|
1.0
|
|
C
|
A:LEU93
|
4.5
|
31.6
|
1.0
|
|
HG3
|
A:GLN92
|
4.5
|
36.0
|
1.0
|
|
HG3
|
A:LLP305
|
4.6
|
32.3
|
1.0
|
|
HB3
|
A:LEU93
|
4.6
|
33.9
|
1.0
|
|
N
|
A:PHE94
|
4.7
|
32.9
|
1.0
|
|
HE2
|
A:LLP305
|
4.7
|
41.8
|
1.0
|
|
NZ
|
A:LLP305
|
4.8
|
31.3
|
1.0
|
|
CD1
|
A:LEU93
|
4.8
|
22.5
|
1.0
|
|
HA
|
A:LEU93
|
4.9
|
31.6
|
1.0
|
|
C4'
|
A:LLP305
|
5.0
|
33.7
|
1.0
|
|
Chlorine binding site 4 out
of 13 in 6zek
Go back to
Chlorine Binding Sites List in 6zek
Chlorine binding site 4 out
of 13 in the Crystal Structure of Mouse Csad
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 4 of Crystal Structure of Mouse Csad within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Cl503
b:67.6
occ:1.00
|
HB2
|
B:ARG389
|
3.2
|
33.7
|
1.0
|
|
O
|
B:ALA386
|
3.3
|
41.9
|
1.0
|
|
O
|
B:HOH723
|
3.5
|
42.4
|
1.0
|
|
HB1
|
B:ALA386
|
3.6
|
35.5
|
1.0
|
|
HB3
|
B:ARG389
|
3.9
|
33.7
|
1.0
|
|
HB2
|
B:TYR390
|
3.9
|
34.1
|
1.0
|
|
CB
|
B:ARG389
|
4.0
|
28.1
|
1.0
|
|
H
|
B:TYR390
|
4.0
|
32.3
|
1.0
|
|
HA
|
B:ALA386
|
4.1
|
38.1
|
1.0
|
|
C
|
B:ALA386
|
4.2
|
32.6
|
1.0
|
|
N
|
B:TYR390
|
4.4
|
26.9
|
1.0
|
|
OE2
|
B:GLU393
|
4.4
|
42.0
|
1.0
|
|
CB
|
B:ALA386
|
4.4
|
29.6
|
1.0
|
|
CA
|
B:ALA386
|
4.5
|
31.7
|
1.0
|
|
HG3
|
B:ARG389
|
4.6
|
37.3
|
1.0
|
|
HA
|
B:TYR390
|
4.7
|
37.0
|
1.0
|
|
CB
|
B:TYR390
|
4.8
|
28.4
|
1.0
|
|
CG
|
B:ARG389
|
4.8
|
31.1
|
1.0
|
|
C
|
B:ARG389
|
4.9
|
34.1
|
1.0
|
|
HB2
|
B:ALA386
|
4.9
|
35.5
|
1.0
|
|
CA
|
B:TYR390
|
4.9
|
30.9
|
1.0
|
|
HE21
|
B:GLN476
|
4.9
|
51.1
|
1.0
|
|
CA
|
B:ARG389
|
5.0
|
29.4
|
1.0
|
|
Chlorine binding site 5 out
of 13 in 6zek
Go back to
Chlorine Binding Sites List in 6zek
Chlorine binding site 5 out
of 13 in the Crystal Structure of Mouse Csad
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 5 of Crystal Structure of Mouse Csad within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Cl504
b:25.5
occ:1.00
|
HE22
|
B:GLN355
|
2.5
|
41.6
|
1.0
|
|
H
|
B:ARG359
|
2.6
|
43.5
|
1.0
|
|
OE1
|
D:GLN312
|
2.9
|
52.3
|
1.0
|
|
HB3
|
B:PRO150
|
3.1
|
35.7
|
1.0
|
|
HG3
|
B:ARG359
|
3.1
|
50.3
|
1.0
|
|
HE21
|
D:GLN312
|
3.2
|
45.0
|
1.0
|
|
HB2
|
B:ARG359
|
3.2
|
45.4
|
1.0
|
|
NE2
|
B:GLN355
|
3.3
|
34.7
|
1.0
|
|
CD
|
D:GLN312
|
3.4
|
44.1
|
1.0
|
|
HA
|
B:ARG358
|
3.4
|
30.0
|
1.0
|
|
HG3
|
B:ARG358
|
3.5
|
51.1
|
1.0
|
|
N
|
B:ARG359
|
3.5
|
36.3
|
1.0
|
|
HD3
|
B:ARG359
|
3.5
|
55.4
|
1.0
|
|
NE2
|
D:GLN312
|
3.5
|
37.5
|
1.0
|
|
HE21
|
B:GLN355
|
3.6
|
41.6
|
1.0
|
|
HB2
|
D:PRO150
|
3.7
|
34.0
|
1.0
|
|
CG
|
B:ARG359
|
3.8
|
41.9
|
1.0
|
|
CB
|
B:ARG359
|
3.8
|
37.9
|
1.0
|
|
CB
|
B:PRO150
|
4.1
|
29.8
|
1.0
|
|
CD
|
B:ARG359
|
4.1
|
46.2
|
1.0
|
|
HE22
|
D:GLN312
|
4.2
|
45.0
|
1.0
|
|
CD
|
B:GLN355
|
4.3
|
39.5
|
1.0
|
|
HG3
|
B:PRO150
|
4.3
|
30.9
|
1.0
|
|
CA
|
B:ARG359
|
4.3
|
34.6
|
1.0
|
|
CA
|
B:ARG358
|
4.3
|
25.0
|
1.0
|
|
C
|
B:ARG358
|
4.4
|
32.4
|
1.0
|
|
CG
|
B:ARG358
|
4.4
|
42.6
|
1.0
|
|
OE1
|
B:GLN355
|
4.4
|
33.5
|
1.0
|
|
HB3
|
D:PRO150
|
4.4
|
34.0
|
1.0
|
|
CB
|
D:PRO150
|
4.5
|
28.3
|
1.0
|
|
HD2
|
B:ARG359
|
4.5
|
55.4
|
1.0
|
|
HB2
|
B:PRO150
|
4.6
|
35.7
|
1.0
|
|
HG3
|
D:GLN312
|
4.6
|
57.3
|
1.0
|
|
HD3
|
B:PRO150
|
4.6
|
29.8
|
1.0
|
|
CG
|
D:GLN312
|
4.6
|
47.8
|
1.0
|
|
HA
|
B:PRO150
|
4.6
|
39.5
|
1.0
|
|
CG
|
B:PRO150
|
4.7
|
25.7
|
1.0
|
|
HG2
|
B:ARG359
|
4.7
|
50.3
|
1.0
|
|
HG2
|
B:ARG358
|
4.7
|
51.1
|
1.0
|
|
HB3
|
B:ARG359
|
4.7
|
45.4
|
1.0
|
|
HB2
|
D:GLN312
|
4.7
|
52.8
|
1.0
|
|
O
|
D:PRO150
|
4.8
|
29.7
|
1.0
|
|
HA
|
D:PRO150
|
4.9
|
33.4
|
1.0
|
|
CA
|
B:PRO150
|
4.9
|
33.0
|
1.0
|
|
CB
|
B:ARG358
|
4.9
|
34.3
|
1.0
|
|
HA
|
B:ARG359
|
4.9
|
41.5
|
1.0
|
|
O
|
B:GLY357
|
4.9
|
40.6
|
1.0
|
|
Chlorine binding site 6 out
of 13 in 6zek
Go back to
Chlorine Binding Sites List in 6zek
Chlorine binding site 6 out
of 13 in the Crystal Structure of Mouse Csad
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 6 of Crystal Structure of Mouse Csad within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Cl505
b:42.3
occ:1.00
|
HA3
|
B:GLY374
|
2.7
|
38.6
|
1.0
|
|
HE1
|
B:TRP369
|
2.9
|
36.6
|
1.0
|
|
HE2
|
B:LYS134
|
3.0
|
50.4
|
1.0
|
|
HZ1
|
B:LYS134
|
3.0
|
55.1
|
1.0
|
|
H
|
B:GLY374
|
3.2
|
37.7
|
1.0
|
|
O
|
D:GLN61
|
3.4
|
26.5
|
1.0
|
|
CA
|
B:GLY374
|
3.4
|
32.2
|
1.0
|
|
HA
|
D:SER62
|
3.4
|
35.3
|
1.0
|
|
HA2
|
B:GLY374
|
3.5
|
38.6
|
1.0
|
|
CE
|
B:LYS134
|
3.6
|
42.0
|
1.0
|
|
C
|
D:GLN61
|
3.6
|
35.8
|
1.0
|
|
NZ
|
B:LYS134
|
3.6
|
45.9
|
1.0
|
|
HE3
|
B:LYS134
|
3.6
|
50.4
|
1.0
|
|
HZ2
|
B:TRP369
|
3.7
|
44.3
|
1.0
|
|
N
|
B:GLY374
|
3.7
|
31.4
|
1.0
|
|
NE1
|
B:TRP369
|
3.7
|
30.5
|
1.0
|
|
HZ3
|
B:LYS134
|
3.9
|
55.1
|
1.0
|
|
N
|
D:SER62
|
3.9
|
35.6
|
1.0
|
|
HA
|
D:GLN61
|
4.0
|
46.2
|
1.0
|
|
CA
|
D:SER62
|
4.1
|
29.4
|
1.0
|
|
CA
|
D:GLN61
|
4.2
|
38.5
|
1.0
|
|
CZ2
|
B:TRP369
|
4.3
|
36.9
|
1.0
|
|
HZ2
|
B:LYS134
|
4.3
|
55.1
|
1.0
|
|
N
|
D:GLN61
|
4.4
|
32.6
|
1.0
|
|
CE2
|
B:TRP369
|
4.4
|
30.3
|
1.0
|
|
H
|
D:SER62
|
4.4
|
42.7
|
1.0
|
|
OG
|
D:SER62
|
4.5
|
43.1
|
1.0
|
|
H
|
D:GLN61
|
4.6
|
39.1
|
1.0
|
|
HB3
|
D:LEU60
|
4.6
|
44.0
|
1.0
|
|
C
|
D:LEU60
|
4.7
|
35.5
|
1.0
|
|
O
|
D:LEU60
|
4.7
|
31.6
|
1.0
|
|
C
|
B:GLY374
|
4.7
|
34.2
|
1.0
|
|
CD1
|
B:TRP369
|
4.9
|
34.6
|
1.0
|
|
C
|
B:GLY373
|
4.9
|
28.6
|
1.0
|
|
HB2
|
D:LEU60
|
4.9
|
44.0
|
1.0
|
|
CB
|
D:SER62
|
5.0
|
33.5
|
1.0
|
|
CD
|
B:LYS134
|
5.0
|
37.4
|
1.0
|
|
Chlorine binding site 7 out
of 13 in 6zek
Go back to
Chlorine Binding Sites List in 6zek
Chlorine binding site 7 out
of 13 in the Crystal Structure of Mouse Csad
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 7 of Crystal Structure of Mouse Csad within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Cl506
b:27.3
occ:1.00
|
H
|
B:LEU93
|
2.4
|
37.8
|
1.0
|
|
HE21
|
B:GLN92
|
2.5
|
33.8
|
1.0
|
|
HB2
|
B:LEU93
|
2.8
|
35.1
|
1.0
|
|
HB3
|
B:GLN92
|
2.8
|
48.5
|
1.0
|
|
O
|
D:HOH733
|
2.9
|
40.7
|
1.0
|
|
N
|
B:LEU93
|
3.3
|
31.5
|
1.0
|
|
HD1
|
B:PHE94
|
3.3
|
44.5
|
1.0
|
|
HE3
|
B:LLP305
|
3.3
|
46.8
|
1.0
|
|
NE2
|
B:GLN92
|
3.3
|
28.1
|
1.0
|
|
HG
|
B:LEU93
|
3.5
|
43.3
|
1.0
|
|
HE1
|
B:PHE94
|
3.5
|
47.0
|
1.0
|
|
CB
|
B:LEU93
|
3.6
|
29.3
|
1.0
|
|
HE22
|
B:GLN92
|
3.6
|
33.8
|
1.0
|
|
CB
|
B:GLN92
|
3.8
|
40.4
|
1.0
|
|
HD12
|
B:LEU93
|
3.9
|
43.2
|
1.0
|
|
CA
|
B:LEU93
|
3.9
|
34.5
|
1.0
|
|
CD1
|
B:PHE94
|
4.0
|
37.1
|
1.0
|
|
HA
|
B:GLN92
|
4.0
|
45.1
|
1.0
|
|
CG
|
B:LEU93
|
4.0
|
36.1
|
1.0
|
|
H
|
B:PHE94
|
4.0
|
43.0
|
1.0
|
|
O
|
B:HOH634
|
4.1
|
37.0
|
1.0
|
|
CE1
|
B:PHE94
|
4.1
|
39.2
|
1.0
|
|
CA
|
B:GLN92
|
4.2
|
37.6
|
1.0
|
|
C
|
B:GLN92
|
4.2
|
34.7
|
1.0
|
|
CE
|
B:LLP305
|
4.3
|
39.0
|
1.0
|
|
HB2
|
B:GLN92
|
4.4
|
48.5
|
1.0
|
|
CD
|
B:GLN92
|
4.4
|
30.4
|
1.0
|
|
HB3
|
B:LEU93
|
4.4
|
35.1
|
1.0
|
|
CD1
|
B:LEU93
|
4.5
|
36.0
|
1.0
|
|
N
|
B:PHE94
|
4.5
|
35.8
|
1.0
|
|
C
|
B:LEU93
|
4.5
|
37.8
|
1.0
|
|
CG
|
B:GLN92
|
4.5
|
34.9
|
1.0
|
|
HG3
|
B:GLN92
|
4.6
|
41.9
|
1.0
|
|
HG3
|
B:LLP305
|
4.6
|
47.8
|
1.0
|
|
HE2
|
B:LLP305
|
4.6
|
46.8
|
1.0
|
|
H4'1
|
B:LLP305
|
4.7
|
47.2
|
1.0
|
|
O
|
B:HOH654
|
4.8
|
43.5
|
1.0
|
|
HA
|
B:LEU93
|
4.8
|
41.3
|
1.0
|
|
NZ
|
B:LLP305
|
4.9
|
40.5
|
1.0
|
|
HD13
|
B:LEU93
|
4.9
|
43.2
|
1.0
|
|
HH22
|
B:ARG466
|
5.0
|
39.7
|
1.0
|
|
Chlorine binding site 8 out
of 13 in 6zek
Go back to
Chlorine Binding Sites List in 6zek
Chlorine binding site 8 out
of 13 in the Crystal Structure of Mouse Csad
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 8 of Crystal Structure of Mouse Csad within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl504
b:20.2
occ:1.00
|
HE22
|
A:GLN312
|
2.4
|
31.1
|
1.0
|
|
H
|
C:ARG359
|
2.5
|
38.1
|
1.0
|
|
HE21
|
C:GLN355
|
2.6
|
35.2
|
1.0
|
|
HG3
|
C:ARG359
|
3.0
|
50.7
|
1.0
|
|
HB3
|
C:PRO150
|
3.1
|
35.3
|
1.0
|
|
HG3
|
A:GLN312
|
3.2
|
42.6
|
1.0
|
|
NE2
|
A:GLN312
|
3.3
|
25.9
|
1.0
|
|
HA
|
C:ARG358
|
3.3
|
42.5
|
1.0
|
|
HB2
|
C:ARG359
|
3.3
|
46.8
|
1.0
|
|
HD3
|
C:ARG359
|
3.3
|
49.0
|
1.0
|
|
N
|
C:ARG359
|
3.4
|
31.8
|
1.0
|
|
NE2
|
C:GLN355
|
3.4
|
29.4
|
1.0
|
|
HG3
|
C:ARG358
|
3.4
|
51.7
|
1.0
|
|
HB2
|
A:PRO150
|
3.6
|
28.1
|
1.0
|
|
CG
|
C:ARG359
|
3.7
|
42.3
|
1.0
|
|
HE21
|
A:GLN312
|
3.8
|
31.1
|
1.0
|
|
HE22
|
C:GLN355
|
3.8
|
35.2
|
1.0
|
|
CB
|
C:ARG359
|
3.8
|
39.0
|
1.0
|
|
CG
|
A:GLN312
|
4.0
|
35.5
|
1.0
|
|
CD
|
C:ARG359
|
4.0
|
40.8
|
1.0
|
|
CB
|
C:PRO150
|
4.0
|
29.4
|
1.0
|
|
HG2
|
A:GLN312
|
4.1
|
42.6
|
1.0
|
|
CD
|
A:GLN312
|
4.1
|
35.7
|
1.0
|
|
CA
|
C:ARG358
|
4.1
|
35.4
|
1.0
|
|
HD3
|
C:PRO150
|
4.2
|
32.8
|
1.0
|
|
CA
|
C:ARG359
|
4.2
|
29.8
|
1.0
|
|
C
|
C:ARG358
|
4.3
|
30.5
|
1.0
|
|
HG3
|
C:PRO150
|
4.3
|
32.5
|
1.0
|
|
CD
|
C:GLN355
|
4.4
|
28.6
|
1.0
|
|
CG
|
C:ARG358
|
4.4
|
43.1
|
1.0
|
|
CB
|
A:PRO150
|
4.4
|
23.4
|
1.0
|
|
HB3
|
A:PRO150
|
4.4
|
28.1
|
1.0
|
|
OE1
|
C:GLN355
|
4.4
|
34.2
|
1.0
|
|
HD2
|
C:ARG359
|
4.5
|
49.0
|
1.0
|
|
HB2
|
C:PRO150
|
4.5
|
35.3
|
1.0
|
|
HG2
|
C:ARG359
|
4.6
|
50.7
|
1.0
|
|
CG
|
C:PRO150
|
4.6
|
27.1
|
1.0
|
|
HA
|
C:PRO150
|
4.6
|
37.0
|
1.0
|
|
O
|
A:PRO150
|
4.7
|
25.8
|
1.0
|
|
HA
|
A:PRO150
|
4.7
|
29.5
|
1.0
|
|
CB
|
C:ARG358
|
4.7
|
36.1
|
1.0
|
|
HB3
|
C:ARG359
|
4.7
|
46.8
|
1.0
|
|
HG2
|
C:ARG358
|
4.8
|
51.7
|
1.0
|
|
CD
|
C:PRO150
|
4.8
|
27.3
|
1.0
|
|
CA
|
C:PRO150
|
4.9
|
30.8
|
1.0
|
|
C
|
A:PRO150
|
4.9
|
28.7
|
1.0
|
|
CA
|
A:PRO150
|
4.9
|
24.6
|
1.0
|
|
HA
|
C:ARG359
|
4.9
|
35.8
|
1.0
|
|
HB2
|
C:ARG358
|
4.9
|
43.3
|
1.0
|
|
O
|
C:GLY357
|
5.0
|
35.6
|
1.0
|
|
OD2
|
C:ASP361
|
5.0
|
33.5
|
1.0
|
|
Chlorine binding site 9 out
of 13 in 6zek
Go back to
Chlorine Binding Sites List in 6zek
Chlorine binding site 9 out
of 13 in the Crystal Structure of Mouse Csad
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 9 of Crystal Structure of Mouse Csad within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl505
b:40.9
occ:1.00
|
HZ3
|
C:LYS134
|
2.8
|
48.6
|
1.0
|
|
HE2
|
C:LYS134
|
2.9
|
39.5
|
1.0
|
|
HA3
|
C:GLY374
|
2.9
|
41.3
|
1.0
|
|
HE1
|
C:TRP369
|
3.0
|
41.2
|
1.0
|
|
NZ
|
C:LYS134
|
3.4
|
40.5
|
1.0
|
|
CE
|
C:LYS134
|
3.4
|
33.0
|
1.0
|
|
HA
|
A:SER62
|
3.5
|
39.7
|
1.0
|
|
C
|
A:GLN61
|
3.5
|
34.3
|
1.0
|
|
HZ2
|
C:TRP369
|
3.5
|
41.4
|
1.0
|
|
HE3
|
C:LYS134
|
3.6
|
39.5
|
1.0
|
|
H
|
C:GLY374
|
3.6
|
37.0
|
1.0
|
|
O
|
A:GLN61
|
3.6
|
31.5
|
1.0
|
|
CA
|
C:GLY374
|
3.6
|
34.4
|
1.0
|
|
HZ2
|
C:LYS134
|
3.7
|
48.6
|
1.0
|
|
NE1
|
C:TRP369
|
3.7
|
34.3
|
1.0
|
|
HA2
|
C:GLY374
|
3.8
|
41.3
|
1.0
|
|
HA
|
A:GLN61
|
3.8
|
40.9
|
1.0
|
|
N
|
A:SER62
|
3.8
|
34.6
|
1.0
|
|
N
|
C:GLY374
|
4.0
|
30.8
|
1.0
|
|
CA
|
A:GLN61
|
4.0
|
34.1
|
1.0
|
|
N
|
A:GLN61
|
4.1
|
29.6
|
1.0
|
|
CA
|
A:SER62
|
4.1
|
33.1
|
1.0
|
|
HZ1
|
C:LYS134
|
4.2
|
48.6
|
1.0
|
|
CZ2
|
C:TRP369
|
4.2
|
34.5
|
1.0
|
|
H
|
A:SER62
|
4.2
|
41.5
|
1.0
|
|
H
|
A:GLN61
|
4.3
|
35.6
|
1.0
|
|
HB3
|
A:LEU60
|
4.3
|
41.8
|
1.0
|
|
CE2
|
C:TRP369
|
4.3
|
31.9
|
1.0
|
|
C
|
A:LEU60
|
4.4
|
32.7
|
1.0
|
|
O
|
A:LEU60
|
4.4
|
34.4
|
1.0
|
|
HB2
|
A:SER62
|
4.6
|
45.2
|
1.0
|
|
HB2
|
A:LEU60
|
4.8
|
41.8
|
1.0
|
|
CD
|
C:LYS134
|
4.9
|
39.4
|
1.0
|
|
CD1
|
C:TRP369
|
4.9
|
28.9
|
1.0
|
|
C
|
C:GLY374
|
4.9
|
34.4
|
1.0
|
|
CB
|
A:SER62
|
4.9
|
37.6
|
1.0
|
|
CB
|
A:LEU60
|
5.0
|
34.8
|
1.0
|
|
Chlorine binding site 10 out
of 13 in 6zek
Go back to
Chlorine Binding Sites List in 6zek
Chlorine binding site 10 out
of 13 in the Crystal Structure of Mouse Csad
 Mono view
 Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 10 of Crystal Structure of Mouse Csad within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl506
b:23.3
occ:1.00
|
H
|
C:LEU93
|
2.4
|
36.7
|
1.0
|
|
HB2
|
C:LEU93
|
2.9
|
33.4
|
1.0
|
|
HB3
|
C:GLN92
|
2.9
|
33.0
|
1.0
|
|
HE21
|
C:GLN92
|
2.9
|
36.1
|
1.0
|
|
N
|
C:LEU93
|
3.2
|
30.6
|
1.0
|
|
HE3
|
C:LLP305
|
3.3
|
35.8
|
1.0
|
|
HD1
|
C:PHE94
|
3.4
|
34.5
|
1.0
|
|
HG
|
C:LEU93
|
3.4
|
36.5
|
1.0
|
|
CB
|
C:LEU93
|
3.6
|
27.8
|
1.0
|
|
O
|
C:HOH754
|
3.7
|
31.0
|
1.0
|
|
NE2
|
C:GLN92
|
3.7
|
30.1
|
1.0
|
|
CB
|
C:GLN92
|
3.8
|
27.5
|
1.0
|
|
O
|
A:HOH768
|
3.9
|
36.0
|
1.0
|
|
HE1
|
C:PHE94
|
3.9
|
46.8
|
1.0
|
|
CA
|
C:LEU93
|
3.9
|
27.9
|
1.0
|
|
CG
|
C:LEU93
|
3.9
|
30.4
|
1.0
|
|
HD12
|
C:LEU93
|
4.0
|
36.3
|
1.0
|
|
HE22
|
C:GLN92
|
4.0
|
36.1
|
1.0
|
|
CD1
|
C:PHE94
|
4.1
|
28.7
|
1.0
|
|
HA
|
C:GLN92
|
4.1
|
30.0
|
1.0
|
|
H
|
C:PHE94
|
4.1
|
30.0
|
1.0
|
|
CE
|
C:LLP305
|
4.2
|
29.8
|
1.0
|
|
O
|
C:HOH756
|
4.2
|
43.0
|
1.0
|
|
C
|
C:GLN92
|
4.3
|
32.6
|
1.0
|
|
HE2
|
C:LLP305
|
4.3
|
35.8
|
1.0
|
|
HB2
|
C:GLN92
|
4.3
|
33.0
|
1.0
|
|
CA
|
C:GLN92
|
4.3
|
25.0
|
1.0
|
|
CE1
|
C:PHE94
|
4.3
|
39.0
|
1.0
|
|
C
|
C:LEU93
|
4.4
|
32.5
|
1.0
|
|
HB3
|
C:LEU93
|
4.5
|
33.4
|
1.0
|
|
HG3
|
C:LLP305
|
4.5
|
35.3
|
1.0
|
|
CD1
|
C:LEU93
|
4.5
|
30.3
|
1.0
|
|
N
|
C:PHE94
|
4.5
|
25.0
|
1.0
|
|
CD
|
C:GLN92
|
4.7
|
26.7
|
1.0
|
|
CG
|
C:GLN92
|
4.7
|
21.0
|
1.0
|
|
HA
|
C:LEU93
|
4.8
|
33.5
|
1.0
|
|
HG3
|
C:GLN92
|
4.8
|
25.2
|
1.0
|
|
NZ
|
C:LLP305
|
4.8
|
35.5
|
1.0
|
|
HH22
|
C:ARG466
|
5.0
|
34.7
|
1.0
|
|
Reference:
E.Mahootchi,
A.Raasakka,
W.Luan,
G.Muruganandam,
R.Loris,
J.Haavik,
P.Kursula.
Structure and Substrate Specificity Determinants of the Taurine Biosynthetic Enzyme Cysteine Sulphinic Acid Decarboxylase. J.Struct.Biol. V. 213 07674 2021.
ISSN: ESSN 1095-8657
PubMed: 33253877
DOI: 10.1016/J.JSB.2020.107674
Page generated: Sat Jul 10 12:27:19 2021
|
