Chlorine in PDB 6zeq: Aspergillus Oryzae Leucine Aminopeptidase A Mature Enzyme

The structure of Aspergillus Oryzae Leucine Aminopeptidase A Mature Enzyme, PDB code: 6zeq was solved by K.A.Watson, G.Baltulionis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	73.81 / 1.97
Space group	P 63 2 2
Cell size a, b, c (Å), α, β, γ (°)	153.92, 153.92, 88.64, 90, 90, 120
R / Rfree (%)	16.5 / 20.4

The structure of Aspergillus Oryzae Leucine Aminopeptidase A Mature Enzyme also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Chlorine atom in the Aspergillus Oryzae Leucine Aminopeptidase A Mature Enzyme (pdb code 6zeq). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Aspergillus Oryzae Leucine Aminopeptidase A Mature Enzyme, PDB code: 6zeq:

Chlorine binding site 1 out of 1 in the Aspergillus Oryzae Leucine Aminopeptidase A Mature Enzyme


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Aspergillus Oryzae Leucine Aminopeptidase A Mature Enzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:62.5 occ:0.85 O A:HOH660 2.1 34.8 1.0 O A:HOH699 2.3 47.3 1.0 O A:HOH553 2.4 40.1 1.0 ZN A:ZN402 2.8 31.9 1.0 O A:HOH915 2.9 50.4 1.0 O A:HOH671 3.2 48.9 1.0 ZN A:ZN401 3.4 28.8 1.0 OD2 A:ASP195 3.5 24.7 1.0 NE2 A:HIS343 3.8 31.1 1.0 O A:HOH906 3.9 51.3 1.0 CE1 A:HIS343 4.0 30.6 1.0 O A:HOH825 4.1 61.7 1.0 CG A:ASP195 4.1 29.1 1.0 OD1 A:ASP195 4.2 28.3 1.0 O A:CYS314 4.2 37.7 1.0 OD2 A:ASP261 4.4 25.0 1.0 O A:HOH670 4.5 60.6 1.0 CD1 A:ILE342 4.5 31.5 1.0 OE2 A:GLU233 4.5 35.5 1.0 OE1 A:GLU234 4.6 32.1 1.0 OE2 A:GLU234 4.6 27.6 1.0 O A:HOH747 4.7 53.0 1.0 SD A:MET262 4.8 33.1 1.0 O A:HOH896 4.8 56.9 1.0 OE1 A:GLU233 4.8 29.1 1.0 OH A:TYR312 4.9 41.4 1.0

G.Baltulionis, M.Blight, A.Robin, D.Charalampopoulos, K.A.Watson. The Role of Propeptide-Mediated Autoinhibition and Intermolecular Chaperone in the Maturation of Cognate Catalytic Domain in Leucine Aminopeptidase. J.Struct.Biol. V. 213 07741 2021.
ISSN: ESSN 1095-8657
PubMed: 33989771
DOI: 10.1016/J.JSB.2021.107741