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Chlorine in PDB 6zxi: Crystal Structure of the Oxa-48 Carbapenem-Hydrolyzing Class D Beta- Lactamase in Complex with the Dbo Inhibitor ANT3310Enzymatic activity of Crystal Structure of the Oxa-48 Carbapenem-Hydrolyzing Class D Beta- Lactamase in Complex with the Dbo Inhibitor ANT3310
All present enzymatic activity of Crystal Structure of the Oxa-48 Carbapenem-Hydrolyzing Class D Beta- Lactamase in Complex with the Dbo Inhibitor ANT3310:
3.5.2.6; Protein crystallography data
The structure of Crystal Structure of the Oxa-48 Carbapenem-Hydrolyzing Class D Beta- Lactamase in Complex with the Dbo Inhibitor ANT3310, PDB code: 6zxi
was solved by
J.D.Docquier,
C.Pozzi,
F.De Luca,
M.Benvenuti,
S.Mangani,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6zxi:
The structure of Crystal Structure of the Oxa-48 Carbapenem-Hydrolyzing Class D Beta- Lactamase in Complex with the Dbo Inhibitor ANT3310 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the Oxa-48 Carbapenem-Hydrolyzing Class D Beta- Lactamase in Complex with the Dbo Inhibitor ANT3310
(pdb code 6zxi). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Oxa-48 Carbapenem-Hydrolyzing Class D Beta- Lactamase in Complex with the Dbo Inhibitor ANT3310, PDB code: 6zxi: Chlorine binding site 1 out of 1 in 6zxiGo back to Chlorine Binding Sites List in 6zxi
Chlorine binding site 1 out
of 1 in the Crystal Structure of the Oxa-48 Carbapenem-Hydrolyzing Class D Beta- Lactamase in Complex with the Dbo Inhibitor ANT3310
Mono view Stereo pair view
Reference:
D.T.Davies,
S.Leiris,
N.Sprynski,
J.Castandet,
C.Lozano,
J.Bousquet,
M.Zalacain,
F.Marcoccia,
M.Benvenuti,
C.Pozzi,
S.Mangani,
J.D.Docquier,
M.Lemonnier,
M.Everett.
Discovery of Sodium (2R,5R)-2-Fluoro-7-Oxo-1,6-Diazabicyclo[3.2.1]Octan-6-Yl Sulphate (ANT3310), A Novel Broad-Spectrum Serine Beta-Lactamase Inhibitor of the Diazabicyclooctane Class, Differentiated By Additional Activity in Combination with Meropenem Against the Who Priority Pathogens Carbapenem Resistant Acinetobacter Baumannii (Crab) To Be Published.
Page generated: Sat Aug 21 13:09:34 2021
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