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Chlorine in PDB 7a13: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GSK1978537A (Compound 27)Enzymatic activity of Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GSK1978537A (Compound 27)
All present enzymatic activity of Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GSK1978537A (Compound 27):
3.4.11.18; Protein crystallography data
The structure of Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GSK1978537A (Compound 27), PDB code: 7a13
was solved by
J.H.Thorpe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7a13:
The structure of Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GSK1978537A (Compound 27) also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GSK1978537A (Compound 27)
(pdb code 7a13). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GSK1978537A (Compound 27), PDB code: 7a13: Chlorine binding site 1 out of 1 in 7a13Go back to Chlorine Binding Sites List in 7a13
Chlorine binding site 1 out
of 1 in the Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GSK1978537A (Compound 27)
Mono view Stereo pair view
Reference:
D.J.Hirst,
M.Brandt,
G.Bruton,
E.Christodoulou,
L.Cutler,
N.Deeks,
J.D.Goodacre,
T.Jack,
M.Lindon,
A.Miah,
K.Page,
N.Parr,
L.Shukla,
M.Sims,
P.Thomas,
J.Thorpe,
D.S.Holmes.
Structure-Based Optimisation of Orally Active & Reversible Metap-2 Inhibitors Maintaining A Tight 'Molecular Budget'. Bioorg.Med.Chem.Lett. V. 30 27533 2020.
Page generated: Sat Dec 12 14:49:00 2020
ISSN: ESSN 1464-3405 PubMed: 32919012 DOI: 10.1016/J.BMCL.2020.127533 |
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