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Chlorine in PDB 7a5n: Structure of DYRK1A in Complex with Compound 34Enzymatic activity of Structure of DYRK1A in Complex with Compound 34
All present enzymatic activity of Structure of DYRK1A in Complex with Compound 34:
2.7.12.1; Protein crystallography data
The structure of Structure of DYRK1A in Complex with Compound 34, PDB code: 7a5n
was solved by
P.Dokurno,
A.E.Surgenor,
R.E.Hubbard,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7a5n:
The structure of Structure of DYRK1A in Complex with Compound 34 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of DYRK1A in Complex with Compound 34
(pdb code 7a5n). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of DYRK1A in Complex with Compound 34, PDB code: 7a5n: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 7a5nGo back to Chlorine Binding Sites List in 7a5n
Chlorine binding site 1 out
of 3 in the Structure of DYRK1A in Complex with Compound 34
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 7a5nGo back to Chlorine Binding Sites List in 7a5n
Chlorine binding site 2 out
of 3 in the Structure of DYRK1A in Complex with Compound 34
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 7a5nGo back to Chlorine Binding Sites List in 7a5n
Chlorine binding site 3 out
of 3 in the Structure of DYRK1A in Complex with Compound 34
Mono view Stereo pair view
Reference:
D.Lee Walmsley,
J.B.Murray,
P.Dokurno,
A.J.Massey,
K.Benwell,
A.Fiumana,
N.Foloppe,
S.Ray,
J.Smith,
A.E.Surgenor,
T.Edmonds,
D.Demarles,
M.Burbridge,
F.Cruzalegui,
A.Kotschy,
R.E.Hubbard.
Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B. J.Med.Chem. 2021.
Page generated: Sat Jul 10 12:29:43 2021
ISSN: ISSN 0022-2623 PubMed: 34143631 DOI: 10.1021/ACS.JMEDCHEM.1C00024 |
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