Chlorine in PDB 7aen: Galectin-8 N-Terminal Carbohydrate Recognition Domain in Complex with Methyl 3-O-((7-Carboxy)Quinolin-2-Yl)-Methoxy)-Beta-D- Galactopyranoside

The structure of Galectin-8 N-Terminal Carbohydrate Recognition Domain in Complex with Methyl 3-O-((7-Carboxy)Quinolin-2-Yl)-Methoxy)-Beta-D- Galactopyranoside, PDB code: 7aen was solved by M.Hassan, V.S.Klavern, M.Hakansson, M.Anderluh, T.Tomasic, Z.Jakopin, J.U.Nilsson, R.Kovacic, B.Walse, C.Diehl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.57 / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	54.452, 61.124, 84.712, 90, 90, 90
R / Rfree (%)	13.9 / 21.2

The binding sites of Chlorine atom in the Galectin-8 N-Terminal Carbohydrate Recognition Domain in Complex with Methyl 3-O-((7-Carboxy)Quinolin-2-Yl)-Methoxy)-Beta-D- Galactopyranoside (pdb code 7aen). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Galectin-8 N-Terminal Carbohydrate Recognition Domain in Complex with Methyl 3-O-((7-Carboxy)Quinolin-2-Yl)-Methoxy)-Beta-D- Galactopyranoside, PDB code: 7aen:

Chlorine binding site 1 out of 1 in the Galectin-8 N-Terminal Carbohydrate Recognition Domain in Complex with Methyl 3-O-((7-Carboxy)Quinolin-2-Yl)-Methoxy)-Beta-D- Galactopyranoside


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Galectin-8 N-Terminal Carbohydrate Recognition Domain in Complex with Methyl 3-O-((7-Carboxy)Quinolin-2-Yl)-Methoxy)-Beta-D- Galactopyranoside within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl203 b:38.2 occ:1.00 NZ A:LYS113 3.1 46.7 1.0 N B:GLY131 3.2 26.1 1.0 N A:ASP112 3.2 32.9 1.0 CB A:ASP112 3.5 33.7 1.0 NZ B:LYS134 3.5 46.7 1.0 CB A:LEU110 3.8 26.4 1.0 CA A:ASP112 3.8 28.5 1.0 N A:LYS111 3.9 28.3 1.0 CA B:GLY131 4.0 29.0 1.0 OD2 A:ASP112 4.0 44.2 1.0 CG A:ASP112 4.1 40.0 1.0 CE A:LYS113 4.1 47.0 1.0 CB A:LYS111 4.2 27.4 1.0 C B:ILE130 4.2 23.4 1.0 N A:LYS113 4.2 26.1 1.0 CA B:ILE130 4.2 23.2 1.0 C A:LYS111 4.2 27.8 1.0 CG A:LYS113 4.3 33.8 1.0 C A:ASP112 4.3 27.6 1.0 CA A:LYS111 4.4 26.5 1.0 CG2 B:ILE130 4.4 29.5 1.0 CD1 A:LEU110 4.5 28.8 1.0 C A:LEU110 4.5 29.0 1.0 CG B:LYS134 4.5 32.3 1.0 CE B:LYS134 4.6 41.5 1.0 OE2 B:GLU133 4.6 30.2 1.0 CG A:LEU110 4.8 23.1 1.0 CA A:LEU110 4.8 27.6 1.0 CD A:LYS113 4.8 39.2 1.0 CB B:ILE130 4.9 24.4 1.0 CD B:LYS134 5.0 36.4 1.0

M.Hassan, M.Hakansson, U.Nilsson. Crystal Structure of the Galectin-8 N-Terminal Carbohydrate Recognition Domain in Complex with the Quinoline-Galactoside Ligand To Be Published.