Chlorine in PDB 7afz: L1 Metallo-B-Lactamase with Compound Ebl-1306

All present enzymatic activity of L1 Metallo-B-Lactamase with Compound Ebl-1306:
3.5.2.6;

The structure of L1 Metallo-B-Lactamase with Compound Ebl-1306, PDB code: 7afz was solved by P.Hinchliffe, J.Spencer, J.Brem, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	66.62 / 1.50
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	104.78, 104.78, 98.11, 90, 90, 120
R / Rfree (%)	15.2 / 16.8

The structure of L1 Metallo-B-Lactamase with Compound Ebl-1306 also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Chlorine atom in the L1 Metallo-B-Lactamase with Compound Ebl-1306 (pdb code 7afz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the L1 Metallo-B-Lactamase with Compound Ebl-1306, PDB code: 7afz:

Chlorine binding site 1 out of 1 in the L1 Metallo-B-Lactamase with Compound Ebl-1306


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of L1 Metallo-B-Lactamase with Compound Ebl-1306 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl303 b:57.7 occ:1.00 CL1 A:RBW303 0.0 57.7 1.0 C25 A:RBW303 1.8 57.9 1.0 C27 A:RBW303 2.7 51.8 1.0 H271 A:RBW303 2.7 62.1 1.0 C19 A:RBW303 2.7 63.3 1.0 H201 A:RBW303 2.9 87.2 1.0 HB3 A:HIS225 3.0 19.4 1.0 O23 A:RBW303 3.0 81.7 1.0 C20 A:RBW303 3.1 72.7 1.0 HB2 A:HIS225 3.3 19.4 1.0 CB A:HIS225 3.5 16.2 1.0 HB2 A:ALA228 3.7 22.8 1.0 S21 A:RBW303 3.7 80.2 1.0 O A:HOH485 3.8 19.9 1.0 O A:HOH631 3.9 46.2 1.0 C18 A:RBW303 4.0 57.8 1.0 H A:ALA228 4.0 19.8 1.0 C16 A:RBW303 4.0 46.4 1.0 H202 A:RBW303 4.0 87.2 1.0 CG A:HIS225 4.0 17.1 1.0 O A:HOH523 4.3 22.9 1.0 N A:ALA228 4.3 16.5 1.0 H221 A:RBW303 4.3 97.2 1.0 C17 A:RBW303 4.5 52.1 1.0 ND1 A:HIS225 4.5 19.7 1.0 HD1 A:HIS225 4.5 23.7 1.0 CB A:ALA228 4.5 19.0 1.0 HA A:ALA228 4.5 20.8 1.0 C22 A:RBW303 4.6 81.0 1.0 HA3 A:GLY227 4.6 24.5 1.0 O A:HOH423 4.7 20.6 1.0 H181 A:RBW303 4.7 69.4 1.0 CA A:ALA228 4.7 17.3 1.0 CD2 A:HIS225 4.8 15.6 1.0 H A:GLY227 4.8 19.6 1.0 C A:GLY227 4.9 19.3 1.0 CA A:HIS225 4.9 15.8 1.0 O24 A:RBW303 4.9 81.4 1.0 O A:HIS225 4.9 15.8 1.0 HB3 A:ALA228 5.0 22.8 1.0

P.Hinchliffe, J.Spencer, J.Brem. L1 Metallo-B-Lactamase with Compound Ebl-1306 To Be Published.