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Chlorine in PDB 7aj7: Structure of DYRK1A in Complex with Compound 16Enzymatic activity of Structure of DYRK1A in Complex with Compound 16
All present enzymatic activity of Structure of DYRK1A in Complex with Compound 16:
2.7.12.1; Protein crystallography data
The structure of Structure of DYRK1A in Complex with Compound 16, PDB code: 7aj7
was solved by
P.Dokurno,
A.E.Surgenor,
A.Kotschy,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of DYRK1A in Complex with Compound 16
(pdb code 7aj7). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of DYRK1A in Complex with Compound 16, PDB code: 7aj7: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 7aj7Go back to Chlorine Binding Sites List in 7aj7
Chlorine binding site 1 out
of 2 in the Structure of DYRK1A in Complex with Compound 16
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 7aj7Go back to Chlorine Binding Sites List in 7aj7
Chlorine binding site 2 out
of 2 in the Structure of DYRK1A in Complex with Compound 16
Mono view Stereo pair view
Reference:
C.Weber,
M.Sipos,
A.Paczal,
B.Balint,
V.Kun,
N.Foloppe,
P.Dokurno,
A.J.Massey,
D.L.Walmsley,
R.E.Hubbard,
J.Murray,
K.Benwell,
T.Edmonds,
D.Demarles,
A.Bruno,
M.Burbridge,
F.Cruzalegui,
A.Kotschy.
Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors. J.Med.Chem. 2021.
Page generated: Sat Jul 10 12:31:30 2021
ISSN: ISSN 0022-2623 PubMed: 33975430 DOI: 10.1021/ACS.JMEDCHEM.1C00023 |
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