Atomistry » Chlorine » PDB 7apt-7avr » 7ass
Atomistry »
  Chlorine »
    PDB 7apt-7avr »
      7ass »

Chlorine in PDB 7ass: Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48

Enzymatic activity of Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48

All present enzymatic activity of Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48:
3.5.2.6;

Protein crystallography data

The structure of Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48, PDB code: 7ass was solved by C.Frohlich, H.-K.S.Leiros, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 23.56 / 1.91
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 88.555, 108.476, 125.423, 90.00, 90.00, 90.00
R / Rfree (%) 18.7 / 23

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48 (pdb code 7ass). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48, PDB code: 7ass:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in 7ass

Go back to Chlorine Binding Sites List in 7ass
Chlorine binding site 1 out of 5 in the Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl301

b:30.5
occ:1.00
 O B:HOH573 2.2 25.9 1.0
HH12 B:ARG206 2.2 19.4 1.0
HH22 D:ARG206 2.2 23.9 1.0
HH12 D:ARG206 2.3 26.5 1.0
HH22 B:ARG206 2.3 21.3 1.0
O D:HOH556 2.3 28.9 1.0
NH1 B:ARG206 3.0 16.1 1.0
NH2 D:ARG206 3.0 19.9 1.0
NH1 D:ARG206 3.0 22.1 1.0
NH2 B:ARG206 3.0 17.7 1.0
HD22 B:LEU196 3.2 22.7 1.0
HD22 D:LEU196 3.3 23.6 1.0
HA B:GLN193 3.4 20.5 1.0
HA D:GLN193 3.4 22.4 1.0
CZ D:ARG206 3.4 19.8 1.0
CZ B:ARG206 3.5 17.6 1.0
HG3 D:GLN193 3.5 21.2 1.0
HG3 B:GLN193 3.5 18.2 1.0
HH11 B:ARG206 3.7 19.4 1.0
HH21 D:ARG206 3.7 23.9 1.0
HH11 D:ARG206 3.7 26.5 1.0
HH21 B:ARG206 3.8 21.3 1.0
HB2 D:LEU196 4.1 18.9 1.0
HB2 B:LEU196 4.2 21.6 1.0
CD2 B:LEU196 4.2 18.9 1.0
HB2 B:GLN193 4.2 22.0 1.0
HB2 D:GLN193 4.3 20.5 1.0
CD2 D:LEU196 4.3 19.6 1.0
CA B:GLN193 4.3 17.1 1.0
CA D:GLN193 4.3 18.6 1.0
CG D:GLN193 4.4 17.7 1.0
CG B:GLN193 4.4 15.2 1.0
HD13 D:LEU196 4.4 19.8 1.0
HD23 B:LEU196 4.5 22.7 1.0
CB B:GLN193 4.5 18.3 1.0
HD13 B:LEU196 4.5 20.4 1.0
CB D:GLN193 4.5 17.0 1.0
HD21 B:LEU196 4.6 22.7 1.0
HD23 D:LEU196 4.7 23.6 1.0
HD21 D:LEU196 4.7 23.6 1.0
O B:HOH452 4.7 32.9 1.0
NE D:ARG206 4.8 17.7 1.0
NE B:ARG206 4.8 19.7 1.0
O D:HOH465 4.9 28.7 1.0
HG2 D:GLN193 4.9 21.2 1.0
HG2 B:GLN193 4.9 18.2 1.0
CB D:LEU196 5.0 15.7 1.0
CB B:LEU196 5.0 18.0 1.0
O D:HOH557 5.0 26.5 1.0

Chlorine binding site 2 out of 5 in 7ass

Go back to Chlorine Binding Sites List in 7ass
Chlorine binding site 2 out of 5 in the Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl302

b:29.2
occ:1.00
 O A:HOH451 2.2 26.1 1.0
HH12 A:ARG206 2.3 23.3 1.0
O C:HOH560 2.3 27.7 1.0
HH22 C:ARG206 2.3 28.0 1.0
HH12 C:ARG206 2.3 25.3 1.0
HH22 A:ARG206 2.3 24.7 1.0
NH2 C:ARG206 3.0 23.3 1.0
NH1 C:ARG206 3.0 21.1 1.0
NH1 A:ARG206 3.1 19.4 1.0
NH2 A:ARG206 3.1 20.5 1.0
HA C:GLN193 3.4 20.8 1.0
HD22 C:LEU196 3.4 27.5 1.0
HD22 A:LEU196 3.4 24.1 1.0
HA A:GLN193 3.4 19.9 1.0
CZ C:ARG206 3.5 24.8 1.0
HG3 A:GLN193 3.5 27.3 1.0
CZ A:ARG206 3.5 22.5 1.0
HG3 C:GLN193 3.7 22.4 1.0
HH21 C:ARG206 3.7 28.0 1.0
HH11 A:ARG206 3.7 23.3 1.0
HH11 C:ARG206 3.7 25.3 1.0
HH21 A:ARG206 3.8 24.7 1.0
HB2 C:GLN193 4.0 18.8 1.0
HB2 C:LEU196 4.1 20.8 1.0
HB2 A:LEU196 4.1 23.4 1.0
HB2 A:GLN193 4.2 21.3 1.0
CA C:GLN193 4.2 17.3 1.0
CA A:GLN193 4.3 16.5 1.0
CD2 C:LEU196 4.3 22.9 1.0
CG A:GLN193 4.3 22.7 1.0
CD2 A:LEU196 4.4 20.1 1.0
CB C:GLN193 4.4 15.7 1.0
CG C:GLN193 4.5 18.6 1.0
CB A:GLN193 4.5 17.7 1.0
HD13 C:LEU196 4.5 23.6 1.0
HD13 A:LEU196 4.6 18.9 1.0
HD23 C:LEU196 4.7 27.5 1.0
O A:HOH369 4.7 32.1 1.0
HD23 A:LEU196 4.7 24.1 1.0
NE C:ARG206 4.8 14.5 1.0
HD21 A:LEU196 4.8 24.1 1.0
HD21 C:LEU196 4.8 27.5 1.0
O C:HOH446 4.8 31.8 1.0
NE A:ARG206 4.9 16.7 1.0
HG2 A:GLN193 4.9 27.3 1.0
CB C:LEU196 4.9 17.3 1.0
O C:HOH552 4.9 26.6 1.0
CB A:LEU196 5.0 19.5 1.0
O C:GLN193 5.0 19.2 1.0
O A:GLN193 5.0 16.2 1.0

Chlorine binding site 3 out of 5 in 7ass

Go back to Chlorine Binding Sites List in 7ass
Chlorine binding site 3 out of 5 in the Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl303

b:57.9
occ:1.00
 HH22 C:ARG250 2.3 34.7 1.0
O C:HOH511 2.4 43.9 1.0
O C:HOH568 2.7 45.8 1.0
HA2 C:GLY210 3.0 32.6 1.0
HB2 C:TYR211 3.2 35.4 1.0
HB C:THR209 3.2 29.6 1.0
NH2 C:ARG250 3.2 28.9 1.0
C C:GLY210 3.3 17.3 1.0
CA C:GLY210 3.4 27.2 1.0
HH12 C:ARG250 3.4 31.4 1.0
N C:GLY210 3.5 18.4 1.0
HG1 C:THR209 3.5 26.9 1.0
N C:TYR211 3.5 30.0 1.0
OG1 C:THR209 3.5 22.4 1.0
H C:TYR211 3.6 36.0 1.0
HH21 C:ARG250 3.6 34.7 1.0
H C:GLY210 3.7 22.1 1.0
HB3 C:TYR211 3.8 35.4 1.0
O C:GLY210 3.8 23.7 1.0
C C:THR209 3.8 22.0 1.0
CB C:THR209 3.8 24.7 1.0
HG C:SER118 3.8 48.2 1.0
CB C:TYR211 3.8 29.5 1.0
HB2 C:SER70 4.0 31.5 1.0
O C:HOH450 4.0 23.7 1.0
O C:HOH592 4.1 47.8 1.0
NH1 C:ARG250 4.1 26.1 1.0
CZ C:ARG250 4.1 27.0 1.0
O C:THR209 4.1 20.2 1.0
CA C:TYR211 4.3 27.7 1.0
HA3 C:GLY210 4.4 32.6 1.0
CA C:THR209 4.5 23.0 1.0
HD13 C:LEU247 4.6 39.4 1.0
OG C:SER118 4.6 40.2 1.0
HZ3 C:LYS208 4.7 29.4 1.0
HB2 C:SER118 4.8 29.2 1.0
HA C:TYR211 4.8 33.3 1.0
CB C:SER70 4.8 26.2 1.0
HH11 C:ARG250 4.9 31.4 1.0
HZ1 C:LYS208 4.9 29.4 1.0
O C:HOH503 4.9 30.0 1.0
HD22 C:LEU247 5.0 44.4 1.0

Chlorine binding site 4 out of 5 in 7ass

Go back to Chlorine Binding Sites List in 7ass
Chlorine binding site 4 out of 5 in the Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl304

b:59.9
occ:1.00
 HE22 C:GLN124 2.3 36.9 1.0
HH22 C:ARG214 2.5 45.2 1.0
HH12 C:ARG214 2.5 28.5 1.0
NE2 C:GLN124 3.1 30.7 1.0
NH2 C:ARG214 3.3 37.6 1.0
NH1 C:ARG214 3.3 23.8 1.0
HE21 C:GLN124 3.3 36.9 1.0
HN18 C:RYE301 3.7 47.1 1.0
CZ C:ARG214 3.8 42.1 1.0
HB2 C:SER155 3.9 42.2 1.0
HH21 C:ARG214 4.0 45.2 1.0
O C:HOH411 4.0 77.6 1.0
HH11 C:ARG214 4.0 28.5 1.0
HB3 C:SER155 4.1 42.2 1.0
CD C:GLN124 4.2 34.6 1.0
S16 C:RYE301 4.3 47.9 1.0
C17 C:RYE301 4.3 55.3 1.0
N18 C:RYE301 4.3 39.2 1.0
CB C:SER155 4.5 35.2 1.0
OE1 C:GLN124 4.5 30.2 1.0
O C:HOH545 4.7 44.5 1.0
O C:ASP154 4.9 27.2 1.0
O C:HOH430 4.9 30.0 1.0
N19 C:RYE301 4.9 38.1 1.0
C15 C:RYE301 4.9 45.9 1.0

Chlorine binding site 5 out of 5 in 7ass

Go back to Chlorine Binding Sites List in 7ass
Chlorine binding site 5 out of 5 in the Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Oxa-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl302

b:57.0
occ:1.00
 HH22 D:ARG250 2.2 37.5 1.0
NH2 D:ARG250 3.1 31.2 1.0
HB2 D:TYR211 3.1 39.2 1.0
HA2 D:GLY210 3.2 24.8 1.0
HH12 D:ARG250 3.2 40.3 1.0
HB D:THR209 3.3 29.1 1.0
HG1 D:THR209 3.4 28.8 1.0
OG1 D:THR209 3.5 24.0 1.0
HG D:SER118 3.5 29.2 0.7
HH21 D:ARG250 3.6 37.5 1.0
C D:GLY210 3.6 22.1 1.0
CA D:GLY210 3.7 20.6 1.0
N D:TYR211 3.7 27.5 1.0
N D:GLY210 3.7 19.9 1.0
H D:TYR211 3.8 33.0 1.0
HB3 D:TYR211 3.8 39.2 1.0
NH1 D:ARG250 3.9 33.6 1.0
CB D:THR209 3.9 24.2 1.0
CB D:TYR211 3.9 32.6 1.0
CZ D:ARG250 3.9 32.5 1.0
O D:HOH418 3.9 36.4 1.0
C D:THR209 4.0 20.5 1.0
H D:GLY210 4.0 23.9 1.0
O D:GLY210 4.1 20.8 1.0
HB2 D:SER70 4.3 30.0 1.0
O D:THR209 4.3 20.6 1.0
OG D:SER118 4.3 24.3 0.7
O D:HOH461 4.4 24.8 1.0
CA D:TYR211 4.4 28.4 1.0
HD22 D:LEU247 4.4 46.6 1.0
OG D:SER118 4.6 20.2 0.3
HA3 D:GLY210 4.6 24.8 1.0
CA D:THR209 4.6 21.0 1.0
HB2 D:SER118 4.6 32.5 0.3
HH11 D:ARG250 4.7 40.3 1.0
HD13 D:LEU247 4.7 44.7 1.0
HB2 D:SER118 4.8 32.6 0.7
HB3 D:SER118 4.8 32.6 0.7
O D:HOH483 4.8 32.8 1.0
HB3 D:SER118 4.8 32.5 0.3
HA D:TYR211 4.9 34.2 1.0
HZ3 D:LYS208 4.9 23.3 1.0
CB D:SER118 4.9 27.2 0.7
CB D:SER118 4.9 27.1 0.3
HZ2 D:LYS208 4.9 23.3 1.0

Reference:

C.Frohlich, K.Harms, V.Hirvonen, B.A.Lund, M.V.Kamp, P.J.Johnsen, O.Samuelsen, H.-K.S.Leiros. What Doesnt Kill You Makes You Stronger: Sub-Mic Selection Drives Cryptic Evolution of Oxa-48 To Be Published.
Page generated: Mon Jul 29 18:41:39 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy