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Chlorine in PDB 7at9: Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine

Enzymatic activity of Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine

All present enzymatic activity of Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine:
2.7.11.1;

Protein crystallography data

The structure of Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine, PDB code: 7at9 was solved by D.Lindenblatt, V.Applegate, A.Nickelsen, M.Klussmann, I.Neundorf, C.Goetz, J.Jose, K.Niefind, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 43.74 / 1.05
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 46.482, 47.661, 50.733, 66.61, 89.44, 88.66
R / Rfree (%) 12.9 / 15

Other elements in 7at9:

The structure of Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine also contains other interesting chemical elements:

Bromine (Br) 8 atoms
Sodium (Na) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine (pdb code 7at9). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine, PDB code: 7at9:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in 7at9

Go back to Chlorine Binding Sites List in 7at9
Chlorine binding site 1 out of 6 in the Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl501

b:15.6
occ:1.00
 CL1 A:42J501 0.0 15.6 1.0
C6 A:42J501 1.7 13.4 1.0
C7 A:42J501 2.7 13.0 1.0
C5 A:42J501 2.7 14.5 1.0
H3 A:42J501 2.8 15.6 1.0
HE2 A:MET138 3.0 19.8 1.0
CL A:42J501 3.2 16.2 1.0
HB3 A:TYR137 3.2 13.3 1.0
HD21 A:LEU141 3.3 13.5 1.0
HA A:MET138 3.4 11.7 1.0
HE2 A:MET222 3.6 14.3 1.0
HB2 A:LEU141 3.6 12.0 1.0
HD12 A:LEU172 3.6 13.6 1.0
HD12 A:ILE165 3.6 16.2 1.0
HD23 A:LEU141 3.7 13.5 1.0
HG2 A:MET138 3.7 13.7 1.0
HG12 A:VAL163 3.7 15.5 1.0
O A:TYR137 3.7 10.7 1.0
CE A:MET138 3.8 16.5 1.0
C A:TYR137 3.8 9.6 1.0
HB2 A:TYR137 3.9 13.3 1.0
CB A:TYR137 3.9 11.1 1.0
CD2 A:LEU141 3.9 11.2 1.0
N A:MET138 3.9 9.5 1.0
C4 A:42J501 4.0 15.6 1.0
C2 A:42J501 4.0 13.3 1.0
HB3 A:LEU141 4.1 12.0 1.0
SD A:MET138 4.1 14.9 1.0
HE1 A:MET222 4.1 14.3 1.0
HE1 A:MET138 4.1 19.8 1.0
CA A:MET138 4.1 9.8 1.0
HD11 A:LEU172 4.2 13.6 1.0
CB A:LEU141 4.2 10.0 1.0
CE A:MET222 4.3 11.9 1.0
H A:MET138 4.3 11.4 1.0
CD1 A:LEU172 4.3 11.3 1.0
CG A:MET138 4.3 11.4 1.0
C3 A:42J501 4.5 15.4 1.0
HD13 A:LEU172 4.5 13.6 1.0
CA A:TYR137 4.5 10.4 1.0
CD1 A:ILE165 4.5 13.5 1.0
HE3 A:MET138 4.5 19.8 1.0
CG1 A:VAL163 4.6 12.9 1.0
HE3 A:MET222 4.6 14.3 1.0
HG11 A:VAL163 4.7 15.5 1.0
HD22 A:LEU141 4.7 13.5 1.0
H1 A:42J501 4.7 18.7 1.0
HD13 A:ILE165 4.7 16.2 1.0
CG A:LEU141 4.8 9.9 1.0
HG22 A:VAL163 4.8 13.7 1.0
HD11 A:ILE165 4.9 16.2 1.0
CB A:MET138 4.9 10.4 1.0
H A:LEU141 4.9 11.6 1.0
HG3 A:MET226 4.9 15.5 0.5

Chlorine binding site 2 out of 6 in 7at9

Go back to Chlorine Binding Sites List in 7at9
Chlorine binding site 2 out of 6 in the Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl501

b:16.2
occ:1.00
 CL A:42J501 0.0 16.2 1.0
C5 A:42J501 1.7 14.5 1.0
C4 A:42J501 2.7 15.6 1.0
C6 A:42J501 2.7 13.4 1.0
H1 A:42J501 2.8 18.7 1.0
HB2 A:TYR137 2.9 13.3 1.0
HA A:ILE134 3.0 13.6 1.0
HG3 A:MET226 3.1 15.5 0.5
HE2 A:MET138 3.1 19.8 1.0
HG2 A:MET138 3.2 13.7 1.0
CL1 A:42J501 3.2 15.6 1.0
HG3 A:MET226 3.3 18.1 0.5
HG23 A:ILE134 3.4 14.5 1.0
HE2 A:MET226 3.4 19.7 0.5
HB3 A:TYR137 3.6 13.3 1.0
CB A:TYR137 3.7 11.1 1.0
HG12 A:ILE134 3.7 17.2 1.0
HD2 A:TYR137 3.9 14.7 1.0
CA A:ILE134 3.9 11.3 1.0
O A:ILE134 4.0 10.6 1.0
H A:MET138 4.0 11.4 1.0
CE A:MET138 4.0 16.5 1.0
C3 A:42J501 4.0 15.4 1.0
C7 A:42J501 4.0 13.0 1.0
CG A:MET226 4.0 12.9 0.5
HE3 A:MET138 4.1 19.8 1.0
HD13 A:LEU129 4.1 49.9 1.0
CG A:MET138 4.1 11.4 1.0
CG A:MET226 4.2 15.0 0.5
CG2 A:ILE134 4.2 12.1 1.0
CE A:MET226 4.3 16.4 0.5
N A:MET138 4.3 9.5 1.0
CB A:ILE134 4.4 12.3 1.0
HB3 A:MET226 4.4 14.5 0.5
C A:ILE134 4.4 10.5 1.0
SD A:MET226 4.5 15.9 0.5
HG3 A:MET138 4.5 13.7 1.0
HB3 A:MET226 4.5 13.8 0.5
CG1 A:ILE134 4.5 14.3 1.0
C2 A:42J501 4.5 13.3 1.0
CD2 A:TYR137 4.6 12.3 1.0
HG21 A:ILE134 4.6 14.5 1.0
CG A:TYR137 4.6 10.8 1.0
C A:TYR137 4.6 9.6 1.0
CA A:TYR137 4.6 10.4 1.0
O A:ASP133 4.6 12.2 1.0
HG2 A:MET226 4.6 15.5 0.5
H A:TYR137 4.7 12.1 1.0
HE1 A:MET138 4.7 19.8 1.0
HD12 A:ILE165 4.7 16.2 1.0
HD21 A:LEU129 4.7 49.9 1.0
H2 A:42J501 4.7 18.5 1.0
H3 A:42J501 4.8 15.6 1.0
CB A:MET226 4.8 12.1 0.5
SD A:MET138 4.8 14.9 1.0
HG2 A:MET226 4.8 18.1 0.5
SD A:MET226 4.8 19.4 0.5
HE3 A:MET226 4.8 19.7 0.5
CB A:MET226 4.8 11.5 0.5
HB2 A:MET226 4.8 14.5 0.5
HE1 A:MET226 4.8 19.7 0.5
HA A:MET138 4.8 11.7 1.0
HG13 A:ILE134 4.9 17.2 1.0
HG22 A:ILE134 4.9 14.5 1.0
HD12 A:LEU129 4.9 49.9 1.0
CD1 A:LEU129 4.9 41.5 1.0
N A:ILE134 4.9 11.9 1.0
HD13 A:ILE165 5.0 16.2 1.0

Chlorine binding site 3 out of 6 in 7at9

Go back to Chlorine Binding Sites List in 7at9
Chlorine binding site 3 out of 6 in the Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl502

b:18.4
occ:1.00
 HH12 A:ARG156 2.4 13.3 1.0
H A:ASN190 2.4 15.4 1.0
HD1 A:TYR189 2.8 14.3 1.0
NH1 A:ARG156 3.2 11.1 1.0
N A:ASN190 3.2 12.8 1.0
HA A:TYR189 3.3 14.0 1.0
HB2 A:ASN190 3.3 19.1 1.0
HH22 A:ARG156 3.3 13.5 1.0
O A:HOH868 3.3 20.2 1.0
HB3 A:TYR189 3.4 14.8 1.0
HG3 A:GLU181 3.4 14.1 0.5
HB3 A:ASN190 3.4 19.1 1.0
CB A:ASN190 3.7 15.9 1.0
HH11 A:ARG156 3.7 13.3 1.0
CD1 A:TYR189 3.7 11.9 1.0
HG2 A:GLU181 3.7 16.9 0.5
O A:HOH811 3.8 32.1 1.0
CA A:TYR189 3.9 11.7 1.0
NH2 A:ARG156 4.0 11.2 1.0
CB A:TYR189 4.0 12.3 1.0
CZ A:ARG156 4.0 9.4 1.0
C A:TYR189 4.1 12.1 1.0
CA A:ASN190 4.1 12.4 1.0
OE1 A:GLU181 4.1 18.7 0.5
CG A:GLU181 4.3 11.8 0.5
CG A:TYR189 4.4 11.5 1.0
HG2 A:GLU181 4.6 14.1 0.5
HH12 A:ARG81 4.6 18.9 1.0
CG A:GLU181 4.6 14.0 0.5
O A:ASN190 4.7 12.4 1.0
HE1 A:TYR189 4.7 14.6 1.0
CE1 A:TYR189 4.7 12.2 1.0
HH21 A:ARG156 4.8 13.5 1.0
OE1 A:GLU181 4.8 13.0 0.5
HH A:TYR210 4.8 12.9 1.0
HA A:ASN190 4.8 14.9 1.0
HB2 A:TYR189 4.9 14.8 1.0
CD A:GLU181 4.9 15.2 0.5
O A:HOH900 4.9 40.0 1.0
C A:ASN190 4.9 12.1 1.0
HB2 A:GLU181 4.9 13.9 0.5
CD A:GLU181 4.9 12.3 0.5
OH A:TYR210 5.0 10.8 1.0
HD22 A:ASN190 5.0 28.2 1.0

Chlorine binding site 4 out of 6 in 7at9

Go back to Chlorine Binding Sites List in 7at9
Chlorine binding site 4 out of 6 in the Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl503

b:19.2
occ:1.00
 HH22 A:ARG230 2.5 14.7 1.0
HH12 A:ARG230 2.6 16.0 1.0
O A:HOH854 2.9 30.9 1.0
O A:HOH860 3.0 41.4 1.0
O A:HOH737 3.1 21.2 1.0
HE1 A:PHE285 3.1 18.5 1.0
HG21 A:VAL249 3.2 17.1 1.0
NH2 A:ARG230 3.2 12.2 1.0
H12 A:EDO510 3.3 43.5 1.0
NH1 A:ARG230 3.3 13.4 1.0
HG23 A:VAL249 3.6 17.1 1.0
CG2 A:VAL249 3.7 14.3 1.0
HZ A:PHE285 3.7 19.5 1.0
CZ A:ARG230 3.7 11.5 1.0
HG22 A:VAL249 3.8 17.1 1.0
HH21 A:ARG230 3.9 14.7 1.0
CE1 A:PHE285 3.9 15.4 1.0
HH11 A:ARG230 4.0 16.0 1.0
CZ A:PHE285 4.2 16.2 1.0
HB3 A:LYS248 4.4 22.2 1.0
C1 A:EDO510 4.4 36.2 1.0
HB2 A:LYS248 4.6 22.2 1.0
H22 A:EDO510 4.8 42.6 1.0
HO1 A:EDO510 4.9 43.7 1.0
H11 A:EDO510 4.9 43.5 1.0
O A:HOH722 4.9 19.1 0.5
O A:HOH958 4.9 40.9 1.0
CB A:LYS248 5.0 18.5 1.0

Chlorine binding site 5 out of 6 in 7at9

Go back to Chlorine Binding Sites List in 7at9
Chlorine binding site 5 out of 6 in the Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl512

b:25.8
occ:0.49
 CL1 A:42J512 0.0 25.8 0.5
HAGA A:4B0511 1.7 15.2 0.2
C6 A:42J512 1.7 20.1 0.5
HE1 A:MET164 1.9 19.4 0.7
SD A:MET164 2.1 15.3 0.7
CE A:MET164 2.3 16.2 0.7
CAG A:4B0511 2.5 12.6 0.2
HOAA A:4B0511 2.6 15.4 0.2
C7 A:42J512 2.7 17.6 0.5
HAF A:4B0511 2.7 15.2 0.2
C5 A:42J512 2.7 19.9 0.5
H3 A:42J512 2.8 21.1 0.5
BRAD A:4B0511 2.8 33.9 0.3
HE3 A:MET164 2.9 19.4 0.7
CAF A:4B0511 2.9 12.7 0.2
HG2 A:MET164 3.0 16.7 0.3
HE2 A:MET164 3.1 19.4 0.7
OAA A:4B0511 3.2 12.8 0.2
CL A:42J512 3.2 22.6 0.5
HAG A:4B0511 3.2 15.2 0.2
BRAE A:4B0511 3.2 17.5 0.2
HD22 A:ASN119 3.2 26.8 1.0
CAM A:4B0511 3.3 19.0 0.3
CAN A:4B0511 3.3 16.0 0.2
CAP A:4B0511 3.3 14.5 0.2
CAH A:4B0511 3.3 13.1 0.2
ND2 A:ASN119 3.4 22.3 1.0
NAQ A:4B0511 3.4 14.1 0.2
O A:HOH867 3.5 15.5 0.4
HD21 A:ASN119 3.5 26.8 1.0
HAHA A:4B0511 3.5 15.8 0.2
CAO A:4B0511 3.6 13.8 0.3
NAI A:4B0511 3.6 16.1 0.3
O A:HOH621 3.7 50.6 1.0
O A:HOH899 3.7 45.0 1.0
CG A:MET164 3.8 13.9 0.7
CG A:MET164 3.8 13.9 0.3
HAFA A:4B0511 3.9 15.2 0.2
CG A:ASN119 3.9 19.7 1.0
HD13 A:ILE175 3.9 13.7 1.0
HD12 A:ILE175 3.9 13.7 1.0
C2 A:42J512 4.0 20.0 0.5
C4 A:42J512 4.0 19.7 0.5
HG2 A:MET164 4.0 16.7 0.7
HB2 A:ASN119 4.1 22.5 1.0
HG3 A:MET164 4.1 16.7 0.7
CAK A:4B0511 4.1 14.3 0.3
CAL A:4B0511 4.2 20.1 0.2
SD A:MET164 4.2 15.3 0.3
HAH A:4B0511 4.2 15.8 0.2
O A:HIS161 4.3 16.1 1.0
CAO A:4B0511 4.3 13.7 0.2
HG3 A:MET164 4.3 16.7 0.3
NAJ A:4B0511 4.3 13.6 0.2
HB3 A:ASN119 4.3 22.5 1.0
O A:HOH961 4.3 40.2 1.0
CB A:ASN119 4.3 18.7 1.0
CD1 A:ILE175 4.4 11.4 1.0
C3 A:42J512 4.5 20.5 0.5
OD1 A:ASN119 4.6 18.5 1.0
O A:HOH867 4.6 25.7 0.6
NAJ A:4B0511 4.6 17.5 0.3
CAP A:4B0511 4.6 11.7 0.3
HA A:MET164 4.7 13.6 0.7
HA A:MET164 4.7 13.0 0.3
H1 A:42J512 4.7 23.6 0.5
NAI A:4B0511 4.7 14.0 0.2
BRAB A:4B0511 4.8 12.9 0.3
HB3 A:MET164 4.8 15.0 0.3
HD11 A:ILE175 4.8 13.7 1.0
CB A:MET164 4.9 12.5 0.3
CB A:MET164 4.9 12.6 0.7
HB3 A:MET164 5.0 15.2 0.7
CAK A:4B0511 5.0 17.4 0.2
CAM A:4B0511 5.0 12.2 0.2

Chlorine binding site 6 out of 6 in 7at9

Go back to Chlorine Binding Sites List in 7at9
Chlorine binding site 6 out of 6 in the Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Structure of Protein Kinase CK2 Catalytic Subunit (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor MB002 and the Alphad-Pocket Ligand 3,4-Dichlorophenethylamine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl512

b:22.6
occ:0.49
 CL A:42J512 0.0 22.6 0.5
HAHA A:4B0511 0.9 15.8 0.2
BRAD A:4B0511 1.6 33.9 0.3
CAH A:4B0511 1.7 13.1 0.2
C5 A:42J512 1.7 19.9 0.5
BRAE A:4B0511 1.9 17.5 0.2
HAGA A:4B0511 2.2 15.2 0.2
NAQ A:4B0511 2.4 14.1 0.2
CAG A:4B0511 2.4 12.6 0.2
HAH A:4B0511 2.4 15.8 0.2
CAN A:4B0511 2.6 16.0 0.2
CAP A:4B0511 2.7 14.5 0.2
C4 A:42J512 2.7 19.7 0.5
C6 A:42J512 2.7 20.1 0.5
HB3 A:LEU46 2.7 19.1 1.0
HAG A:4B0511 2.8 15.2 0.2
H1 A:42J512 2.8 23.6 0.5
NAI A:4B0511 2.8 16.1 0.3
CAM A:4B0511 2.8 19.0 0.3
O A:HOH899 3.0 45.0 1.0
CAO A:4B0511 3.1 13.8 0.3
CL1 A:42J512 3.2 25.8 0.5
HD13 A:LEU46 3.4 21.8 1.0
O A:HOH802 3.6 42.4 1.0
CB A:LEU46 3.7 16.0 1.0
NAJ A:4B0511 3.7 13.6 0.2
O A:HOH961 3.7 40.2 1.0
CAF A:4B0511 3.7 12.7 0.2
O A:LEU46 3.8 22.5 1.0
HAF A:4B0511 3.9 15.2 0.2
HB2 A:LEU46 3.9 19.1 1.0
C3 A:42J512 4.0 20.5 0.5
HD21 A:LEU46 4.0 21.8 1.0
C7 A:42J512 4.0 17.6 0.5
CAL A:4B0511 4.0 20.1 0.2
CAO A:4B0511 4.0 13.7 0.2
NAJ A:4B0511 4.1 17.5 0.3
CAK A:4B0511 4.1 14.3 0.3
HAFA A:4B0511 4.2 15.2 0.2
CD1 A:LEU46 4.3 18.2 1.0
O A:HOH813 4.4 47.1 1.0
C A:LEU46 4.4 19.1 1.0
CG A:LEU46 4.4 15.6 1.0
NAI A:4B0511 4.5 14.0 0.2
HG22 A:VAL54 4.5 16.9 0.3
CAP A:4B0511 4.5 11.7 0.3
C2 A:42J512 4.5 20.0 0.5
HD11 A:LEU46 4.6 21.8 1.0
CA A:LEU46 4.6 16.3 1.0
HOAA A:4B0511 4.6 15.4 0.2
HA A:LEU46 4.7 19.6 1.0
CD2 A:LEU46 4.7 18.1 1.0
HD22 A:ASN119 4.7 26.8 1.0
OAA A:4B0511 4.7 12.8 0.2
H2 A:42J512 4.7 24.6 0.5
H3 A:42J512 4.7 21.1 0.5
SD A:MET164 4.8 15.3 0.7
BRAB A:4B0511 4.8 12.9 0.3
NAQ A:4B0511 4.9 15.0 0.3
BRAC A:4B0511 5.0 27.6 0.2

Reference:

D.Lindenblatt, V.Applegate, A.Nickelsen, M.Klussmann, I.Neundorf, C.Gotz, J.Jose, K.Niefind. Molecular Plasticity of Crystalline CK2 Alpha ' Leads to KN2, A Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity J.Med.Chem. 2021.
ISSN: ISSN 0022-2623
DOI: 10.1021/ACS.JMEDCHEM.1C00063
Page generated: Mon Jul 29 18:42:08 2024

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