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Chlorine in PDB 7av0: LTA4 Hydrolase in Complex with Compound R(13)Enzymatic activity of LTA4 Hydrolase in Complex with Compound R(13)
All present enzymatic activity of LTA4 Hydrolase in Complex with Compound R(13):
3.3.2.6; Protein crystallography data
The structure of LTA4 Hydrolase in Complex with Compound R(13), PDB code: 7av0
was solved by
H.Srinivas,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7av0:
The structure of LTA4 Hydrolase in Complex with Compound R(13) also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the LTA4 Hydrolase in Complex with Compound R(13)
(pdb code 7av0). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the LTA4 Hydrolase in Complex with Compound R(13), PDB code: 7av0: Chlorine binding site 1 out of 1 in 7av0Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the LTA4 Hydrolase in Complex with Compound R(13)
![]() Mono view ![]() Stereo pair view
Reference:
C.Markert,
G.Thoma,
H.Srinivas,
B.Bollbuck,
R.M.Luond,
W.Miltz,
R.Wal̈Chli,
R.Wolf,
J.Hinrichs,
C.Bergsdorf,
K.Azzaoui,
C.A.Penno,
K.Klein,
N.Wack,
P.Jag̈Er,
F.Hasler,
C.Beerli,
P.Loetscher,
J.Dawson,
G.Wieczorek,
S.Numao,
A.Littlewood-Evans,
T.A.Rohn.
Discovery of LYS006, A Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase. J.Med.Chem. 2021.
Page generated: Wed Mar 3 12:57:16 2021
ISSN: ISSN 0022-2623 |
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