Chlorine in PDB 7b1t: Crystal Structure of BRD4(1) in Complex with the Inhibitor MPM6

The structure of Crystal Structure of BRD4(1) in Complex with the Inhibitor MPM6, PDB code: 7b1t was solved by M.Huegle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.05 / 1.92
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	37.31, 44.43, 76.8, 90, 90, 90
R / Rfree (%)	16.2 / 18.9

The binding sites of Chlorine atom in the Crystal Structure of BRD4(1) in Complex with the Inhibitor MPM6 (pdb code 7b1t). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of BRD4(1) in Complex with the Inhibitor MPM6, PDB code: 7b1t:

Chlorine binding site 1 out of 1 in the Crystal Structure of BRD4(1) in Complex with the Inhibitor MPM6


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of BRD4(1) in Complex with the Inhibitor MPM6 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:9.2 occ:1.00 CL A:SOK201 0.0 9.2 1.0 C11 A:SOK201 1.7 5.6 1.0 C12 A:SOK201 2.7 4.5 1.0 C10 A:SOK201 2.7 5.0 1.0 C9 A:SOK201 3.1 5.3 1.0 C7 A:SOK201 3.4 5.0 1.0 C8 A:SOK201 3.5 8.5 1.0 C6 A:SOK201 3.8 7.7 1.0 O A:DMS202 3.9 10.2 0.8 CZ3 A:TRP81 3.9 6.8 1.0 CB A:PRO82 3.9 6.7 1.0 C13 A:SOK201 4.0 8.4 1.0 C15 A:SOK201 4.0 6.1 1.0 C1 A:DMS202 4.1 8.7 0.8 CH2 A:TRP81 4.2 7.7 1.0 N A:SOK201 4.2 5.5 1.0 CG A:PRO82 4.3 7.3 1.0 C14 A:SOK201 4.5 10.5 1.0 CA A:PRO82 4.6 4.5 1.0 CD2 A:LEU92 4.6 8.0 1.0 S A:DMS202 4.6 11.3 0.8 C2 A:SOK201 4.7 6.1 1.0 CD1 A:ILE146 4.7 7.9 1.0 CE3 A:TRP81 4.8 7.9 1.0 CD1 A:LEU92 4.9 9.6 1.0 C A:SOK201 5.0 4.9 1.0

M.Pervaiz, M.Huegle. N/A N/A.