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Chlorine in PDB 7bjh: Crystal Structure of CHK1-10PT-Mutant Complex with Compound 8Enzymatic activity of Crystal Structure of CHK1-10PT-Mutant Complex with Compound 8
All present enzymatic activity of Crystal Structure of CHK1-10PT-Mutant Complex with Compound 8:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of CHK1-10PT-Mutant Complex with Compound 8, PDB code: 7bjh
was solved by
P.Dokurno,
A.E.Surgenor,
D.S.Williamson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of CHK1-10PT-Mutant Complex with Compound 8
(pdb code 7bjh). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of CHK1-10PT-Mutant Complex with Compound 8, PDB code: 7bjh: Chlorine binding site 1 out of 1 in 7bjhGo back to Chlorine Binding Sites List in 7bjh
Chlorine binding site 1 out
of 1 in the Crystal Structure of CHK1-10PT-Mutant Complex with Compound 8
Mono view Stereo pair view
Reference:
D.S.Williamson,
G.P.Smith,
G.K.Mikkelsen,
T.Jensen,
P.Acheson-Dossang,
L.Badolo,
S.T.Bedford,
V.Chell,
I.J.Chen,
P.Dokurno,
M.Hentzer,
S.Newland,
S.C.Ray,
T.Shaw,
A.E.Surgenor,
L.Terry,
Y.Wang,
K.V.Christensen.
Design and Synthesis of Pyrrolo[2,3- D ]Pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using A Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate. J.Med.Chem. 2021.
Page generated: Sat Jul 10 12:34:12 2021
ISSN: ISSN 0022-2623 PubMed: 34184879 DOI: 10.1021/ACS.JMEDCHEM.1C00720 |
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