Atomistry » Chlorine » PDB 7bmt-7c15 » 7bq0
Atomistry »
  Chlorine »
    PDB 7bmt-7c15 »
      7bq0 »

Chlorine in PDB 7bq0: X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization

Enzymatic activity of X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization

All present enzymatic activity of X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization:
2.3.1.48;

Protein crystallography data

The structure of X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization, PDB code: 7bq0 was solved by S.Kamata, R.Ishikawa, M.Akahane, T.Oyama, I.Ishii, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.74 / 1.77
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 60.591, 100.618, 61.990, 90.00, 101.63, 90.00
R / Rfree (%) 19 / 21.7

Chlorine Binding Sites:

The binding sites of Chlorine atom in the X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization (pdb code 7bq0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization, PDB code: 7bq0:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 7bq0

Go back to Chlorine Binding Sites List in 7bq0
Chlorine binding site 1 out of 4 in the X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl501

b:40.3
occ:1.00
 CL1 A:F5A501 0.0 40.3 1.0
C22 A:F5A501 1.8 36.8 1.0
C21 A:F5A501 2.7 31.6 1.0
C20 A:F5A501 2.7 37.3 1.0
H23 A:F5A501 2.8 38.0 1.0
H22 A:F5A501 2.8 44.8 1.0
CB A:LYS448 3.2 30.8 1.0
CA A:LYS448 3.4 36.1 1.0
CG A:LYS448 3.5 36.8 1.0
CB A:LEU456 3.8 39.4 1.0
C19 A:F5A501 4.0 34.8 1.0
C18 A:F5A501 4.0 33.0 1.0
CD A:LYS448 4.1 37.4 1.0
N A:LYS448 4.1 28.6 1.0
N A:LEU456 4.4 29.5 1.0
C17 A:F5A501 4.5 34.7 1.0
CD2 A:LEU456 4.6 36.5 1.0
C A:LYS448 4.7 38.3 1.0
CG A:LEU456 4.7 34.1 1.0
O A:ALA454 4.7 40.8 1.0
CA A:LEU456 4.7 33.6 1.0
H18 A:F5A501 4.7 39.6 1.0
H19 A:F5A501 4.7 41.8 1.0
O A:LYS448 4.8 32.9 1.0
O A:VAL444 4.9 31.0 1.0
C A:ALA455 4.9 36.9 1.0
C A:ILE447 4.9 31.1 1.0

Chlorine binding site 2 out of 4 in 7bq0

Go back to Chlorine Binding Sites List in 7bq0
Chlorine binding site 2 out of 4 in the X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl502

b:57.1
occ:1.00
 CL1 A:F5A502 0.0 57.1 1.0
C22 A:F5A502 1.8 49.8 1.0
C21 A:F5A502 2.7 42.1 1.0
C20 A:F5A502 2.7 41.5 1.0
H23 A:F5A502 2.7 50.5 1.0
H22 A:F5A502 2.9 49.7 1.0
CD1 A:LEU247 3.5 29.0 1.0
O A:HOH675 3.7 33.6 1.0
C19 A:F5A502 4.0 36.5 1.0
C18 A:F5A502 4.0 38.8 1.0
CD1 A:ILE241 4.1 32.6 1.0
CD1 A:ILE339 4.3 33.4 1.0
CG1 A:ILE272 4.4 28.5 1.0
C17 A:F5A502 4.5 40.4 1.0
CG2 A:ILE272 4.5 29.0 1.0
CA A:ILE272 4.6 26.4 1.0
H19 A:F5A502 4.7 43.8 1.0
CB A:ILE272 4.7 26.4 1.0
H18 A:F5A502 4.7 46.6 1.0
CG2 A:ILE241 5.0 29.4 1.0
CG A:LEU247 5.0 27.9 1.0

Chlorine binding site 3 out of 4 in 7bq0

Go back to Chlorine Binding Sites List in 7bq0
Chlorine binding site 3 out of 4 in the X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl501

b:42.0
occ:1.00
 CL1 C:F5A501 0.0 42.0 1.0
C22 C:F5A501 1.8 36.0 1.0
C21 C:F5A501 2.7 34.4 1.0
C20 C:F5A501 2.8 29.9 1.0
H23 C:F5A501 2.8 41.3 1.0
H22 C:F5A501 2.9 35.9 1.0
CG C:LYS448 3.3 39.7 1.0
CB C:LYS448 3.3 39.6 1.0
CA C:LYS448 3.5 34.1 1.0
CB C:LEU456 3.7 38.5 1.0
C19 C:F5A501 4.0 37.1 1.0
C18 C:F5A501 4.1 32.7 1.0
N C:LYS448 4.1 31.2 1.0
CD C:LYS448 4.2 39.6 1.0
CD2 C:LEU456 4.3 32.9 1.0
N C:LEU456 4.3 35.1 1.0
C17 C:F5A501 4.5 30.6 1.0
CG C:LEU456 4.6 31.4 1.0
O C:ALA454 4.6 45.9 1.0
CA C:LEU456 4.6 35.2 1.0
CE C:LYS448 4.7 43.5 1.0
C C:LYS448 4.7 36.4 1.0
H19 C:F5A501 4.7 44.5 1.0
H18 C:F5A501 4.8 39.3 1.0
O C:VAL444 4.9 32.2 1.0
C C:ILE447 4.9 34.4 1.0
C C:ALA455 4.9 39.4 1.0
O C:LYS448 4.9 40.6 1.0
CD1 C:LEU456 5.0 31.0 1.0

Chlorine binding site 4 out of 4 in 7bq0

Go back to Chlorine Binding Sites List in 7bq0
Chlorine binding site 4 out of 4 in the X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of X-Ray Structure of Human Pparalpha Ligand Binding Domain-Fenofibric Acid-SRC1 Coactivator Peptide Co-Crystals Obtained By Delipidation and Co-Crystallization within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl502

b:70.4
occ:1.00
 CL1 C:F5A502 0.0 70.4 1.0
C22 C:F5A502 1.8 52.6 1.0
C21 C:F5A502 2.7 50.0 1.0
C20 C:F5A502 2.7 49.8 1.0
H23 C:F5A502 2.8 60.0 1.0
H22 C:F5A502 2.8 59.8 1.0
CD1 C:LEU247 3.6 26.5 1.0
C19 C:F5A502 4.0 47.8 1.0
C18 C:F5A502 4.0 44.5 1.0
CD1 C:ILE241 4.3 30.6 1.0
CD1 C:ILE339 4.3 34.3 1.0
CG1 C:ILE272 4.3 27.1 1.0
CG2 C:ILE272 4.4 27.0 1.0
CA C:ILE272 4.5 26.1 1.0
C17 C:F5A502 4.5 48.6 1.0
CB C:ILE272 4.6 27.6 1.0
H19 C:F5A502 4.7 57.4 1.0
H18 C:F5A502 4.8 53.4 1.0
O C:ILE272 5.0 26.0 1.0

Reference:

S.Kamata, T.Oyama, K.Saito, A.Honda, Y.Yamamoto, K.Suda, R.Ishikawa, T.Itoh, Y.Watanabe, T.Shibata, K.Uchida, M.Suematsu, I.Ishii. Ppar Alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates. Iscience V. 23 01727 2020.
ISSN: ESSN 2589-0042
PubMed: 33205029
DOI: 10.1016/J.ISCI.2020.101727
Page generated: Mon Jul 29 19:19:28 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy