Chlorine in PDB 7c19: Crystal Structure of A Dinucleotide-Binding Protein (Y224A/Y246A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho- Guanosine (Form II)

The structure of Crystal Structure of A Dinucleotide-Binding Protein (Y224A/Y246A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho- Guanosine (Form II), PDB code: 7c19 was solved by S.P.Kanaujia, M.Chandravanshi, R.Samanta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	57.25 / 1.77
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	66.31, 58.84, 103.58, 90, 93.1, 90
R / Rfree (%)	18.1 / 22.2

The binding sites of Chlorine atom in the Crystal Structure of A Dinucleotide-Binding Protein (Y224A/Y246A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho- Guanosine (Form II) (pdb code 7c19). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of A Dinucleotide-Binding Protein (Y224A/Y246A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho- Guanosine (Form II), PDB code: 7c19:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of A Dinucleotide-Binding Protein (Y224A/Y246A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho- Guanosine (Form II)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of A Dinucleotide-Binding Protein (Y224A/Y246A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho- Guanosine (Form II) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:42.9 occ:1.00 O A:HOH700 2.6 22.2 1.0 O A:HOH761 3.0 22.6 1.0 O A:PRO268 3.1 13.6 1.0 NE2 A:GLN267 3.5 19.3 1.0 C A:PRO268 3.9 13.9 1.0 CG A:GLN267 3.9 20.5 1.0 O A:HOH891 3.9 36.6 1.0 O A:GLN267 3.9 15.7 1.0 CD A:GLN267 3.9 20.2 1.0 CA A:GLY269 4.1 12.4 1.0 CE2 A:TYR270 4.2 13.3 1.0 OD1 A:ASN183 4.2 14.0 1.0 N A:GLY269 4.2 13.2 1.0 N A:ARG263 4.3 19.8 1.0 CB A:GLN267 4.3 19.7 1.0 CD2 A:TYR270 4.3 12.8 1.0 CA A:GLY262 4.4 16.4 1.0 C A:GLN267 4.4 16.9 1.0 O A:HOH816 4.5 24.7 1.0 C A:GLY269 4.6 11.8 1.0 N A:TYR270 4.6 11.7 1.0 CZ A:TYR270 4.7 13.4 1.0 OE1 A:GLN267 4.8 18.7 1.0 C A:GLY262 4.9 17.6 1.0 N A:PRO268 4.9 15.8 1.0 CA A:GLN267 5.0 18.6 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of A Dinucleotide-Binding Protein (Y224A/Y246A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho- Guanosine (Form II)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of A Dinucleotide-Binding Protein (Y224A/Y246A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho- Guanosine (Form II) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl501 b:64.1 occ:1.00 O B:HOH827 4.0 24.2 1.0 N B:GLY26 4.1 22.8 1.0 CA B:GLY25 4.3 25.1 1.0 C B:GLY25 4.7 24.0 1.0 CA B:GLY26 5.0 21.1 1.0

M.Chandravanshi, R.Samanta, S.P.Kanaujia. Structural and Thermodynamic Insights Into the Novel Dinucleotide-Binding Protein of Abc Transporter Unveils Its Moonlighting Function. Febs J. 2021.
ISSN: ISSN 1742-464X
PubMed: 33599038
DOI: 10.1111/FEBS.15774