Chlorine in PDB 7c3q: Human Mdmx Protein in Complex with NUTLIN3A

The structure of Human Mdmx Protein in Complex with NUTLIN3A, PDB code: 7c3q was solved by Z.D.Su, X.Y.Cheng, B.L.Zhang, Z.K.Kuang, J.Yang, Z.C.Li, J.P.Yu, Z.T.Zhao, C.Z.Cao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.43 / 1.80
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	47.727, 47.727, 92.321, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / 24.1

The binding sites of Chlorine atom in the Human Mdmx Protein in Complex with NUTLIN3A (pdb code 7c3q). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Mdmx Protein in Complex with NUTLIN3A, PDB code: 7c3q:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Human Mdmx Protein in Complex with NUTLIN3A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Mdmx Protein in Complex with NUTLIN3A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl202 b:29.1 occ:1.00 CL1 A:NUT202 0.0 29.1 1.0 C22 A:NUT202 1.7 26.3 1.0 C21 A:NUT202 2.7 25.9 1.0 C23 A:NUT202 2.7 26.3 1.0 H25 A:NUT202 2.8 25.9 1.0 H24 A:NUT202 2.8 26.3 1.0 HD21 A:LEU97 2.9 33.2 1.0 HB3 A:LEU55 3.0 24.1 1.0 HD22 A:LEU97 3.0 33.2 1.0 HZ A:PHE89 3.0 33.8 1.0 HD12 A:ILE59 3.1 25.0 1.0 HD11 A:ILE59 3.2 25.0 1.0 HD13 A:LEU97 3.4 35.0 1.0 CD2 A:LEU97 3.4 33.2 1.0 HD12 A:LEU97 3.5 35.0 1.0 CD1 A:ILE59 3.6 25.0 1.0 HD13 A:LEU55 3.6 25.2 1.0 CD1 A:LEU97 3.8 35.0 1.0 CZ A:PHE89 3.9 33.8 1.0 CB A:LEU55 3.9 24.1 1.0 C20 A:NUT202 4.0 25.3 1.0 C24 A:NUT202 4.0 27.3 1.0 HD13 A:ILE59 4.0 25.0 1.0 HD21 A:LEU55 4.1 27.9 1.0 HB2 A:LEU55 4.1 24.1 1.0 HD23 A:LEU97 4.2 33.2 1.0 CG A:LEU97 4.2 34.5 1.0 HE1 A:PHE89 4.3 34.5 1.0 HD22 A:LEU80 4.4 24.4 1.0 CD1 A:LEU55 4.4 25.2 1.0 C19 A:NUT202 4.5 24.8 1.0 CE1 A:PHE89 4.5 34.5 1.0 C A:LEU55 4.6 23.1 1.0 HE1 A:MET52 4.6 32.9 1.0 CG A:LEU55 4.6 25.1 1.0 HE3 A:MET52 4.6 32.9 1.0 HA2 A:GLY56 4.7 27.6 1.0 O A:LEU55 4.7 22.8 1.0 HG13 A:ILE59 4.7 22.1 1.0 H26 A:NUT202 4.7 25.3 1.0 HD11 A:LEU55 4.7 25.2 1.0 H23 A:NUT202 4.7 27.3 1.0 HD11 A:LEU97 4.7 35.0 1.0 CG1 A:ILE59 4.8 22.1 1.0 CD2 A:LEU55 4.8 27.9 1.0 HE2 A:PHE89 4.8 33.9 1.0 N A:GLY56 4.8 25.8 1.0 CE2 A:PHE89 4.8 33.9 1.0 HD12 A:LEU80 4.8 28.8 1.0 HB2 A:LEU97 4.9 27.9 1.0 CA A:LEU55 4.9 23.6 1.0 HG A:LEU97 4.9 34.5 1.0

Chlorine binding site 2 out of 2 in the Human Mdmx Protein in Complex with NUTLIN3A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Mdmx Protein in Complex with NUTLIN3A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl202 b:34.2 occ:1.00 CL A:NUT202 0.0 34.2 1.0 C15 A:NUT202 1.7 31.3 1.0 C16 A:NUT202 2.7 28.3 1.0 C14 A:NUT202 2.7 34.5 1.0 H31 A:NUT202 2.8 28.3 1.0 H32 A:NUT202 2.8 34.5 1.0 HD23 A:LEU97 2.9 33.2 1.0 HB2 A:PRO94 3.0 37.1 1.0 HE2 A:TYR98 3.3 30.4 1.0 HE2 A:MET52 3.4 32.9 1.0 HB3 A:PRO94 3.6 37.1 1.0 CB A:PRO94 3.7 37.1 1.0 HG3 A:PRO94 3.7 34.2 1.0 CE2 A:TYR98 3.8 30.4 1.0 CD2 A:LEU97 3.8 33.2 1.0 HD22 A:LEU97 3.9 33.2 1.0 C17 A:NUT202 4.0 26.8 1.0 C13 A:NUT202 4.0 28.4 1.0 HE1 A:MET52 4.0 32.9 1.0 HG A:LEU97 4.1 34.5 1.0 CG A:PRO94 4.1 34.2 1.0 HG2 A:PRO94 4.1 34.2 1.0 CE A:MET52 4.2 32.9 1.0 HB3 A:LEU97 4.2 27.9 1.0 HD2 A:TYR98 4.3 27.3 1.0 CD2 A:TYR98 4.3 27.3 1.0 CZ A:TYR98 4.4 29.8 1.0 CG A:LEU97 4.4 34.5 1.0 C12 A:NUT202 4.5 28.8 1.0 HD21 A:LEU97 4.5 33.2 1.0 OH A:TYR98 4.5 32.9 1.0 HE3 A:MET52 4.7 32.9 1.0 H30 A:NUT202 4.7 26.8 1.0 H33 A:NUT202 4.7 28.4 1.0 CB A:LEU97 4.8 27.9 1.0 O A:PRO94 4.9 30.3 1.0

Z.D.Su, X.Y.Cheng, B.L.Zhang, Z.K.Kuang, J.Yang, Z.C.Li, J.P.Yu, Z.T.Zhao, C.Z.Cao. Human Mdmx Protein in Complex with NUTLIN3A To Be Published.