Chlorine in PDB 7cnn: Vinorelbine in Complex with Tubulin

The structure of Vinorelbine in Complex with Tubulin, PDB code: 7cnn was solved by Y.X.Wang, C.Y.Wu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.96 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	104.878, 156.129, 183, 90, 90, 90
R / Rfree (%)	19.9 / 22.9

The structure of Vinorelbine in Complex with Tubulin also contains other interesting chemical elements:

Magnesium	(Mg)	5 atoms
Calcium	(Ca)	4 atoms

The binding sites of Chlorine atom in the Vinorelbine in Complex with Tubulin (pdb code 7cnn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Vinorelbine in Complex with Tubulin, PDB code: 7cnn:

Chlorine binding site 1 out of 1 in the Vinorelbine in Complex with Tubulin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Vinorelbine in Complex with Tubulin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl504 b:51.8 occ:1.00 N A:GLY162 3.3 54.9 1.0 N A:LYS163 3.4 54.5 1.0 C A:TYR161 3.4 52.1 1.0 CA A:TYR161 3.5 53.4 1.0 NZ A:LYS164 3.9 59.7 1.0 CG A:LYS164 4.0 50.9 1.0 CE A:LYS164 4.1 56.5 1.0 O A:TYR161 4.1 51.6 1.0 CA A:GLY162 4.2 56.1 1.0 CA A:LYS163 4.2 59.3 1.0 CB A:LYS163 4.2 58.8 1.0 C A:GLY162 4.3 55.7 1.0 CB A:TYR161 4.3 46.8 1.0 O A:HOH683 4.3 46.0 1.0 N A:LYS164 4.3 50.3 1.0 CD A:LYS164 4.4 52.9 1.0 O A:ASP160 4.6 57.6 1.0 C A:LYS163 4.6 56.7 1.0 N A:TYR161 4.7 56.6 1.0 CG A:LYS163 4.8 63.6 1.0

Y.X.Wang, C.Y.Wu. Vincristinve in Complex with Tubulin To Be Published.