Chlorine in PDB 7cum: Cryo-Em Structure of Human Gaba(B) Receptor Bound to the Antagonist CGP54626

The binding sites of Chlorine atom in the Cryo-Em Structure of Human Gaba(B) Receptor Bound to the Antagonist CGP54626 (pdb code 7cum). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Cryo-Em Structure of Human Gaba(B) Receptor Bound to the Antagonist CGP54626, PDB code: 7cum:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Cryo-Em Structure of Human Gaba(B) Receptor Bound to the Antagonist CGP54626


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of Human Gaba(B) Receptor Bound to the Antagonist CGP54626 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1001 b:43.7 occ:1.00 CL1 A:2BV1001 0.0 43.7 1.0 C6 A:2BV1001 1.8 43.7 1.0 C7 A:2BV1001 2.8 43.7 1.0 C5 A:2BV1001 2.8 43.7 1.0 CL2 A:2BV1001 3.1 43.7 1.0 HD1 A:TRP182 3.4 43.5 1.0 C15 A:2BV1001 3.9 43.7 1.0 C8 A:2BV1001 4.1 43.7 1.0 C4 A:2BV1001 4.1 43.7 1.0 CD1 A:TRP182 4.3 43.5 1.0 HA A:TRP182 4.3 43.5 1.0 O A:GLY181 4.4 47.7 1.0 C3 A:2BV1001 4.6 43.7 1.0 HD2 A:PRO183 4.6 43.9 1.0 C14 A:2BV1001 4.7 43.7 1.0 HB2 A:TRP182 4.9 43.5 1.0

Chlorine binding site 2 out of 2 in the Cryo-Em Structure of Human Gaba(B) Receptor Bound to the Antagonist CGP54626


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Cryo-Em Structure of Human Gaba(B) Receptor Bound to the Antagonist CGP54626 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1001 b:43.7 occ:1.00 CL2 A:2BV1001 0.0 43.7 1.0 C5 A:2BV1001 1.8 43.7 1.0 HD1 A:TRP182 2.4 43.5 1.0 HE1 A:TRP182 2.5 43.5 1.0 C4 A:2BV1001 2.8 43.7 1.0 C6 A:2BV1001 2.8 43.7 1.0 CD1 A:TRP182 2.9 43.5 1.0 NE1 A:TRP182 2.9 43.5 1.0 CL1 A:2BV1001 3.1 43.7 1.0 H A:GLY463 3.9 46.6 1.0 C3 A:2BV1001 4.1 43.7 1.0 C7 A:2BV1001 4.1 43.7 1.0 CG A:TRP182 4.2 43.5 1.0 HD2 A:PRO183 4.2 43.9 1.0 CE2 A:TRP182 4.2 43.5 1.0 HA2 A:GLY463 4.4 46.6 1.0 HA A:TRP182 4.5 43.5 1.0 C8 A:2BV1001 4.6 43.7 1.0 N A:GLY463 4.6 46.6 1.0 CD2 A:TRP182 4.9 43.5 1.0 OE1 A:GLU466 4.9 43.0 1.0

Y.Kim, E.Jeong, J.H.Jeong, Y.Kim, Y.Cho. Structural Basis For Activation of the Heterodimeric Gaba B Receptor. J.Mol.Biol. V. 432 5966 2020.
ISSN: ESSN 1089-8638
PubMed: 33058878
DOI: 10.1016/J.JMB.2020.09.023