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Chlorine in PDB 7cwa: Crystal Structure of PDE8A Catalytic Domain in Complex with ClofarabineEnzymatic activity of Crystal Structure of PDE8A Catalytic Domain in Complex with Clofarabine
All present enzymatic activity of Crystal Structure of PDE8A Catalytic Domain in Complex with Clofarabine:
3.1.4.53; Protein crystallography data
The structure of Crystal Structure of PDE8A Catalytic Domain in Complex with Clofarabine, PDB code: 7cwa
was solved by
Y.Huang,
X.-N.Wu,
Q.Zhou,
Y.Wu,
H.-B.Luo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7cwa:
The structure of Crystal Structure of PDE8A Catalytic Domain in Complex with Clofarabine also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of PDE8A Catalytic Domain in Complex with Clofarabine
(pdb code 7cwa). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of PDE8A Catalytic Domain in Complex with Clofarabine, PDB code: 7cwa: Chlorine binding site 1 out of 1 in 7cwaGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of PDE8A Catalytic Domain in Complex with Clofarabine
![]() Mono view ![]() Stereo pair view
Reference:
Y.Huang,
X.Wu,
Q.Zhou,
H.-B.Luo.
Discovery of Highly Selective and Orally Bioavailable Phosphodiesterase-8A Inhibitors. Structure-Activity Relationship, Crystal Structures, and in Vivo Studies To Be Published.
Page generated: Fri Sep 24 12:51:28 2021
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