Chlorine in PDB 7d4p: Structure of Human TRPC5 in Complex with Clemizole

The structure of Structure of Human TRPC5 in Complex with Clemizole also contains other interesting chemical elements:

Calcium	(Ca)	4 atoms
Zinc	(Zn)	4 atoms

The binding sites of Chlorine atom in the Structure of Human TRPC5 in Complex with Clemizole (pdb code 7d4p). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Structure of Human TRPC5 in Complex with Clemizole, PDB code: 7d4p:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Structure of Human TRPC5 in Complex with Clemizole


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Human TRPC5 in Complex with Clemizole within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl801 b:109.5 occ:1.00 CL A:GX0801 0.0 109.5 1.0 C18 A:GX0801 1.8 105.2 1.0 C17 A:GX0801 2.8 100.4 1.0 C16 A:GX0801 2.8 98.2 1.0 CE2 A:TYR446 3.2 79.2 1.0 CB A:MET442 3.4 86.4 1.0 CD2 A:TYR446 3.5 83.3 1.0 CD2 A:PHE414 3.8 95.4 1.0 SD A:MET442 3.8 87.9 1.0 C15 A:GX0801 4.1 97.5 1.0 C14 A:GX0801 4.1 100.6 1.0 OG A:SER489 4.1 74.0 1.0 CG A:MET442 4.1 85.1 1.0 ND2 A:ASN443 4.1 98.9 1.0 CE2 A:PHE414 4.3 95.1 1.0 CG A:PHE414 4.4 94.0 1.0 C A:MET442 4.4 81.3 1.0 CA A:MET442 4.5 81.0 1.0 CZ A:TYR446 4.5 83.6 1.0 N A:ASN443 4.5 86.1 1.0 CB A:PHE414 4.5 90.1 1.0 C9 A:GX0801 4.6 100.6 1.0 CG A:TYR446 4.8 83.5 1.0 CE A:MET442 4.9 89.0 1.0 O A:MET442 4.9 84.4 1.0 CG A:ASN443 4.9 98.0 1.0 OH A:TYR446 5.0 86.9 1.0 CE2 A:PHE377 5.0 76.2 1.0

Chlorine binding site 2 out of 4 in the Structure of Human TRPC5 in Complex with Clemizole


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Human TRPC5 in Complex with Clemizole within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl801 b:109.5 occ:1.00 CL B:GX0801 0.0 109.5 1.0 C18 B:GX0801 1.8 105.2 1.0 C17 B:GX0801 2.8 100.4 1.0 C16 B:GX0801 2.8 98.2 1.0 CE2 B:TYR446 3.2 79.2 1.0 CB B:MET442 3.4 86.4 1.0 CD2 B:TYR446 3.5 83.3 1.0 CD2 B:PHE414 3.8 95.4 1.0 SD B:MET442 3.8 87.9 1.0 C15 B:GX0801 4.1 97.5 1.0 C14 B:GX0801 4.1 100.6 1.0 OG B:SER489 4.1 74.0 1.0 CG B:MET442 4.1 85.1 1.0 ND2 B:ASN443 4.1 98.9 1.0 CE2 B:PHE414 4.3 95.1 1.0 CG B:PHE414 4.4 94.0 1.0 C B:MET442 4.4 81.3 1.0 CA B:MET442 4.5 81.0 1.0 CZ B:TYR446 4.5 83.6 1.0 N B:ASN443 4.5 86.1 1.0 CB B:PHE414 4.5 90.1 1.0 C9 B:GX0801 4.6 100.6 1.0 CG B:TYR446 4.8 83.5 1.0 CE B:MET442 4.9 89.0 1.0 O B:MET442 4.9 84.4 1.0 CG B:ASN443 4.9 98.0 1.0 OH B:TYR446 5.0 86.9 1.0 CE2 B:PHE377 5.0 76.2 1.0

Chlorine binding site 3 out of 4 in the Structure of Human TRPC5 in Complex with Clemizole


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Human TRPC5 in Complex with Clemizole within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl801 b:109.5 occ:1.00 CL C:GX0801 0.0 109.5 1.0 C18 C:GX0801 1.8 105.2 1.0 C17 C:GX0801 2.8 100.4 1.0 C16 C:GX0801 2.8 98.2 1.0 CE2 C:TYR446 3.2 79.2 1.0 CB C:MET442 3.4 86.4 1.0 CD2 C:TYR446 3.5 83.3 1.0 CD2 C:PHE414 3.8 95.4 1.0 SD C:MET442 3.8 87.9 1.0 C15 C:GX0801 4.1 97.5 1.0 C14 C:GX0801 4.1 100.6 1.0 OG C:SER489 4.1 74.0 1.0 CG C:MET442 4.1 85.1 1.0 ND2 C:ASN443 4.1 98.9 1.0 CE2 C:PHE414 4.3 95.1 1.0 CG C:PHE414 4.4 94.0 1.0 C C:MET442 4.4 81.3 1.0 CA C:MET442 4.5 81.0 1.0 CZ C:TYR446 4.5 83.6 1.0 N C:ASN443 4.5 86.1 1.0 CB C:PHE414 4.5 90.1 1.0 C9 C:GX0801 4.6 100.6 1.0 CG C:TYR446 4.8 83.5 1.0 CE C:MET442 4.9 89.0 1.0 O C:MET442 4.9 84.4 1.0 CG C:ASN443 4.9 98.0 1.0 OH C:TYR446 5.0 86.9 1.0 CE2 C:PHE377 5.0 76.2 1.0

Chlorine binding site 4 out of 4 in the Structure of Human TRPC5 in Complex with Clemizole


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of Human TRPC5 in Complex with Clemizole within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl801 b:109.5 occ:1.00 CL D:GX0801 0.0 109.5 1.0 C18 D:GX0801 1.8 105.2 1.0 C17 D:GX0801 2.8 100.4 1.0 C16 D:GX0801 2.8 98.2 1.0 CE2 D:TYR446 3.2 79.2 1.0 CB D:MET442 3.4 86.4 1.0 CD2 D:TYR446 3.5 83.3 1.0 CD2 D:PHE414 3.8 95.4 1.0 SD D:MET442 3.8 87.9 1.0 C15 D:GX0801 4.1 97.5 1.0 C14 D:GX0801 4.1 100.6 1.0 OG D:SER489 4.1 74.0 1.0 CG D:MET442 4.1 85.1 1.0 ND2 D:ASN443 4.1 98.9 1.0 CE2 D:PHE414 4.3 95.1 1.0 CG D:PHE414 4.4 94.0 1.0 C D:MET442 4.4 81.3 1.0 CA D:MET442 4.5 81.0 1.0 CZ D:TYR446 4.5 83.6 1.0 N D:ASN443 4.5 86.1 1.0 CB D:PHE414 4.5 90.1 1.0 C9 D:GX0801 4.6 100.6 1.0 CG D:TYR446 4.8 83.5 1.0 CE D:MET442 4.9 89.0 1.0 O D:MET442 4.9 84.4 1.0 CG D:ASN443 4.9 98.0 1.0 OH D:TYR446 5.0 86.9 1.0 CE2 D:PHE377 5.0 76.2 1.0

L.Chen, K.Song, M.Wei, W.Guo. Structure of Human TRPC5 in Complex with Clemizole To Be Published.