Chlorine in PDB 7dd5: Structure of Calcium-Sensing Receptor in Complex with Nps-2143

The structure of Structure of Calcium-Sensing Receptor in Complex with Nps-2143 also contains other interesting chemical elements:

Calcium

(Ca)

6 atoms

The binding sites of Chlorine atom in the Structure of Calcium-Sensing Receptor in Complex with Nps-2143 (pdb code 7dd5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Structure of Calcium-Sensing Receptor in Complex with Nps-2143, PDB code: 7dd5:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Structure of Calcium-Sensing Receptor in Complex with Nps-2143


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Calcium-Sensing Receptor in Complex with Nps-2143 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1101 b:143.6 occ:1.00 NH1 A:ARG69 2.8 126.0 1.0 NH2 A:ARG66 3.3 130.3 1.0 NE A:ARG66 3.3 130.3 1.0 CZ A:ARG66 3.8 130.3 1.0 CZ A:ARG69 3.8 126.0 1.0 NH2 A:ARG69 3.9 126.0 1.0 NE1 A:TRP70 3.9 126.7 1.0 N A:ARG414 4.0 134.9 1.0 N A:ILE415 4.1 132.4 1.0 OG A:SER416 4.3 136.3 1.0 CD A:ARG66 4.5 130.3 1.0 CG A:ARG66 4.6 130.3 1.0 O A:HIS412 4.6 148.3 1.0 N A:SER416 4.6 136.3 1.0 CB A:ILE415 4.7 132.4 1.0 CG1 A:ILE415 4.7 132.4 1.0 CA A:LEU413 4.7 142.3 1.0 CB A:ARG414 4.8 134.9 1.0 CA A:ARG414 4.8 134.9 1.0 CD1 A:TRP70 4.8 126.7 1.0 CE2 A:TRP70 4.8 126.7 1.0 CA A:ILE415 4.9 132.4 1.0 C A:LEU413 4.9 142.3 1.0 C A:ARG414 4.9 134.9 1.0 CZ2 A:TRP70 5.0 126.7 1.0

Chlorine binding site 2 out of 4 in the Structure of Calcium-Sensing Receptor in Complex with Nps-2143


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Calcium-Sensing Receptor in Complex with Nps-2143 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1109 b:268.2 occ:1.00 CL1 A:YP11109 0.0 268.2 1.0 C20 A:YP11109 1.8 268.2 1.0 C19 A:YP11109 2.8 268.2 1.0 C21 A:YP11109 2.8 268.2 1.0 C24 A:YP11109 3.0 268.2 1.0 CD1 A:ILE840 3.1 283.7 1.0 N1 A:YP11109 3.7 268.2 1.0 CZ A:PHE683 4.0 295.2 1.0 C18 A:YP11109 4.0 268.2 1.0 C22 A:YP11109 4.0 268.2 1.0 CD1 A:TRP817 4.1 281.7 1.0 CG1 A:VAL816 4.3 292.5 1.0 CE1 A:PHE683 4.3 295.2 1.0 C23 A:YP11109 4.6 268.2 1.0 CG1 A:ILE840 4.6 283.7 1.0 CE1 A:PHE813 4.8 300.8 1.0 CA A:TRP817 4.9 281.7 1.0 NE1 A:TRP817 5.0 281.7 1.0

Chlorine binding site 3 out of 4 in the Structure of Calcium-Sensing Receptor in Complex with Nps-2143


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Calcium-Sensing Receptor in Complex with Nps-2143 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1101 b:142.9 occ:1.00 NH1 B:ARG69 3.2 134.7 1.0 NH2 B:ARG66 3.6 135.2 1.0 NE B:ARG66 3.8 135.2 1.0 N B:ARG414 3.8 141.5 1.0 O B:HIS412 3.9 152.8 1.0 N B:ILE415 4.1 132.3 1.0 CZ B:ARG69 4.2 134.7 1.0 NH2 B:ARG69 4.2 134.7 1.0 CZ B:ARG66 4.2 135.2 1.0 CB B:ARG414 4.4 141.5 1.0 OG B:SER416 4.4 133.4 1.0 CA B:ARG414 4.5 141.5 1.0 NE1 B:TRP70 4.6 131.4 1.0 CA B:LEU413 4.7 146.1 1.0 C B:LEU413 4.7 146.1 1.0 CB B:ILE415 4.8 132.3 1.0 C B:ARG414 4.8 141.5 1.0 N B:SER416 4.9 133.4 1.0 CD B:ARG66 4.9 135.2 1.0 C B:HIS412 4.9 152.8 1.0 CG B:ARG414 5.0 141.5 1.0 CA B:ILE415 5.0 132.3 1.0

Chlorine binding site 4 out of 4 in the Structure of Calcium-Sensing Receptor in Complex with Nps-2143


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of Calcium-Sensing Receptor in Complex with Nps-2143 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1108 b:285.6 occ:1.00 CL1 B:YP11108 0.0 285.6 1.0 C20 B:YP11108 1.8 285.6 1.0 C21 B:YP11108 2.8 285.6 1.0 C19 B:YP11108 2.8 285.6 1.0 C24 B:YP11108 3.0 285.6 1.0 N1 B:YP11108 3.7 285.6 1.0 C18 B:YP11108 4.0 285.6 1.0 C22 B:YP11108 4.0 285.6 1.0 CD1 B:TRP817 4.2 291.0 1.0 CE1 B:PHE683 4.5 299.0 1.0 CG1 B:VAL816 4.6 305.8 1.0 C23 B:YP11108 4.6 285.6 1.0 CZ B:PHE683 4.8 299.0 1.0 CA B:TRP817 4.9 291.0 1.0 CE1 B:PHE813 5.0 311.7 1.0

T.L.Wen, Z.Y.Wang, X.Z.Chen, Y.Ren, X.H.Lu, Y.F.Xing, J.Lu, S.H.Chang, X.Zhang, Y.Q.Shen, X.Yang. Structural Basis For Activation and Allosteric Modulation of Full-Length Calcium-Sensing Receptor. Sci Adv 2021.
ISSN: ESSN 2375-2548
PubMed: 34088669
DOI: 10.1126/SCIADV.ABG1483