Chlorine in PDB 7dxg: Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom

The structure of Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom also contains other interesting chemical elements:

Calcium	(Ca)	8 atoms
Zinc	(Zn)	4 atoms

The binding sites of Chlorine atom in the Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom (pdb code 7dxg). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom, PDB code: 7dxg:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1004 b:135.3 occ:1.00 CL A:HOR1004 0.0 135.3 1.0 C15 A:HOR1004 1.8 106.2 1.0 C17 A:HOR1004 2.8 104.0 1.0 C14 A:HOR1004 2.8 104.6 1.0 O A:HOR1004 3.1 115.8 1.0 CB A:SER752 3.4 92.0 1.0 OG A:SER752 3.7 100.3 1.0 C19 A:HOR1004 4.1 104.4 1.0 C16 A:HOR1004 4.1 97.8 1.0 C1 A:HOR1004 4.4 107.7 1.0 NH1 A:ARG758 4.4 112.7 1.0 C18 A:HOR1004 4.6 101.3 1.0 C4 A:HOR1004 4.7 112.1 1.0 CE1 A:TYR753 4.7 99.2 1.0 OH A:TYR753 4.8 98.0 1.0 CA A:SER752 4.8 96.0 1.0 CZ A:TYR753 4.8 100.1 1.0 C A:HOR1004 4.9 110.0 1.0 CD2 A:TYR612 5.0 104.5 1.0

Chlorine binding site 2 out of 4 in the Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1004 b:135.3 occ:1.00 CL B:HOR1004 0.0 135.3 1.0 C15 B:HOR1004 1.8 106.2 1.0 C17 B:HOR1004 2.8 104.0 1.0 C14 B:HOR1004 2.8 104.6 1.0 O B:HOR1004 3.1 115.8 1.0 CB B:SER752 3.4 92.0 1.0 OG B:SER752 3.7 100.3 1.0 C19 B:HOR1004 4.1 104.4 1.0 C16 B:HOR1004 4.1 97.8 1.0 C1 B:HOR1004 4.4 107.7 1.0 NH1 B:ARG758 4.4 112.7 1.0 C18 B:HOR1004 4.6 101.3 1.0 C4 B:HOR1004 4.7 112.1 1.0 CE1 B:TYR753 4.7 99.2 1.0 OH B:TYR753 4.8 98.0 1.0 CA B:SER752 4.8 96.0 1.0 CZ B:TYR753 4.8 100.1 1.0 C B:HOR1004 4.9 110.0 1.0 CD2 B:TYR612 5.0 104.5 1.0

Chlorine binding site 3 out of 4 in the Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1005 b:135.3 occ:1.00 CL C:HOR1005 0.0 135.3 1.0 C15 C:HOR1005 1.8 106.2 1.0 C17 C:HOR1005 2.8 104.0 1.0 C14 C:HOR1005 2.8 104.6 1.0 O C:HOR1005 3.1 115.8 1.0 CB C:SER752 3.4 92.0 1.0 OG C:SER752 3.7 100.3 1.0 C19 C:HOR1005 4.1 104.4 1.0 C16 C:HOR1005 4.1 97.8 1.0 C1 C:HOR1005 4.4 107.7 1.0 NH1 C:ARG758 4.4 112.7 1.0 C18 C:HOR1005 4.6 101.3 1.0 C4 C:HOR1005 4.7 112.1 1.0 CE1 C:TYR753 4.7 99.2 1.0 OH C:TYR753 4.8 98.0 1.0 CA C:SER752 4.8 96.0 1.0 CZ C:TYR753 4.8 100.1 1.0 C C:HOR1005 4.9 110.0 1.0 CD2 C:TYR612 5.0 104.5 1.0

Chlorine binding site 4 out of 4 in the Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of SAR7334-Bound TRPC6 at 2.9 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1005 b:135.3 occ:1.00 CL D:HOR1005 0.0 135.3 1.0 C15 D:HOR1005 1.8 106.2 1.0 C17 D:HOR1005 2.8 104.0 1.0 C14 D:HOR1005 2.8 104.6 1.0 O D:HOR1005 3.1 115.8 1.0 CB D:SER752 3.4 92.0 1.0 OG D:SER752 3.7 100.3 1.0 C19 D:HOR1005 4.1 104.4 1.0 C16 D:HOR1005 4.1 97.8 1.0 C1 D:HOR1005 4.4 107.7 1.0 NH1 D:ARG758 4.4 112.7 1.0 C18 D:HOR1005 4.6 101.3 1.0 C4 D:HOR1005 4.7 112.1 1.0 CE1 D:TYR753 4.7 99.2 1.0 OH D:TYR753 4.8 98.0 1.0 CA D:SER752 4.8 96.0 1.0 CZ D:TYR753 4.8 100.1 1.0 C D:HOR1005 4.9 110.0 1.0 CD2 D:TYR612 5.0 104.5 1.0

W.Guo, Q.Tang, M.Wei, Y.Kang, J.X.Wu, L.Chen. Structural Mechanism of Human TRPC3 and TRPC6 Channel Regulation By Their Intracellular Calcium-Binding Sites. Neuron V. 110 1023 2022.
ISSN: ISSN 0896-6273
PubMed: 35051376
DOI: 10.1016/J.NEURON.2021.12.023