Chlorine in PDB 7ekp: Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124

The binding sites of Chlorine atom in the Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124 (pdb code 7ekp). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124, PDB code: 7ekp:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:67.2 occ:1.00 CL08 A:I33601 0.0 67.2 1.0 C07 A:I33601 1.8 67.2 1.0 C06 A:I33601 2.7 67.2 1.0 C09 A:I33601 2.8 67.2 1.0 S12 A:I33601 3.6 67.2 1.0 OG B:SER56 3.7 54.9 1.0 OD2 B:ASP186 3.8 65.6 1.0 CB B:ASP186 3.8 65.6 1.0 C10 A:I33601 4.1 67.2 1.0 C05 A:I33601 4.1 67.2 1.0 CG B:ASP186 4.2 65.6 1.0 CB B:SER56 4.5 54.9 1.0 C11 A:I33601 4.6 67.2 1.0 OE1 B:GLN79 4.8 57.9 1.0 O B:LEU57 4.8 55.6 1.0 O B:GLU184 4.9 63.9 1.0

Chlorine binding site 2 out of 5 in the Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl601 b:67.2 occ:1.00 CL08 B:I33601 0.0 67.2 1.0 C07 B:I33601 1.8 67.2 1.0 C06 B:I33601 2.7 67.2 1.0 C09 B:I33601 2.8 67.2 1.0 S12 B:I33601 3.6 67.2 1.0 OG C:SER56 3.6 54.9 1.0 CB C:ASP186 3.8 65.6 1.0 OD2 C:ASP186 3.8 65.6 1.0 C10 B:I33601 4.1 67.2 1.0 C05 B:I33601 4.1 67.2 1.0 CG C:ASP186 4.2 65.6 1.0 CB C:SER56 4.5 54.9 1.0 C11 B:I33601 4.6 67.2 1.0 O C:LEU57 4.8 55.6 1.0 O C:GLU184 4.8 63.9 1.0 OE1 C:GLN79 4.8 57.9 1.0 CA C:ASP186 5.0 65.6 1.0

Chlorine binding site 3 out of 5 in the Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl601 b:67.2 occ:1.00 CL08 C:I33601 0.0 67.2 1.0 C07 C:I33601 1.8 67.2 1.0 C06 C:I33601 2.7 67.2 1.0 C09 C:I33601 2.8 67.2 1.0 S12 C:I33601 3.6 67.2 1.0 OG D:SER56 3.6 54.9 1.0 CB D:ASP186 3.8 65.6 1.0 OD2 D:ASP186 3.8 65.6 1.0 C10 C:I33601 4.1 67.2 1.0 C05 C:I33601 4.1 67.2 1.0 CG D:ASP186 4.2 65.6 1.0 CB D:SER56 4.5 54.9 1.0 C11 C:I33601 4.6 67.2 1.0 O D:LEU57 4.8 55.6 1.0 O D:GLU184 4.8 63.9 1.0 OE1 D:GLN79 4.8 57.9 1.0 CA D:ASP186 5.0 65.6 1.0

Chlorine binding site 4 out of 5 in the Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124 within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl601 b:67.2 occ:1.00 CL08 D:I33601 0.0 67.2 1.0 C07 D:I33601 1.8 67.2 1.0 C06 D:I33601 2.7 67.2 1.0 C09 D:I33601 2.8 67.2 1.0 S12 D:I33601 3.6 67.2 1.0 OG E:SER56 3.6 54.9 1.0 CB E:ASP186 3.8 65.6 1.0 OD2 E:ASP186 3.8 65.6 1.0 C10 D:I33601 4.1 67.2 1.0 C05 D:I33601 4.1 67.2 1.0 CG E:ASP186 4.2 65.6 1.0 CB E:SER56 4.5 54.9 1.0 C11 D:I33601 4.6 67.2 1.0 O E:LEU57 4.7 55.6 1.0 O E:GLU184 4.8 63.9 1.0 OE1 E:GLN79 4.8 57.9 1.0 CA E:ASP186 5.0 65.6 1.0

Chlorine binding site 5 out of 5 in the Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Human Alpha 7 Nicotinic Acetylcholine Receptor Bound to Evp-6124 within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl601 b:67.2 occ:1.00 CL08 E:I33601 0.0 67.2 1.0 C07 E:I33601 1.8 67.2 1.0 C06 E:I33601 2.7 67.2 1.0 C09 E:I33601 2.8 67.2 1.0 S12 E:I33601 3.6 67.2 1.0 OG A:SER56 3.6 54.9 1.0 CB A:ASP186 3.8 65.6 1.0 OD2 A:ASP186 3.8 65.6 1.0 C10 E:I33601 4.1 67.2 1.0 C05 E:I33601 4.1 67.2 1.0 CG A:ASP186 4.2 65.6 1.0 CB A:SER56 4.5 54.9 1.0 C11 E:I33601 4.6 67.2 1.0 O A:LEU57 4.8 55.6 1.0 OE1 A:GLN79 4.8 57.9 1.0 O A:GLU184 4.8 63.9 1.0

Y.Zhao, S.Liu, Y.Zhou, M.Zhang, H.Chen, H.Eric Xu, D.Sun, L.Liu, C.Tian. Structural Basis of Human Alpha 7 Nicotinic Acetylcholine Receptor Activation. Cell Res. 2021.
ISSN: ISSN 1001-0602
PubMed: 33958730
DOI: 10.1038/S41422-021-00509-6