Chlorine »
PDB 7epg-7f6e »
7ex4 »
Chlorine in PDB 7ex4: Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5
Enzymatic activity of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5
All present enzymatic activity of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5:
2.7.7.48;
2.7.7.48;
Protein crystallography data
The structure of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5, PDB code: 7ex4
was solved by
W.Kuang,
Z.Hu,
P.Gong,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 35.41 / 2.00 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 40.933, 70.566, 70.882, 90, 90, 90 |
| R / Rfree (%) | 20.5 / 23.6 |
Other elements in 7ex4:
The structure of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5 also contains other interesting chemical elements:
| Bromine | (Br) | 1 atom |
| Manganese | (Mn) | 2 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5
(pdb code 7ex4). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5, PDB code: 7ex4:
Jump to Chlorine binding site number: 1; 2; 3;
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5, PDB code: 7ex4:
Jump to Chlorine binding site number: 1; 2; 3;
Chlorine binding site 1 out of 3 in 7ex4
Go back to
Chlorine Binding Sites List in 7ex4
Chlorine binding site 1 out
of 3 in the Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5 within 5.0Å range:
|
Chlorine binding site 2 out of 3 in 7ex4
Go back to
Chlorine Binding Sites List in 7ex4
Chlorine binding site 2 out
of 3 in the Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5 within 5.0Å range:
|
Chlorine binding site 3 out of 3 in 7ex4
Go back to
Chlorine Binding Sites List in 7ex4
Chlorine binding site 3 out
of 3 in the Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5 within 5.0Å range:
|
Reference:
W.Kuang,
H.Zhang,
Y.Cai,
G.Zhang,
F.Deng,
H.Li,
Y.Zhou,
M.Wang,
P.Gong,
Y.Guo,
Z.Hu.
Structural and Biochemical Basis For Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ). J.Virol. V. 96 17321 2022.
ISSN: ESSN 1098-5514
PubMed: 35266805
DOI: 10.1128/JVI.02173-21
Page generated: Mon Jul 29 20:37:50 2024
ISSN: ESSN 1098-5514
PubMed: 35266805
DOI: 10.1128/JVI.02173-21
Last articles
Zn in 9JYWZn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
