Atomistry » Chlorine » PDB 7f6k-7fgw » 7f9c
Atomistry »
  Chlorine »
    PDB 7f6k-7fgw »
      7f9c »

Chlorine in PDB 7f9c: Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96

Enzymatic activity of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96

All present enzymatic activity of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96:
6.1.1.15; 6.1.1.17;

Protein crystallography data

The structure of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96, PDB code: 7f9c was solved by N.Malhotra, Y.Manickam, A.Sharma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 62.29 / 2.20
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 70.59, 91.66, 83.38, 90, 110.28, 90
R / Rfree (%) 18.8 / 25.3

Other elements in 7f9c:

The structure of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96 also contains other interesting chemical elements:

Zinc (Zn) 2 atoms
Fluorine (F) 2 atoms
Calcium (Ca) 7 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96 (pdb code 7f9c). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96, PDB code: 7f9c:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 7f9c

Go back to Chlorine Binding Sites List in 7f9c
Chlorine binding site 1 out of 4 in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1904

b:55.9
occ:0.82
 O A:HOH2051 3.2 46.9 1.0
CG A:LYS1484 3.7 58.0 1.0
CB A:PHE1483 3.7 46.4 1.0
CB A:LYS1207 3.9 44.0 1.0
CD A:LYS1207 4.2 55.6 1.0
CB A:LYS1484 4.2 48.2 1.0
CG A:LYS1207 4.2 43.6 1.0
CD2 A:PHE1483 4.3 52.2 1.0
N A:LYS1484 4.3 47.7 1.0
CG A:PHE1483 4.4 54.5 1.0
CD A:LYS1484 4.5 61.9 1.0
CA A:PHE1483 4.6 47.0 1.0
C A:PHE1483 4.7 47.8 1.0
O A:LYS1207 4.7 52.2 1.0
CE A:LYS1207 4.8 63.5 1.0
N A:LYS1207 4.9 44.2 1.0
N A:PHE1483 4.9 46.6 1.0
CA A:LYS1207 4.9 49.9 1.0
CA A:LYS1484 4.9 60.4 1.0

Chlorine binding site 2 out of 4 in 7f9c

Go back to Chlorine Binding Sites List in 7f9c
Chlorine binding site 2 out of 4 in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1905

b:67.9
occ:0.97
 O A:HOH2013 3.3 52.8 1.0
NE1 B:TRP1153 3.6 47.2 1.0
N A:ALA1113 3.7 56.5 1.0
CD2 A:LEU1112 3.7 53.9 1.0
CB A:LEU1112 4.0 45.8 1.0
CE1 B:PHE1155 4.0 51.5 1.0
CZ2 B:TRP1153 4.2 46.8 1.0
NH1 B:ARG1165 4.2 78.6 1.0
CA A:LEU1112 4.3 43.8 1.0
CE2 B:TRP1153 4.3 45.2 1.0
CB A:ALA1113 4.3 63.6 1.0
CG A:LEU1112 4.4 51.7 1.0
C A:LEU1112 4.5 44.3 1.0
CD1 B:PHE1155 4.6 49.3 1.0
CA A:ALA1113 4.6 66.0 1.0
CD1 B:TRP1153 4.8 50.6 1.0
CD1 A:LEU1112 4.8 42.1 1.0

Chlorine binding site 3 out of 4 in 7f9c

Go back to Chlorine Binding Sites List in 7f9c
Chlorine binding site 3 out of 4 in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1905

b:96.7
occ:1.00
 NH2 B:ARG1342 2.8 78.7 1.0
N B:LEU1345 3.4 66.5 1.0
CG B:ARG1346 3.5 55.2 1.0
O B:ALA1343 3.6 65.9 1.0
N B:ARG1346 3.7 63.3 1.0
CZ B:ARG1342 3.9 72.4 1.0
OD1 B:ASP1344 4.0 62.7 1.0
NE B:ARG1342 4.1 55.5 1.0
CA B:ASP1344 4.1 58.9 1.0
C B:LEU1345 4.2 60.9 1.0
C B:ASP1344 4.2 61.0 1.0
CA B:LEU1345 4.2 59.8 1.0
CD B:ARG1346 4.3 61.5 1.0
CA B:ARG1346 4.4 62.3 1.0
CB B:ARG1346 4.4 56.0 1.0
CB B:LEU1345 4.6 57.4 1.0
C B:ALA1343 4.6 62.1 1.0
NE B:ARG1346 4.7 67.6 1.0
CG B:ASP1344 4.8 60.2 1.0
N B:ASP1344 4.9 57.3 1.0

Chlorine binding site 4 out of 4 in 7f9c

Go back to Chlorine Binding Sites List in 7f9c
Chlorine binding site 4 out of 4 in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L96 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1907

b:54.6
occ:0.63
 NE2 B:GLN1159 3.3 68.5 1.0
CD2 B:LEU1024 3.3 51.0 1.0
CG B:LEU1024 3.7 58.4 1.0
N B:ALA1025 3.7 57.3 1.0
CA B:ALA1025 3.7 55.5 1.0
CE B:MET1285 3.8 60.0 1.0
CB B:ALA1025 4.0 45.2 1.0
CB B:LEU1024 4.1 46.2 1.0
C B:LEU1024 4.1 55.6 1.0
OH B:TYR1512 4.2 73.9 1.0
CD B:GLN1159 4.4 71.8 1.0
O B:LEU1024 4.5 59.0 1.0
CA B:LEU1024 4.8 53.5 1.0
OE1 B:GLN1159 4.8 82.4 1.0
CE2 B:TYR1512 4.8 79.2 1.0
NH1 B:ARG1234 5.0 78.2 1.0

Reference:

N.Malhotra, Y.Manickam, A.Sharma. Hsprs with Atp Binding Pocket Inhibitor To Be Published.
Page generated: Mon Jul 29 20:42:30 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy