Chlorine in PDB 7fe0: Avmm Catalyzes Macrocyclization in Alchivemycin A Biosynthesis

The structure of Avmm Catalyzes Macrocyclization in Alchivemycin A Biosynthesis, PDB code: 7fe0 was solved by B.Zhang, H.M.Ge, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.14 / 2.20
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	73.87, 73.87, 243.62, 90, 90, 90
R / Rfree (%)	18.7 / 22

The structure of Avmm Catalyzes Macrocyclization in Alchivemycin A Biosynthesis also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Arsenic	(As)	1 atom

The binding sites of Chlorine atom in the Avmm Catalyzes Macrocyclization in Alchivemycin A Biosynthesis (pdb code 7fe0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Avmm Catalyzes Macrocyclization in Alchivemycin A Biosynthesis, PDB code: 7fe0:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Avmm Catalyzes Macrocyclization in Alchivemycin A Biosynthesis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Avmm Catalyzes Macrocyclization in Alchivemycin A Biosynthesis within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl201 b:77.9 occ:1.00 O A:HOH234 2.9 45.6 1.0 OD2 B:ASP117 2.9 54.8 1.0 O B:SER135 2.9 49.5 1.0 OG B:SER84 3.1 47.0 1.0 CA B:VAL136 3.5 45.7 1.0 C B:SER135 3.9 46.7 1.0 CG B:ASP117 3.9 55.0 1.0 CB B:SER84 3.9 46.7 1.0 CG2 B:VAL136 3.9 48.7 1.0 O B:HOH320 4.0 44.9 1.0 CG2 B:ILE120 4.1 57.8 1.0 CB B:VAL136 4.1 45.0 1.0 N B:VAL136 4.1 47.0 1.0 CD1 B:LEU121 4.2 54.5 1.0 CB B:ASP117 4.2 49.0 1.0 CG B:LEU121 4.2 57.0 1.0 CB B:ILE120 4.2 58.3 1.0 CG1 B:VAL136 4.3 45.0 1.0 N B:THR137 4.4 42.3 1.0 C B:VAL136 4.5 42.1 1.0 CD1 B:ILE120 4.5 48.7 1.0 N B:LEU121 4.8 55.9 1.0 CB B:LEU121 4.9 59.4 1.0 CG1 B:ILE120 5.0 56.5 1.0

Chlorine binding site 2 out of 2 in the Avmm Catalyzes Macrocyclization in Alchivemycin A Biosynthesis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Avmm Catalyzes Macrocyclization in Alchivemycin A Biosynthesis within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl202 b:86.5 occ:1.00 N C:SER169 3.0 56.6 1.0 CA C:LYS168 3.4 66.3 1.0 OG C:SER169 3.5 53.1 1.0 CD C:LYS168 3.5 81.5 1.0 C C:LYS168 3.7 60.0 1.0 CB C:SER169 3.8 51.9 1.0 CB C:LYS168 3.9 68.7 1.0 CA C:SER169 4.0 58.3 1.0 O C:ASP167 4.0 67.0 1.0 CG C:LYS168 4.4 77.5 1.0 N C:LYS168 4.5 66.6 1.0 CE C:LYS168 4.7 86.4 1.0 C C:ASP167 4.7 65.3 1.0 O C:LYS168 4.9 62.2 1.0

H.J.Zhu, B.Zhang, S.H.Liu, L.Xiang, W.Wang, J.P.Zhu, R.H.Jiao, R.X.Tan, H.M.Ge. Avmm Catalyzes Macrocyclization in Alchivemycin A Biosynthesis To Be Published.