Chlorine in PDB 7fwb: Crystal Structure of Human FABP4 in Complex with 5-[2-(2,4- Dichlorophenoxy)Phenyl]-1H-Tetrazole

The structure of Crystal Structure of Human FABP4 in Complex with 5-[2-(2,4- Dichlorophenoxy)Phenyl]-1H-Tetrazole, PDB code: 7fwb was solved by A.Ehler, J.Benz, U.Obst, M.G.Rudolph, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.63 / 1.12
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	32.515, 53.66, 75.289, 90, 90, 90
R / Rfree (%)	15.1 / 18

The binding sites of Chlorine atom in the Crystal Structure of Human FABP4 in Complex with 5-[2-(2,4- Dichlorophenoxy)Phenyl]-1H-Tetrazole (pdb code 7fwb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human FABP4 in Complex with 5-[2-(2,4- Dichlorophenoxy)Phenyl]-1H-Tetrazole, PDB code: 7fwb:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human FABP4 in Complex with 5-[2-(2,4- Dichlorophenoxy)Phenyl]-1H-Tetrazole


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human FABP4 in Complex with 5-[2-(2,4- Dichlorophenoxy)Phenyl]-1H-Tetrazole within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:19.1 occ:1.00 CL17 A:LM9201 0.0 19.1 1.0 C14 A:LM9201 1.7 13.0 1.0 C16 A:LM9201 2.7 13.2 1.0 C10 A:LM9201 2.7 12.5 1.0 O5 A:LM9201 2.9 13.1 1.0 O A:ALA33 3.4 11.4 1.0 O A:HOH346 3.5 13.7 1.0 NH2 A:ARG126 3.7 12.0 1.0 CB A:ALA36 3.9 11.9 1.0 C2 A:LM9201 4.0 13.3 1.0 C15 A:LM9201 4.0 13.8 1.0 C19 A:LM9201 4.0 12.5 1.0 CB A:ALA33 4.1 11.6 1.0 C A:ALA33 4.2 10.2 1.0 C6 A:LM9201 4.2 14.4 1.0 CA A:ALA33 4.3 9.8 1.0 CD2 A:PHE57 4.3 25.4 1.0 CZ A:PHE16 4.5 19.9 1.0 CG A:PRO38 4.5 16.5 1.0 CE2 A:PHE16 4.5 18.2 1.0 C18 A:LM9201 4.5 14.5 1.0 CD A:PRO38 4.7 11.3 1.0 CE2 A:PHE57 4.8 31.0 1.0 CZ A:ARG126 4.9 11.4 1.0 O A:ALA36 5.0 10.9 1.0 CB A:ALA75 5.0 15.4 1.0 CA A:ALA36 5.0 11.0 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human FABP4 in Complex with 5-[2-(2,4- Dichlorophenoxy)Phenyl]-1H-Tetrazole


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human FABP4 in Complex with 5-[2-(2,4- Dichlorophenoxy)Phenyl]-1H-Tetrazole within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:15.0 occ:1.00 CL20 A:LM9201 0.0 15.0 1.0 C19 A:LM9201 1.7 12.5 1.0 C16 A:LM9201 2.7 13.2 1.0 C18 A:LM9201 2.7 14.5 1.0 O A:LYS58 3.0 14.2 1.0 OG A:SER55 3.5 18.5 1.0 CB A:SER53 3.7 12.0 1.0 O A:SER53 3.8 12.7 1.0 C A:SER53 3.8 10.3 1.0 C A:LYS58 3.9 13.2 1.0 C14 A:LM9201 3.9 13.0 1.0 C15 A:LM9201 3.9 13.8 1.0 CB A:SER55 4.0 17.6 1.0 N A:SER55 4.1 12.1 1.0 N A:GLU54 4.1 11.2 1.0 OG1 A:THR60 4.2 13.5 1.0 C A:GLU54 4.2 11.5 1.0 CG2 A:THR60 4.3 14.2 1.0 N A:THR60 4.4 11.0 1.0 CA A:SER53 4.4 10.7 1.0 CB A:PRO38 4.4 12.3 1.0 CA A:ASN59 4.4 11.9 1.0 CA A:GLU54 4.5 11.4 1.0 CB A:ALA75 4.5 15.4 1.0 C10 A:LM9201 4.5 12.5 1.0 CB A:LYS58 4.5 16.7 1.0 N A:ASN59 4.6 12.1 1.0 CA A:SER55 4.6 13.1 1.0 C A:ASN59 4.7 12.6 1.0 CA A:LYS58 4.7 15.4 1.0 O A:GLU54 4.8 12.8 1.0 CB A:THR60 4.8 12.1 1.0 OG A:SER53 4.8 16.0 1.0 N A:LYS58 5.0 19.7 1.0

U.Obst, C.Magnone, B.Kuhn, M.G.Rudolph. Crystal Structure of A Human FABP4 Complex To Be Published.