Chlorine in PDB 7fzy: Crystal Structure of Human FABP4 in Complex with 6-Chloro-4-Phenyl-2- Piperidin-1-Yl-3-(1H-Tetrazol-5-Yl)Quinoline

The structure of Crystal Structure of Human FABP4 in Complex with 6-Chloro-4-Phenyl-2- Piperidin-1-Yl-3-(1H-Tetrazol-5-Yl)Quinoline, PDB code: 7fzy was solved by A.Ehler, J.Benz, U.Obst, H.Kuhne, M.G.Rudolph, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.06 / 1.17
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	32.215, 54.374, 75.143, 90, 90, 90
R / Rfree (%)	13.6 / 17.1

The binding sites of Chlorine atom in the Crystal Structure of Human FABP4 in Complex with 6-Chloro-4-Phenyl-2- Piperidin-1-Yl-3-(1H-Tetrazol-5-Yl)Quinoline (pdb code 7fzy). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human FABP4 in Complex with 6-Chloro-4-Phenyl-2- Piperidin-1-Yl-3-(1H-Tetrazol-5-Yl)Quinoline, PDB code: 7fzy:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human FABP4 in Complex with 6-Chloro-4-Phenyl-2- Piperidin-1-Yl-3-(1H-Tetrazol-5-Yl)Quinoline


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human FABP4 in Complex with 6-Chloro-4-Phenyl-2- Piperidin-1-Yl-3-(1H-Tetrazol-5-Yl)Quinoline within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:15.3 occ:0.70 CL A:65X201 0.0 15.3 0.7 CL A:65X201 0.0 16.0 0.3 C1 A:65X201 1.7 13.6 0.3 C1 A:65X201 1.7 13.3 0.7 C6 A:65X201 2.7 12.0 0.7 C6 A:65X201 2.7 12.8 0.3 C2 A:65X201 2.7 13.9 0.3 C2 A:65X201 2.7 13.8 0.7 CG2 A:THR29 3.6 15.1 1.0 CB A:ASP76 3.6 14.8 1.0 CB A:ALA33 3.7 12.9 1.0 SD A:MET20 3.7 13.1 1.0 CG1 A:VAL25 3.9 13.4 1.0 C5 A:65X201 4.0 11.7 0.7 C3 A:65X201 4.0 12.7 0.7 C3 A:65X201 4.0 13.9 0.3 C5 A:65X201 4.0 12.4 0.3 CE2 A:PHE57 4.1 23.6 1.0 N A:ASP76 4.2 14.0 1.0 CA A:ASP76 4.2 14.5 1.0 CG2 A:VAL25 4.3 13.5 1.0 CG A:ASP76 4.3 14.3 1.0 OD1 A:ASP76 4.5 14.7 1.0 C4 A:65X201 4.5 12.2 0.7 C4 A:65X201 4.5 12.8 0.3 O A:THR29 4.6 11.9 1.0 CG A:MET20 4.6 11.2 1.0 C A:ALA75 4.6 14.0 1.0 CZ A:PHE57 4.6 23.8 1.0 CB A:VAL25 4.7 11.8 1.0 CB A:ALA75 4.7 16.7 1.0 CB A:THR29 4.9 12.1 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human FABP4 in Complex with 6-Chloro-4-Phenyl-2- Piperidin-1-Yl-3-(1H-Tetrazol-5-Yl)Quinoline


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human FABP4 in Complex with 6-Chloro-4-Phenyl-2- Piperidin-1-Yl-3-(1H-Tetrazol-5-Yl)Quinoline within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:16.0 occ:0.30 CL A:65X201 0.0 16.0 0.3 CL A:65X201 0.0 15.3 0.7 C1 A:65X201 1.7 13.6 0.3 C1 A:65X201 1.7 13.3 0.7 C6 A:65X201 2.7 12.0 0.7 C6 A:65X201 2.7 12.8 0.3 C2 A:65X201 2.7 13.9 0.3 C2 A:65X201 2.7 13.8 0.7 CG2 A:THR29 3.6 15.1 1.0 CB A:ASP76 3.6 14.8 1.0 CB A:ALA33 3.7 12.9 1.0 SD A:MET20 3.7 13.1 1.0 CG1 A:VAL25 3.9 13.4 1.0 C5 A:65X201 4.0 11.7 0.7 C3 A:65X201 4.0 12.7 0.7 C5 A:65X201 4.0 12.4 0.3 C3 A:65X201 4.0 13.9 0.3 N A:ASP76 4.1 14.0 1.0 CE2 A:PHE57 4.1 23.6 1.0 CA A:ASP76 4.2 14.5 1.0 CG2 A:VAL25 4.3 13.5 1.0 CG A:ASP76 4.3 14.3 1.0 OD1 A:ASP76 4.5 14.7 1.0 C4 A:65X201 4.5 12.2 0.7 C4 A:65X201 4.5 12.8 0.3 C A:ALA75 4.6 14.0 1.0 O A:THR29 4.6 11.9 1.0 CG A:MET20 4.6 11.2 1.0 CZ A:PHE57 4.6 23.8 1.0 CB A:ALA75 4.7 16.7 1.0 CB A:VAL25 4.7 11.8 1.0 CB A:THR29 5.0 12.1 1.0

U.Obst, C.Magnone, B.Kuhn, M.G.Rudolph. Crystal Structure of A Human FABP4 Complex To Be Published.