Chlorine in PDB 7g0c: Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 2-[2,3-Bis[(2-Chlorophenyl)Methoxy]Phenyl]-2- Methoxyacetic Acid

The structure of Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 2-[2,3-Bis[(2-Chlorophenyl)Methoxy]Phenyl]-2- Methoxyacetic Acid, PDB code: 7g0c was solved by A.Ehler, J.Benz, U.Obst, U.Obst-Sander, M.G.Rudolph, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.11 / 1.14
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	32.107, 52.905, 72.208, 90, 90, 90
R / Rfree (%)	16.5 / 21.3

The binding sites of Chlorine atom in the Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 2-[2,3-Bis[(2-Chlorophenyl)Methoxy]Phenyl]-2- Methoxyacetic Acid (pdb code 7g0c). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 2-[2,3-Bis[(2-Chlorophenyl)Methoxy]Phenyl]-2- Methoxyacetic Acid, PDB code: 7g0c:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 2-[2,3-Bis[(2-Chlorophenyl)Methoxy]Phenyl]-2- Methoxyacetic Acid


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 2-[2,3-Bis[(2-Chlorophenyl)Methoxy]Phenyl]-2- Methoxyacetic Acid within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:25.6 occ:1.00 CL25 A:WA9201 0.0 25.6 1.0 C15 A:WA9201 1.8 25.5 1.0 C12 A:WA9201 2.7 20.1 1.0 C16 A:WA9201 2.8 23.6 1.0 C11 A:WA9201 3.0 23.4 1.0 OG1 A:THR60 3.3 15.0 1.0 CG2 A:THR53 3.5 19.1 1.0 CG2 A:THR60 3.6 17.4 1.0 CB A:THR53 3.7 15.2 1.0 O A:HOH339 3.8 28.6 1.0 CB A:ALA75 3.9 17.7 1.0 CB A:THR60 4.0 13.9 1.0 C19 A:WA9201 4.0 19.8 1.0 C17 A:WA9201 4.0 27.4 1.0 N A:THR60 4.2 11.0 1.0 O9 A:WA9201 4.3 23.3 1.0 CG A:LYS58 4.4 17.1 1.0 O A:THR53 4.5 15.2 1.0 O A:LYS58 4.5 11.5 1.0 OG1 A:THR53 4.5 17.2 1.0 C18 A:WA9201 4.6 22.0 1.0 C A:ASN59 4.6 12.5 1.0 CA A:THR60 4.7 10.4 1.0 C A:THR53 4.8 12.2 1.0 CA A:THR53 4.8 11.7 1.0 O A:HOH400 4.9 26.3 1.0 CA A:ASN59 5.0 11.4 1.0 C A:LYS58 5.0 11.3 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 2-[2,3-Bis[(2-Chlorophenyl)Methoxy]Phenyl]-2- Methoxyacetic Acid


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 2-[2,3-Bis[(2-Chlorophenyl)Methoxy]Phenyl]-2- Methoxyacetic Acid within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:27.6 occ:1.00 CL26 A:WA9201 0.0 27.6 1.0 C24 A:WA9201 1.8 20.0 1.0 C14 A:WA9201 2.7 18.4 1.0 C23 A:WA9201 2.8 23.2 1.0 C13 A:WA9201 3.0 20.7 1.0 OD1 A:ASP76 3.3 15.4 1.0 CG A:ASP76 3.4 15.5 1.0 CD1 A:LEU23 3.6 14.9 1.0 CG2 A:VAL25 3.7 15.6 1.0 CG A:MET20 3.7 12.1 1.0 CB A:ASP76 3.8 15.7 1.0 OD2 A:ASP76 3.9 17.2 1.0 C20 A:WA9201 4.0 20.5 1.0 C22 A:WA9201 4.1 21.7 1.0 NH2 A:ARG78 4.3 13.1 1.0 O10 A:WA9201 4.3 20.3 1.0 SD A:MET20 4.3 14.1 1.0 CB A:MET20 4.4 10.3 1.0 C21 A:WA9201 4.6 20.5 1.0 CA A:MET20 4.6 10.4 1.0 CB A:VAL25 4.8 12.0 1.0 N A:ASP76 4.9 14.7 1.0 CG A:LEU23 4.9 13.4 1.0

U.Obst, C.Magnone, B.Kuhn, M.G.Rudolph. Crystal Structure of A Human FABP4 Binding Site Mutated to That of FABP5 Complex To Be Published.