Chlorine in PDB 7l9j: Crystal Structure of the Second Bromodomain (BD2) of Human BRD2 Bound to RO3280

The structure of Crystal Structure of the Second Bromodomain (BD2) of Human BRD2 Bound to RO3280, PDB code: 7l9j was solved by M.R.Karim, M.J.Bikowitz, E.Schonbrunn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.36 / 1.85
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	52.33, 72.148, 31.938, 90, 90, 90
R / Rfree (%)	16.2 / 20.6

The structure of Crystal Structure of the Second Bromodomain (BD2) of Human BRD2 Bound to RO3280 also contains other interesting chemical elements:

Fluorine

(F)

2 atoms

The binding sites of Chlorine atom in the Crystal Structure of the Second Bromodomain (BD2) of Human BRD2 Bound to RO3280 (pdb code 7l9j). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Second Bromodomain (BD2) of Human BRD2 Bound to RO3280, PDB code: 7l9j:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Second Bromodomain (BD2) of Human BRD2 Bound to RO3280


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Second Bromodomain (BD2) of Human BRD2 Bound to RO3280 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl502 b:17.0 occ:0.50 O A:HOH632 3.0 18.8 1.0 NH1 A:ARG419 3.2 9.9 1.0 CD A:ARG419 3.8 13.0 1.0 CA A:ALA416 4.2 8.7 1.0 CZ A:ARG419 4.3 11.4 1.0 CB A:ALA416 4.4 10.5 1.0 N A:ALA416 4.5 10.6 1.0 NE A:ARG419 4.5 10.6 1.0 O A:HOH698 4.5 35.0 1.0 O A:HOH696 4.6 27.2 1.0 O A:HOH689 4.6 15.1 1.0 C A:ALA415 4.9 13.4 1.0 O A:ALA415 5.0 9.9 1.0

M.R.Karim, M.J.Bikowitz, E.Schonbrunn. Crystal Structure of the Second Bromodomain (BD2) of Human BRD2 Bound to RO3280 To Be Published.